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ONTOLOGY REPORT - ANNOTATIONS


Term:(1S,2R)-nortilidine
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Accession:CHEBI:77839 term browser browse the term
Definition:A ethyl 2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate that is dextilidine in which one of the methyl groups attached to the nitrogen is replaced by hydrogen. Dextilidine is a prodrug for (1S,2R)-nortilidine, being metabolised to it by the liver.
Synonyms:exact_synonym: ethyl (1S,2R)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate
 related_synonym: (+)-nortilidine;   Formula=C16H21NO2;   InChI=1S/C16H21NO2/c1-3-19-15(18)16(13-9-5-4-6-10-13)12-8-7-11-14(16)17-2/h4-7,9-11,14,17H,3,8,12H2,1-2H3/t14-,16+/m1/s1;   InChIKey=PDJZPNKVLDWEKI-ZBFHGGJFSA-N;   SMILES=CCOC(=O)[C@@]1(CCC=C[C@H]1NC)c1ccccc1;   ethyl trans-(+)-2-(methylamino)-1-phenyl-3-cyclohexene-1-carboxylate
 xref: CAS:37815-44-4 "ChemIDplus";   Reaxys:8864203 "Reaxys"
 cyclic_relationship: is_enantiomer_of CHEBI:77841


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Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      biological role 19693
        pharmacological role 18802
          analgesic 13061
            opioid analgesic 632
              (1S,2R)-nortilidine 0
                rac-nortilidine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic group 18426
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18306
                                    carbonyl compound 18306
                                      carboxylic acid 17973
                                        amino acid 12448
                                          non-proteinogenic amino acid 1732
                                            beta-amino acid 172
                                              beta-amino acid ester 128
                                                ethyl 2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate 0
                                                  (1S,2R)-nortilidine 0
                                                    rac-nortilidine 0
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