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ONTOLOGY REPORT - ANNOTATIONS


Term:tirapazamine
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Accession:CHEBI:78887 term browser browse the term
Definition:A member of the class of benzotriazines that is 1,2,4-benzotriazine carrying an amino substituent at position 3 and two oxido substituents at positions 1 and 4.
Synonyms:exact_synonym: 1,2,4-benzotriazin-3-amine 1,4-dioxide
 related_synonym: 3-Amino-1,2,4-benzotriazine 1,4-dioxide;   Formula=C7H6N4O2;   InChI=1S/C7H6N4O2/c8-7-9-11(13)6-4-2-1-3-5(6)10(7)12/h1-4H,(H2,8,9);   InChIKey=ORYDPOVDJJZGHQ-UHFFFAOYSA-N;   SMILES=Nc1n[n+]([O-])c2ccccc2[n+]1[O-];   SR 4233
 xref: Beilstein:179322 "ChemIDplus";   CAS:27314-97-2 "ChemIDplus";   CAS:27314-97-2 "KEGG DRUG";   KEGG:D06167
 xref_mesh: MESH:C049947
 xref: PMID:22331808 "Europe PMC";   PMID:22531857 "Europe PMC";   PMID:22666522 "Europe PMC";   PMID:22946564 "Europe PMC";   PMID:23033890 "Europe PMC";   PMID:23888874 "Europe PMC";   PMID:24362462 "Europe PMC";   PMID:24395863 "Europe PMC";   PMID:24529061 "Europe PMC";   PMID:7954337 "Europe PMC";   Reaxys:179322 "Reaxys";   Wikipedia:Tirapazamine


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tirapazamine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          antibacterial agent 12926
            tirapazamine 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic molecule 19417
                              organic cyclic compound 19184
                                organic heterocyclic compound 18262
                                  organic heteropolycyclic compound 17570
                                    organic heterobicyclic compound 16240
                                      mancude organic heterobicyclic parent 5176
                                        benzotriazine 13
                                          1,2,4-benzotriazine 7
                                            tirapazamine 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.