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ONTOLOGY REPORT - ANNOTATIONS


Term:sulfaphenazole
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Accession:CHEBI:77780 term browser browse the term
Definition:A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
Synonyms:exact_synonym: 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
 related_synonym: 1-phenyl-5-sulfanilamidopyrazole;   3-(p-aminobenzenesulfonamido)-2-phenylpyrazole;   5-sulfanilamido-1-phenylpyrazole;   Formula=C15H14N4O2S;   InChI=1S/C15H14N4O2S/c16-12-6-8-14(9-7-12)22(20,21)18-15-10-11-17-19(15)13-4-2-1-3-5-13/h1-11,18H,16H2;   InChIKey=QWCJHSGMANYXCW-UHFFFAOYSA-N;   N'-(1-phenylpyrazol-5-yl)sulfanilamide;   N(1)-(1-phenylpyrazol-5-yl)sulfanilamide;   SMILES=Nc1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccc1;   Sulfabid;   sulfafenazol;   sulfaphenazol;   sulfaphenazolum;   sulphaphenazole
 xref: CAS:526-08-9 "ChemIDplus";   CAS:526-08-9 "NIST Chemistry WebBook";   DrugBank:DB06729;   Drug_Central:2523 "DrugCentral";   HMDB:HMDB0015667;   KEGG:D01954;   LINCS:LSM-5279
 xref_mesh: MESH:D013426
 xref: PMID:13873771 "Europe PMC";   PMID:18845175 "Europe PMC";   PMID:22785021 "Europe PMC";   PMID:24519941 "Europe PMC";   PMID:9864343 "Europe PMC";   Patent:US2858309;   Reaxys:308518 "Reaxys";   Wikipedia:Sulfaphenazole


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sulfaphenazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 JBrowse link 1 257,676,172 258,004,428 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          sulfonamide antibiotic 195
            sulfaphenazole 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    main group molecular entity 19610
                      s-block molecular entity 19378
                        hydrogen molecular entity 19367
                          hydrides 18278
                            inorganic hydride 17205
                              pnictogen hydride 17167
                                nitrogen hydride 17003
                                  azane 16694
                                    ammonia 16691
                                      organic amino compound 16690
                                        aromatic amine 13592
                                          anilines 12302
                                            substituted aniline 11797
                                              sulfaphenazole 7
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