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ONTOLOGY REPORT - ANNOTATIONS


Term:oseltamivir
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Accession:CHEBI:7798 term browser browse the term
Definition:A cyclohexenecarboxylate ester that is the ethyl ester of oseltamivir acid. An antiviral prodrug (it is hydrolysed to the active free carboxylic acid in the liver), it is used to slow the spread of influenza.
Synonyms:exact_synonym: ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
 related_synonym: 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha,4beta,5alpha))-;   Agucort;   Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate;   Formula=C16H28N2O4;   GS-4104;   HSDB 7433;   InChI=1S/C16H28N2O4/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19/h9,12-15H,5-8,17H2,1-4H3,(H,18,19)/t13-,14+,15+/m0/s1;   InChIKey=VSZGPKBBMSAYNT-RRFJBIMHSA-N;   SMILES=CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1;   Tamiflu;   oseltamivirum
 alt_id: CHEBI:42582
 xref: Beilstein:8003908 "Beilstein";   CAS:196618-13-0 "ChemIDplus";   CAS:196618-13-0 "KEGG COMPOUND";   DrugBank:DB00198;   Drug_Central:2001 "DrugCentral";   HMDB:HMDB0014343;   KEGG:C08092;   KEGG:D08306
 xref_mesh: MESH:D053139
 xref: PMID:11075941 "Europe PMC";   PMID:11270942 "Europe PMC";   PMID:11825310 "Europe PMC";   PMID:17912363 "Europe PMC";   PMID:18559644 "Europe PMC";   PMID:18936828 "Europe PMC";   PMID:19355841 "Europe PMC";   PMID:19439487 "Europe PMC";   PMID:19557131 "Europe PMC";   PMID:19884755 "Europe PMC";   Patent:US5763483;   Reaxys:8003908 "Reaxys";   Wikipedia:Oseltamivir


show annotations for term's descendants       view all columns           Sort by:
 
oseltamivir term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      biological role 19693
        xenobiotic 18344
          oseltamivir 4
            oseltamivir phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic group 18426
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18306
                                    carbonyl compound 18306
                                      carboxylic acid 17973
                                        carboacyl group 17082
                                          univalent carboacyl group 17082
                                            carbamoyl group 16811
                                              carboxamide 16811
                                                acetamides 11612
                                                  oseltamivir 4
                                                    oseltamivir phosphate 0
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