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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:9-[2-(phosphonomethoxy)ethyl]guanine
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Accession:CHEBI:7880 term browser browse the term
Definition:A phosphoethanolamine that has formula C8H12N5O5P.
Synonyms:related_synonym: 9-((2-Phosphonylmethoxy)ethyl)guanine;   Formula=C8H12N5O5P;   InChI=1S/C8H12N5O5P/c9-8-11-6-5(7(14)12-8)10-3-13(6)1-2-18-4-19(15,16)17/h3H,1-2,4H2,(H2,15,16,17)(H3,9,11,12,14);   InChIKey=NZVORGQIEFTOQZ-UHFFFAOYSA-N;   PMEG;   SMILES=Nc1nc(=O)c2ncn(CCOCP(O)(O)=O)c2[nH]1
 xref: CAS:114088-58-3;   KEGG:C11184
 xref_mesh: MESH:C063380


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9-[2-(phosphonomethoxy)ethyl]guanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a6 solute carrier family 22 member 6 multiple interactions
increases response to substance
ISO 9-((2-phosphonylmethoxy)ethyl)guanine analog inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine]; Quercetin inhibits the reaction [SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine analog]
SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine; SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine analog
CTD PMID:23856525 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
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Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        biochemical role 19304
          metabolite 19285
            eukaryotic metabolite 18934
              algal metabolite 13596
                guanine 3973
                  9-[2-(phosphonomethoxy)ethyl]guanine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  organic heteropolycyclic compound 17838
                                    organic heterobicyclic compound 16763
                                      imidazopyrimidine 5444
                                        purines 5442
                                          aminopurine 4399
                                            2-aminopurines 4009
                                              guanine 3973
                                                9-[2-(phosphonomethoxy)ethyl]guanine 1
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