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ONTOLOGY REPORT - ANNOTATIONS


Term:2,3,7,8-tetrabromodibenzodioxine
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Accession:CHEBI:77565 term browser browse the term
Definition:An organobromine compound that is dibenzodioxine carrying four bromo substituents at positions 2, 3, 7 and 8.
Synonyms:exact_synonym: 2,3,7,8-tetrabromooxanthrene
 related_synonym: 2,3,7,8-TBDD;   2,3,7,8-Tetrabromodibenzo-4-dioxin;   2,3,7,8-Tetrabromodibenzo-p-dioxin;   2,3,7,8-Tetrabromodibenzodioxin;   Formula=C12H4Br4O2;   InChI=1S/C12H4Br4O2/c13-5-1-9-10(2-6(5)14)18-12-4-8(16)7(15)3-11(12)17-9/h1-4H;   InChIKey=JZLQUWSWOJPCAK-UHFFFAOYSA-N;   SMILES=Brc1cc2Oc3cc(Br)c(Br)cc3Oc2cc1Br
 xref: Beilstein:273317 "ChemIDplus";   CAS:50585-41-6 "ChemIDplus"
 xref_mesh: MESH:C066841
 xref: PMID:1494962 "Europe PMC";   PMID:19660807 "Europe PMC";   PMID:8484261 "Europe PMC";   Reaxys:273317 "Reaxys"


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2,3,7,8-tetrabromodibenzodioxine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACAD8 acyl-CoA dehydrogenase family member 8 JBrowse link 11 134,253,538 134,265,858 RGD:6480464
G ACADM acyl-CoA dehydrogenase medium chain JBrowse link 1 75,724,347 75,763,679 RGD:6480464
G ACO2 aconitase 2 JBrowse link 22 41,468,756 41,528,979 RGD:6480464
G ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide JBrowse link 4 99,336,497 99,352,746 RGD:6480464
G AHCY adenosylhomocysteinase JBrowse link 20 34,235,012 34,311,976 RGD:6480464
G AHR aryl hydrocarbon receptor JBrowse link 7 17,298,652 17,346,147 RGD:6480464
G ALAD aminolevulinate dehydratase JBrowse link 9 113,386,312 113,401,338 RGD:6480464
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 JBrowse link 3 126,103,561 126,197,758 RGD:6480464
G ALDH2 aldehyde dehydrogenase 2 family member JBrowse link 12 111,766,933 111,817,532 RGD:6480464
G ALDH4A1 aldehyde dehydrogenase 4 family member A1 JBrowse link 1 18,871,430 18,902,799 RGD:6480464
G ALDH7A1 aldehyde dehydrogenase 7 family member A1 JBrowse link 5 126,541,841 126,595,219 RGD:6480464
G ALDH8A1 aldehyde dehydrogenase 8 family member A1 JBrowse link 6 134,917,393 134,950,101 RGD:6480464
G ALDOB aldolase, fructose-bisphosphate B JBrowse link 9 101,420,560 101,435,774 RGD:6480464
G ARG1 arginase 1 JBrowse link 6 131,573,226 131,584,329 RGD:6480464
G ASS1 argininosuccinate synthase 1 JBrowse link 9 130,444,707 130,501,274 RGD:6480464
G BCKDHA branched chain keto acid dehydrogenase E1 subunit alpha JBrowse link 19 41,397,818 41,425,002 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CC2D1B coiled-coil and C2 domain containing 1B JBrowse link 1 52,348,437 52,366,291 RGD:6480464
G CPS1 carbamoyl-phosphate synthase 1 JBrowse link 2 210,477,685 210,679,107 RGD:6480464
G CTH cystathionine gamma-lyase JBrowse link 1 70,411,218 70,441,949 RGD:6480464
G CYB5A cytochrome b5 type A JBrowse link 18 74,250,846 74,291,980 RGD:6480464
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 JBrowse link 15 74,337,762 74,367,646 RGD:6480464
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 JBrowse link 8 142,910,559 142,917,843 RGD:6480464
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 JBrowse link 10 102,830,531 102,837,413 RGD:6480464
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 15 74,719,542 74,725,528 RGD:6480464
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 15 74,748,845 74,756,607 RGD:6480464
G CYP21A2 cytochrome P450 family 21 subfamily A member 2 JBrowse link 6 32,038,306 32,041,670 RGD:6480464
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 JBrowse link 3 186,570,676 186,585,800 RGD:6480464
G DPYS dihydropyrimidinase JBrowse link 8 104,379,429 104,467,074 RGD:6480464
G ENO1 enolase 1 JBrowse link 1 8,861,000 8,878,686 RGD:6480464
G EPHX2 epoxide hydrolase 2 JBrowse link 8 27,491,143 27,597,559 RGD:6480464
G FBP1 fructose-bisphosphatase 1 JBrowse link 9 94,603,133 94,640,263 RGD:6480464
G GLUD1 glutamate dehydrogenase 1 JBrowse link 10 87,050,202 87,094,843 RGD:6480464
G GLUL glutamate-ammonia ligase JBrowse link 1 182,378,093 182,392,206 RGD:6480464
G GOT1 glutamic-oxaloacetic transaminase 1 JBrowse link 10 99,396,870 99,430,624 RGD:6480464
G GPRIN1 G protein regulated inducer of neurite outgrowth 1 JBrowse link 5 176,595,802 176,610,156 RGD:6480464
G GSTZ1 glutathione S-transferase zeta 1 JBrowse link 14 77,321,002 77,331,597 RGD:6480464
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 2 42,767,087 42,801,002 RGD:6480464
G HACL1 2-hydroxyacyl-CoA lyase 1 JBrowse link 3 15,560,699 15,601,569 RGD:6480464
G HPD 4-hydroxyphenylpyruvate dioxygenase JBrowse link 12 121,839,527 121,888,611 RGD:6480464
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 JBrowse link 5 119,452,497 119,542,332 RGD:6480464
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 1 119,414,931 119,423,039 RGD:6480464
G IL5 interleukin 5 JBrowse link 5 132,539,194 132,556,864 RGD:6480464
G INMT indolethylamine N-methyltransferase JBrowse link 7 30,752,135 30,757,602 RGD:6480464
G MCCC2 methylcrotonoyl-CoA carboxylase 2 JBrowse link 5 71,587,340 71,658,706 RGD:6480464
G MDH1 malate dehydrogenase 1 JBrowse link 2 63,588,963 63,607,197 RGD:6480464
G PC pyruvate carboxylase JBrowse link 11 66,848,420 66,958,418 RGD:6480464
G PCCA propionyl-CoA carboxylase subunit alpha JBrowse link 13 100,089,015 100,530,437 RGD:6480464
G PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 JBrowse link X 19,343,893 19,361,718 RGD:6480464
G PM20D1 peptidase M20 domain containing 1 JBrowse link 1 205,828,025 205,850,132 RGD:6480464
G PRDX1 peroxiredoxin 1 JBrowse link 1 45,511,035 45,522,890 RGD:6480464
G PSMA1 proteasome 20S subunit alpha 1 JBrowse link 11 14,504,876 14,643,634 RGD:6480464
G PSMA6 proteasome 20S subunit alpha 6 JBrowse link 14 35,278,558 35,317,493 RGD:6480464
G SHMT1 serine hydroxymethyltransferase 1 JBrowse link 17 18,327,860 18,363,563 RGD:6480464
G SOD1 superoxide dismutase 1 JBrowse link 21 31,659,693 31,668,931 RGD:6480464
G SORD sorbitol dehydrogenase JBrowse link 15 45,023,195 45,077,185 RGD:6480464
G TF transferrin JBrowse link 3 133,661,998 133,796,641 RGD:6480464
G TLK1 tousled like kinase 1 JBrowse link 2 170,990,823 171,231,293 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23754
    role 23643
      biological role 23606
        xenobiotic 19317
          dibenzodioxine 13347
            2,3,7,8-tetrabromodibenzodioxine 58
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  main group element atom 23522
                    p-block element atom 23522
                      carbon group element atom 23232
                        carbon atom 23208
                          organic molecular entity 23208
                            organic molecule 23069
                              organic cyclic compound 22086
                                organic heterocyclic compound 20734
                                  organic heteropolycyclic compound 19860
                                    organic heterotricyclic compound 14178
                                      dibenzodioxine 13347
                                        2,3,7,8-tetrabromodibenzodioxine 58
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.