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ONTOLOGY REPORT - ANNOTATIONS


Term:oseltamivir
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Accession:CHEBI:7798 term browser browse the term
Definition:A cyclohexenecarboxylate ester that is the ethyl ester of oseltamivir acid. An antiviral prodrug (it is hydrolysed to the active free carboxylic acid in the liver), it is used to slow the spread of influenza.
Synonyms:exact_synonym: ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
 related_synonym: 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha,4beta,5alpha))-;   Agucort;   Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate;   Formula=C16H28N2O4;   GS-4104;   HSDB 7433;   InChI=1S/C16H28N2O4/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19/h9,12-15H,5-8,17H2,1-4H3,(H,18,19)/t13-,14+,15+/m0/s1;   InChIKey=VSZGPKBBMSAYNT-RRFJBIMHSA-N;   SMILES=CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1;   Tamiflu;   oseltamivirum
 alt_id: CHEBI:42582
 xref: Beilstein:8003908 "Beilstein";   CAS:196618-13-0 "ChemIDplus";   CAS:196618-13-0 "KEGG COMPOUND";   DrugBank:DB00198;   Drug_Central:2001 "DrugCentral";   HMDB:HMDB0014343;   KEGG:C08092;   KEGG:D08306
 xref_mesh: MESH:D053139
 xref: PMID:11075941 "Europe PMC";   PMID:11270942 "Europe PMC";   PMID:11825310 "Europe PMC";   PMID:17912363 "Europe PMC";   PMID:18559644 "Europe PMC";   PMID:18936828 "Europe PMC";   PMID:19355841 "Europe PMC";   PMID:19439487 "Europe PMC";   PMID:19557131 "Europe PMC";   PMID:19884755 "Europe PMC";   Patent:US5763483;   Reaxys:8003908 "Reaxys";   Wikipedia:Oseltamivir


show annotations for term's descendants       view all columns           Sort by:
 
oseltamivir term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        xenobiotic 18322
          oseltamivir 4
            oseltamivir phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        carboacyl group 17073
                                          univalent carboacyl group 17073
                                            carbamoyl group 16800
                                              carboxamide 16800
                                                acetamides 11598
                                                  oseltamivir 4
                                                    oseltamivir phosphate 0
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