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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:78433 term browser browse the term
Definition:A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a 'R' number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
Synonyms:related_synonym: refrigerants
 xref: Wikipedia:Refrigerant

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  CHEBI ontology 19785
    role 19732
      application 19391
        refrigerant 17418
          ammonia + 16939
          butane + 71
          carbon dioxide 20
          chloroform + 116
          chloromethane 2
          dichloromethane 184
          diethyl ether 0
          difluoromethane + 0
          dinitrogen oxide 8
          ethane + 6284
          ethene + 3862
          fluoroform + 6329
          fluoromethane 0
          hexachloroethane 0
          hexafluoroethane 0
          isobutane + 695
          isopentane + 2
          methyl formate 0
          pentane + 212
          propene + 2
          sulfur dioxide 122
          tetrachloromethane 7182
          tetrafluoromethane + 6329
          trichlorofluoromethane 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.