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ONTOLOGY REPORT - ANNOTATIONS


Term:guanosine 5'-[beta,gamma-imido]triphosphate
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Accession:CHEBI:78408 term browser browse the term
Definition:A nucleoside triphosphate analogue that is GTP in which the oxygen atom bridging the beta- to the gamma- phosphate is replaced by a nitrogen atom A non-hydrolyzable analog of GTP, it binds tightly to G-protein in the presence of Mg(2+).
Synonyms:exact_synonym: 5'-O-(hydroxy{[hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl)guanosine
 related_synonym: 5'-Guanylic acid, monoanhydride with imidodiphosphoric acid;   5'-guanylylimidodiphosphate;   Formula=C10H17N6O13P3;   GMP-Pnp;   Gpp(NH)p;   Guanylyl imidodiphosphate;   InChI=1S/C10H17N6O13P3/c11-10-13-7-4(8(19)14-10)12-2-16(7)9-6(18)5(17)3(28-9)1-27-32(25,26)29-31(23,24)15-30(20,21)22/h2-3,5-6,9,17-18H,1H2,(H,25,26)(H3,11,13,14,19)(H4,15,20,21,22,23,24)/t3-,5-,6-,9-/m1/s1;   InChIKey=UQABYHGXWYXDTK-UUOKFMHZSA-N;   SMILES=Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)NP(O)(O)=O)[C@@H](O)[C@H]1O
 alt_id: CHEBI:42862
 xref: CAS:34273-04-6 "ChemIDplus"
 xref_mesh: MESH:D006165
 xref: PDBeChem:GNP;   PMID:1547891 "Europe PMC";   PMID:166994 "Europe PMC";   PMID:1672318 "Europe PMC";   PMID:188052 "Europe PMC";   PMID:3103629 "Europe PMC";   PMID:3159604 "Europe PMC";   PMID:4607368 "Europe PMC";   Reaxys:1201190 "Reaxys";   Wikipedia:5'-Guanylyl_imidodiphosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:78409


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guanosine 5'-[beta,gamma-imido]triphosphate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrm3 cholinergic receptor, muscarinic 3 JBrowse link 17 63,990,599 64,463,222 RGD:6480464
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:6480464
G Gmds GDP-mannose 4, 6-dehydratase JBrowse link 17 33,408,722 33,938,086 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:6480464
G Ptgdr prostaglandin D2 receptor JBrowse link 15 19,195,606 19,196,508 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        solvent 16079
          phosphoric acid 7332
            phosphoric acid derivative 6983
              organic phosphate 6982
                nucleoside phosphate 1503
                  nucleoside triphosphate analogue 38
                    guanosine 5'-[beta,gamma-imido]triphosphate 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      chalcogen 19334
                        oxygen atom 19295
                          oxygen molecular entity 19295
                            hydroxides 19048
                              oxoacid 18111
                                pnictogen oxoacid 9840
                                  phosphorus oxoacid 8659
                                    phosphoric acids 7332
                                      phosphoric acid 7332
                                        phosphoric acid derivative 6983
                                          phosphate 6983
                                            organic phosphate 6982
                                              nucleoside phosphate 1503
                                                nucleoside triphosphate analogue 38
                                                  guanosine 5'-[beta,gamma-imido]triphosphate 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.