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ONTOLOGY REPORT - ANNOTATIONS


Term:huperzine A
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Accession:CHEBI:78330 term browser browse the term
Definition:A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity.
Synonyms:exact_synonym: (5R,9R,11E)-5-amino-11-ethylidene-7-methyl-5,6,9,10-tetrahydro-5,9-methanocycloocta[b]pyridin-2(1H)-one
 related_synonym: (-)-huperazine A;   Formula=C15H18N2O;   InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15+/m0/s1;   InChIKey=ZRJBHWIHUMBLCN-YQEJDHNASA-N;   SMILES=C\\C=C1/[C@@H]2Cc3[nH]c(=O)ccc3[C@@]1(N)CC(C)=C2;   selagine
 xref: CAS:102518-79-6;   DrugBank:DB04864
 xref_mesh: MESH:C050426
 xref: PMID:12895686;   PMID:23306162;   PMID:24129696;   PMID:24190328;   PMID:24299147;   PMID:24332448;   PMID:24639880;   Reaxys:3592896;   Wikipedia:Huperzine_A


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huperzine A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:6480464
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 JBrowse link 12 11,053,888 11,082,742 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      application 19363
        refrigerant 17249
          ammonia 16703
            organic amino compound 16702
              primary amino compound 7836
                huperzine A 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    main group molecular entity 19655
                      s-block molecular entity 19398
                        hydrogen molecular entity 19388
                          hydrides 18363
                            organic hydride 17714
                              organic fundamental parent 17714
                                hydrocarbon 17201
                                  terpene 9490
                                    terpenoid 9485
                                      sesquiterpenoid 2691
                                        sesquiterpene alkaloid 9
                                          huperzine A 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.