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Accession:CHEBI:77841 term browser browse the term
Definition:An ethyl 2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate that is ent-dextilidine in which one of the methyl groups attached to the nitrogen is replaced by hydrogen. ent-Dextilidine is metabolised to (1R,2S)-nortilidine by the liver.
Synonyms:exact_synonym: ethyl (1R,2S)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate
 related_synonym: (-)-nortilidine;   Formula=C16H21NO2;   InChI=1S/C16H21NO2/c1-3-19-15(18)16(13-9-5-4-6-10-13)12-8-7-11-14(16)17-2/h4-7,9-11,14,17H,3,8,12H2,1-2H3/t14-,16+/m0/s1;   InChIKey=PDJZPNKVLDWEKI-GOEBONIOSA-N;   SMILES=CCOC(=O)[C@]1(CCC=C[C@@H]1NC)c1ccccc1;   ethyl trans-(-)-2-(methylamino)-1-phenyl-3-cyclohexene-1-carboxylate
 cyclic_relationship: is_enantiomer_of CHEBI:77839

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Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        pharmacological role 18794
          antagonist 16201
            excitatory amino acid antagonist 10083
              NMDA receptor antagonist 8597
                (1R,2S)-nortilidine 0
                  rac-nortilidine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic group 18414
                              organic divalent group 18406
                                organodiyl group 18406
                                  carbonyl group 18295
                                    carbonyl compound 18295
                                      carboxylic acid 17963
                                        amino acid 12446
                                          non-proteinogenic amino acid 1733
                                            beta-amino acid 172
                                              beta-amino acid ester 128
                                                ethyl 2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate 0
                                                  (1R,2S)-nortilidine 0
                                                    rac-nortilidine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.