Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Nonylphenol
go back to main search page
Accession:CHEBI:79516 term browser browse the term
Synonyms:xref: CAS:25154-52-3;   KEGG:C14993
 xref_mesh: MESH:C025256


show annotations for term's descendants           Sort by:
 
Nonylphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP nonylphenol results in increased expression of ABCB1A mRNA CTD PMID:20961954 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP nonylphenol results in increased expression of ABCB1B mRNA CTD PMID:20961954 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Actb actin, beta increases expression EXP nonylphenol results in increased expression of ACTB protein CTD PMID:19260726 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actr1a actin related protein 1A increases expression EXP nonylphenol results in increased expression of ACTR1A protein CTD PMID:19260726 NCBI chr 1:266,123,864...266,142,621
Ensembl chr 1:266,123,870...266,142,538
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing affects expression
increases expression
ISO
EXP
nonylphenol affects the expression of ADIPOQ mRNA
nonylphenol results in increased expression of ADIPOQ mRNA
CTD PMID:17010207, PMID:18417718 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adra2c adrenoceptor alpha 2C decreases expression EXP nonylphenol results in decreased expression of ADRA2C mRNA CTD PMID:15620428 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Ahcy adenosylhomocysteinase decreases expression EXP nonylphenol results in decreased expression of AHCY protein CTD PMID:19260726 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO nonylphenol inhibits the reaction [AHR protein binds to CYP1A1 promoter] CTD PMID:11248424 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression EXP nonylphenol results in increased expression of AIF1 protein CTD PMID:30481583 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases expression EXP nonylphenol results in increased expression of AKR1B8 protein CTD PMID:19260726 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP nonylphenol results in decreased expression of AKT1 mRNA CTD PMID:27832966 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP nonylphenol results in increased expression of ALAS1 mRNA CTD PMID:17010207 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases expression EXP nonylphenol results in increased expression of ALDH5A1 mRNA CTD PMID:17010207 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [nonylphenol binds to ESR1 protein] which results in increased activity of ALPL protein CTD PMID:12650720 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Anxa3 annexin A3 increases expression EXP nonylphenol results in increased expression of ANXA3 protein CTD PMID:19260726 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Anxa7 annexin A7 decreases expression EXP nonylphenol results in decreased expression of ANXA7 protein CTD PMID:19260726 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Apeh acylaminoacyl-peptide hydrolase increases expression EXP nonylphenol results in increased expression of APEH mRNA CTD PMID:17010207 NCBI chr 8:116,862,664...116,871,776
Ensembl chr 8:116,862,625...116,872,215
JBrowse link
G Apob apolipoprotein B increases expression EXP nonylphenol results in increased expression of APOB mRNA CTD PMID:17010207 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Ar androgen receptor increases expression
multiple interactions
decreases activity
decreases expression
affects binding
ISO
EXP
nonylphenol results in increased expression of AR mRNA
nonylphenol inhibits the reaction [Metribolone results in increased activity of AR protein]
nonylphenol results in decreased activity of AR protein
nonylphenol analog results in decreased expression of AR mRNA
nonylphenol binds to AR protein
nonylphenol inhibits the reaction [Dihydrotestosterone binds to AR protein]
CTD PMID:12805653, PMID:14565775, PMID:15159206, PMID:20371976, PMID:25242005, PMID:26867867, PMID:29427707 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO nonylphenol results in decreased expression of ARHGDIA mRNA CTD PMID:15159206 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 decreases expression EXP nonylphenol results in decreased expression of ARPC2 protein CTD PMID:19260726 NCBI chr 9:81,518,163...81,548,871
Ensembl chr 9:81,518,176...81,548,871
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression EXP nonylphenol results in increased expression of ATP5F1B protein CTD PMID:19260726 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP increases expression EXP nonylphenol results in increased expression of ATP5PO mRNA CTD PMID:17010207 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 increases expression EXP nonylphenol results in increased expression of ATP6AP1 mRNA CTD PMID:17010207 NCBI chr  X:156,407,973...156,415,053
Ensembl chr  X:156,407,937...156,415,145
JBrowse link
G Avpr1b arginine vasopressin receptor 1B decreases expression EXP nonylphenol results in decreased expression of AVPR1B mRNA CTD PMID:15620428 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Avpr2 arginine vasopressin receptor 2 decreases expression EXP nonylphenol results in decreased expression of AVPR2 mRNA CTD PMID:15620428 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO nonylphenol results in increased expression of BAX protein CTD PMID:23677851 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
ISO nonylphenol results in increased expression of BCL2 protein
nonylphenol results in decreased expression of BCL2 protein
CTD PMID:23677851, PMID:24604882 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Blvrb biliverdin reductase B increases expression EXP nonylphenol results in increased expression of BLVRB protein CTD PMID:19260726 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G C3 complement C3 increases expression ISO
EXP
nonylphenol results in increased expression of C3 protein
nonylphenol results in increased expression of C3 mRNA; nonylphenol results in increased expression of C3 protein
CTD PMID:11086226, PMID:11390168 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta decreases expression EXP nonylphenol results in decreased expression of CAPZB protein CTD PMID:19260726 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases cleavage
decreases expression
EXP
ISO
nonylphenol results in increased expression of CASP3 protein modified form
Acetylcysteine affects the reaction [nonylphenol results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [nonylphenol results in increased cleavage of CASP3 protein]
nonylphenol results in decreased expression of CASP3 protein
CTD PMID:17065434, PMID:23677851, PMID:27832966 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casr calcium-sensing receptor decreases expression EXP nonylphenol results in decreased expression of CASR mRNA CTD PMID:15620428 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cat catalase decreases activity EXP nonylphenol results in decreased activity of CAT protein CTD PMID:21472897 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO fulvestrant inhibits the reaction [nonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; nonylphenol inhibits the reaction [IL1A protein promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to CCL2 promoter]]; nonylphenol inhibits the reaction [IL1A protein results in increased expression of CCL2 mRNA]; nonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein] CTD PMID:10614622 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccn5 cellular communication network factor 5 increases expression ISO nonylphenol results in increased expression of CCN5 mRNA CTD PMID:10944450 NCBI chr 3:160,207,969...160,219,316
Ensembl chr 3:160,207,913...160,219,331
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
ISO [nonylphenol co-treated with Resveratrol] results in decreased expression of CCND1 mRNA; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of CCND1 mRNA]
nonylphenol results in increased expression of CCND1 mRNA; nonylphenol results in increased expression of CCND1 protein
CTD PMID:22552626, PMID:27260121, PMID:27366082 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 increases expression ISO nonylphenol results in increased expression of CCNE1 mRNA CTD PMID:27260121 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdh1 cadherin 1 decreases expression
multiple interactions
ISO nonylphenol results in decreased expression of CDH1 protein
fulvestrant inhibits the reaction [nonylphenol results in decreased expression of CDH1 protein]; Genistein inhibits the reaction [nonylphenol results in decreased expression of CDH1 protein]
CTD PMID:25690688, PMID:26407941 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 decreases expression
affects expression
increases expression
ISO
EXP
nonylphenol analog results in decreased expression of CDH2 mRNA
nonylphenol affects the expression of CDH2 mRNA
nonylphenol results in decreased expression of CDH2 protein
nonylphenol analog results in increased expression of CDH2 mRNA
CTD PMID:25242005, PMID:27832966 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
increases expression
ISO [nonylphenol co-treated with resveratrol] results in decreased expression of CDK2 mRNA
nonylphenol results in increased expression of CDK2 mRNA
CTD PMID:22552626 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions EXP nonylphenol affects the reaction [CGA protein results in increased expression of CYP11A1 protein]; nonylphenol affects the reaction [CGA protein results in increased expression of STAR protein]; nonylphenol inhibits the reaction [CGA protein results in increased secretion of Testosterone] CTD PMID:19883722 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 decreases expression EXP nonylphenol results in decreased expression of CHRM2 mRNA CTD PMID:15620428 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Cldn1 claudin 1 decreases expression EXP nonylphenol results in decreased expression of CLDN1 protein CTD PMID:32240654 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Clu clusterin decreases expression EXP nonylphenol results in decreased expression of CLU mRNA CTD PMID:17558187 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP nonylphenol results in decreased expression of CNR1 mRNA CTD PMID:15620428 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression EXP nonylphenol results in decreased expression of CPT1A protein CTD PMID:29641977 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO nonylphenol results in increased phosphorylation of and results in increased localization of and results in increased activity of CREB1 protein CTD PMID:20954072 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
ISO [nonylphenol results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA; ESR1 protein promotes the reaction [nonylphenol promotes the reaction [ESR1 protein binds to CTSD promoter]]; fulvestrant inhibits the reaction [nonylphenol promotes the reaction [ESR1 protein binds to CTSD promoter]]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of CTSD protein]; Genistein inhibits the reaction [nonylphenol results in increased expression of CTSD protein]; nonylphenol promotes the reaction [ESR1 protein binds to CTSD promoter]; nonylphenol promotes the reaction [NCOA1 protein binds to CTSD promoter] CTD PMID:14754635, PMID:26407941, PMID:27366082 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP nonylphenol results in increased expression of CXCL10 mRNA CTD PMID:17010207 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP nonylphenol affects the reaction [CGA protein results in increased expression of CYP11A1 protein]
nonylphenol analog results in decreased expression of CYP11A1 mRNA
CTD PMID:19883722, PMID:22771390 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases activity
decreases activity
ISO [Dichlorodiphenyl Dichloroethylene co-treated with nonylphenol] results in increased activity of CYP19A1 protein; bis(tri-n-butyltin)oxide promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]; bisphenol A promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]; Chlordecone promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]; nonylphenol promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]; nonylphenol promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]; nonylphenol promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]
nonylphenol results in increased activity of CYP19A1 protein
CTD PMID:17599374, PMID:27825933 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO nonylphenol inhibits the reaction [AHR protein binds to CYP1A1 promoter]; nonylphenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; nonylphenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:11248424 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO nonylphenol results in increased expression of CYP26A1 mRNA CTD PMID:31288075 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO nonylphenol results in increased expression of CYP2B10 mRNA
NR1I3 gene mutant form affects the reaction [nonylphenol results in increased expression of CYP2B10 mRNA]
CTD PMID:19041682 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 results in increased metabolism of nonylphenol CTD PMID:9817083 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity
decreases expression
EXP nonylphenol results in decreased activity of CYP2C11 protein
nonylphenol results in decreased expression of CYP2C11 protein
CTD PMID:11731036 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression
multiple interactions
ISO nonylphenol results in increased expression of CYP2C29 mRNA
NR1I3 gene mutant form affects the reaction [nonylphenol results in increased expression of CYP2C29 mRNA]
CTD PMID:19041682 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP nonylphenol results in increased expression of CYP3A23-3A1 mRNA CTD PMID:10707959 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Dazl deleted in azoospermia-like increases expression ISO nonylphenol results in increased expression of DAZL mRNA CTD PMID:31288075 NCBI chr 9:12,633,983...12,651,017
Ensembl chr 9:12,633,990...12,650,938
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP nonylphenol results in increased expression of DDIT3 mRNA; nonylphenol results in increased expression of DDIT3 protein CTD PMID:19429228 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddx4 DEAD-box helicase 4 increases expression ISO nonylphenol results in increased expression of DDX4 mRNA CTD PMID:31288075 NCBI chr 2:44,447,610...44,504,263
Ensembl chr 2:44,447,573...44,504,354
JBrowse link
G Des desmin increases expression EXP nonylphenol results in increased expression of DES protein CTD PMID:19260726 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression EXP nonylphenol results in decreased expression of DLD protein CTD PMID:19260726 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dmc1 DNA meiotic recombinase 1 increases expression ISO nonylphenol results in increased expression of DMC1 mRNA CTD PMID:31288075 NCBI chr 7:120,796,217...120,840,524
Ensembl chr 7:120,796,217...120,839,577
JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 increases expression ISO nonylphenol results in increased expression of DMRT1 mRNA CTD PMID:31288075 NCBI chr 1:243,477,403...243,582,629
Ensembl chr 1:243,477,493...243,582,629
JBrowse link
G Dppa3 developmental pluripotency-associated 3 increases expression ISO nonylphenol results in increased expression of DPPA3 mRNA CTD PMID:31288075 NCBI chr 4:155,437,675...155,441,059
Ensembl chr 3:111,298,713...111,299,189
Ensembl chr 4:111,298,713...111,299,189
JBrowse link
G Drd1 dopamine receptor D1 decreases expression EXP nonylphenol results in decreased expression of DRD1 mRNA CTD PMID:15620428 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 increases expression EXP nonylphenol results in increased expression of DRD2 mRNA CTD PMID:15620428 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dsp desmoplakin increases expression EXP nonylphenol results in increased expression of DSP protein CTD PMID:19260726 NCBI chr17:27,286,811...27,334,453
Ensembl chr17:27,286,796...27,334,379
JBrowse link
G Ednrb endothelin receptor type B increases expression EXP nonylphenol results in increased expression of EDNRB mRNA CTD PMID:15620428 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egr3 early growth response 3 increases expression ISO nonylphenol results in increased expression of EGR3 mRNA CTD PMID:15159206 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Eno1 enolase 1 decreases expression EXP nonylphenol results in decreased expression of ENO1 protein CTD PMID:19260726 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Eno2 enolase 2 decreases expression ISO nonylphenol results in decreased expression of ENO2 mRNA CTD PMID:15159206 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Epha8 Eph receptor A8 increases expression EXP nonylphenol results in increased expression of EPHA8 mRNA CTD PMID:17010207 NCBI chr 5:155,293,731...155,321,016
Ensembl chr 5:155,295,314...155,316,495
JBrowse link
G Ereg epiregulin increases expression EXP nonylphenol results in increased expression of EREG mRNA CTD PMID:17010207 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression EXP nonylphenol results in decreased expression of ERP29 protein CTD PMID:19260726 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G Esr1 estrogen receptor 1 affects activity
affects localization
increases expression
multiple interactions
decreases expression
increases activity
affects binding
ISO
EXP
nonylphenol affects the activity of ESR1 protein
nonylphenol affects the localization of ESR1 protein
nonylphenol results in increased expression of ESR1 mRNA
[nonylphenol binds to ESR1 protein] which results in increased activity of ALPL protein; [nonylphenol results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA; [nonylphenol results in increased activity of ESR1 protein] which results in increased expression of TFF1 mRNA; afimoxifene inhibits the reaction [nonylphenol results in increased activity of ESR1 protein]; ESR1 protein promotes the reaction [nonylphenol promotes the reaction [ESR1 protein binds to CTSD promoter]]; Fulvestrant inhibits the reaction [nonylphenol promotes the reaction [ESR1 protein binds to CTSD promoter]]; nonylphenol analog inhibits the reaction [Estradiol binds to ESR1 protein]; nonylphenol analog inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; nonylphenol binds to and results in increased activity of ESR1 protein; nonylphenol inhibits the reaction [Estradiol binds to ESR1 protein]; nonylphenol promotes the reaction [ESR1 protein binds to CTSD promoter]; nonylphenol results in increased activity of and results in increased localization of ESR1 protein; TGFB3 protein inhibits the reaction [nonylphenol results in increased expression of ESR1 mRNA]
nonylphenol analog results in increased expression of ESR1 mRNA; nonylphenol analog results in increased expression of ESR1 protein
nonylphenol analog results in decreased expression of ESR1 mRNA; nonylphenol analog results in decreased expression of ESR1 protein
nonylphenol results in increased expression of ESR1 mRNA; nonylphenol results in increased expression of ESR1 protein
nonylphenol analog results in increased activity of ESR1 protein; nonylphenol results in increased activity of ESR1 protein
nonylphenol results in decreased expression of ESR1 mRNA; nonylphenol results in decreased expression of ESR1 protein
nonylphenol analog binds to ESR1 protein; nonylphenol binds to ESR1 protein; nonylphenol metabolite binds to ESR1 protein
CTD PMID:9751507, PMID:10492897, PMID:11086226, PMID:11731036, PMID:12062901, PMID:12504345, PMID:12650720, PMID:14579009, PMID:14709801, PMID:14754635, PMID:14975756, PMID:16756374, PMID:18635651, PMID:19720131, PMID:20074635, PMID:20362049, PMID:20435135, PMID:22467034, PMID:22941308, PMID:25242005, PMID:26224478, PMID:27260121, PMID:27366082, PMID:28280777, PMID:29066353 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity
multiple interactions
affects binding
ISO nonylphenol results in increased activity of ESR2 protein
nonylphenol binds to and results in increased activity of ESR2 protein; Sodium Hypochlorite inhibits the reaction [nonylphenol binds to ESR2 protein]
CTD PMID:9751507, PMID:14709801, PMID:14723943, PMID:14754635, PMID:16756374 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrrb estrogen-related receptor beta increases expression ISO nonylphenol results in increased expression of ESRRB mRNA CTD PMID:31288075 NCBI chr 6:110,360,940...110,458,406
Ensembl chr 6:110,410,141...110,455,906
JBrowse link
G F2rl1 F2R like trypsin receptor 1 decreases expression EXP nonylphenol results in decreased expression of F2RL1 mRNA CTD PMID:15620428 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
increases expression
ISO TGFB3 protein inhibits the reaction [nonylphenol results in increased expression of FOS mRNA]
nonylphenol results in decreased expression of FOS mRNA
CTD PMID:26224478, PMID:32645552 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fshr follicle stimulating hormone receptor increases expression
decreases expression
ISO
EXP
nonylphenol analog results in increased expression of FSHR protein
nonylphenol results in decreased expression of FSHR protein
nonylphenol results in increased expression of FSHR mRNA
CTD PMID:25242005, PMID:27832966 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression EXP nonylphenol results in decreased expression of G6PD protein CTD PMID:19260726 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression EXP nonylphenol results in increased expression of GAD1 mRNA CTD PMID:15620428 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 decreases expression EXP nonylphenol results in decreased expression of GAD2 mRNA CTD PMID:15620428 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Galr1 galanin receptor 1 decreases expression EXP nonylphenol results in decreased expression of GALR1 mRNA CTD PMID:15620428 NCBI chr18:79,243,009...79,258,570
Ensembl chr18:79,243,009...79,258,570
JBrowse link
G Galr2 galanin receptor 2 decreases expression EXP nonylphenol results in decreased expression of GALR2 mRNA CTD PMID:15518916, PMID:15620428 NCBI chr10:105,156,793...105,159,221
Ensembl chr10:105,156,632...105,237,611
JBrowse link
G Gck glucokinase decreases expression EXP nonylphenol results in decreased expression of GCK mRNA CTD PMID:22946080 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gdi2 GDP dissociation inhibitor 2 increases expression EXP nonylphenol results in increased expression of GDI2 protein CTD PMID:19260726 NCBI chr17:70,299,177...70,325,864
Ensembl chr17:70,299,183...70,325,855
JBrowse link
G Ghrh growth hormone releasing hormone increases expression EXP nonylphenol results in increased expression of GHRH mRNA CTD PMID:17010207 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 decreases expression EXP nonylphenol results in decreased expression of GPD1 protein CTD PMID:19260726 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions
decreases expression
increases activity
ISO
EXP
nonylphenol binds to and results in increased activity of GPER1 protein
nonylphenol results in decreased expression of GPER1 mRNA
nonylphenol results in increased activity of GPER1 protein
CTD PMID:15620428, PMID:17088055, PMID:24604882 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Gpr1 G protein-coupled receptor 1 increases expression EXP nonylphenol results in increased expression of GPR1 mRNA CTD PMID:15620428 NCBI chr 9:69,958,607...69,991,410
Ensembl chr 9:69,959,025...69,960,086
JBrowse link
G Gpr19 G protein-coupled receptor 19 decreases expression EXP nonylphenol results in decreased expression of GPR19 mRNA CTD PMID:15620428 NCBI chr 4:168,639,930...168,668,345
Ensembl chr 4:168,639,940...168,656,673
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO nonylphenol results in decreased expression of GPX1 mRNA CTD PMID:32645552 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP nonylphenol results in increased expression of GPX4 mRNA CTD PMID:17679765 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression EXP nonylphenol results in decreased expression of GRIN1 mRNA CTD PMID:15518916 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grm1 glutamate metabotropic receptor 1 decreases expression EXP nonylphenol results in decreased expression of GRM1 mRNA CTD PMID:15620428 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Grm2 glutamate metabotropic receptor 2 decreases expression EXP nonylphenol results in decreased expression of GRM2 mRNA CTD PMID:15620428 NCBI chr 8:115,344,999...115,358,628
Ensembl chr 8:115,344,999...115,358,046
JBrowse link
G Grm6 glutamate metabotropic receptor 6 decreases expression EXP nonylphenol results in decreased expression of GRM6 mRNA CTD PMID:15620428 NCBI chr10:36,345,503...36,363,416
Ensembl chr10:36,345,939...36,360,665
JBrowse link
G Grpr gastrin releasing peptide receptor decreases expression EXP nonylphenol results in decreased expression of GRPR mRNA CTD PMID:15620428 NCBI chr  X:32,746,259...32,786,266
Ensembl chr  X:32,745,873...32,786,359
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO nonylphenol results in increased expression of GSTA2 protein CTD PMID:16054331 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP nonylphenol results in increased expression of HMOX1 protein CTD PMID:30481583 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1a HNF1 homeobox A decreases expression EXP nonylphenol results in decreased expression of HNF1A mRNA CTD PMID:22946080 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions EXP nonylphenol results in increased expression of and results in increased activity of HSD11B1 protein CTD PMID:22765982 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP nonylphenol results in decreased expression of HSD3B1 mRNA CTD PMID:17229994
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP nonylphenol results in increased expression of HSPA1A mRNA CTD PMID:17010207 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 affects expression
increases expression
EXP nonylphenol affects the expression of HSPA5 protein
nonylphenol results in increased expression of HSPA5 mRNA
CTD PMID:19429228 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression EXP nonylphenol results in decreased expression of HSPB1 protein CTD PMID:19260726 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F decreases expression EXP nonylphenol results in decreased expression of HTR1F mRNA CTD PMID:15620428 NCBI chr11:1,982,113...1,983,513
Ensembl chr11:1,982,113...1,983,513
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO nonylphenol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO nonylphenol results in decreased expression of IGFBP5 mRNA CTD PMID:15159206 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases expression EXP nonylphenol results in increased expression of IKBKB mRNA CTD PMID:17010207 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
ISO IL10 affects the reaction [nonylphenol results in increased expression of TNF]; nonylphenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL10]; nonylphenol results in decreased expression of and results in decreased secretion of IL10 protein
nonylphenol results in decreased expression of IL10
CTD PMID:20056579, PMID:24039973 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Fulvestrant inhibits the reaction [nonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]]; nonylphenol inhibits the reaction [IL1A protein promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to CCL2 promoter]]; nonylphenol inhibits the reaction [IL1A protein results in increased expression of CCL2 mRNA]; nonylphenol inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein] CTD PMID:10614622 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression ISO
EXP
nonylphenol results in increased expression of IL1B mRNA
nonylphenol results in increased expression of IL1B protein
CTD PMID:27260121, PMID:32240654 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 multiple interactions
increases expression
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [nonylphenol results in increased expression of IL4 protein]; Nitrendipine inhibits the reaction [nonylphenol results in increased expression of IL4 protein]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [NFATC3 protein binds to IL4 promoter]; Tacrolimus inhibits the reaction [nonylphenol promotes the reaction [NFATC3 protein binds to IL4 promoter]]; Tacrolimus inhibits the reaction [nonylphenol results in increased expression of IL4 protein]; Thapsigargin inhibits the reaction [nonylphenol results in increased expression of IL4 protein]
nonylphenol results in increased expression of IL4 mRNA; nonylphenol results in increased expression of IL4 protein
CTD PMID:12709020 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
nonylphenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
nonylphenol results in increased expression of IL6 protein
CTD PMID:28168795, PMID:32240654 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inha inhibin subunit alpha increases expression EXP nonylphenol results in increased expression of INHA mRNA CTD PMID:27832966 NCBI chr 9:82,700,482...82,703,383
Ensembl chr 9:82,700,468...82,703,400
JBrowse link
G Inhbb inhibin subunit beta B increases expression ISO nonylphenol analog results in increased expression of INHBB protein CTD PMID:25242005 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO nonylphenol results in decreased expression of JUN mRNA CTD PMID:32645552 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Klhl41 kelch-like family member 41 increases expression EXP nonylphenol results in increased expression of KLHL41 mRNA CTD PMID:17010207 NCBI chr 3:55,910,177...55,923,303
Ensembl chr 3:55,910,177...55,923,303
JBrowse link
G Kmt2a lysine methyltransferase 2A increases expression ISO nonylphenol results in increased expression of KMT2A protein CTD PMID:20056579 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP nonylphenol results in increased expression of LBP mRNA CTD PMID:17010207 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 increases expression EXP nonylphenol results in increased expression of LCP2 mRNA CTD PMID:17010207 NCBI chr10:18,996,523...19,043,289
Ensembl chr10:18,996,523...19,043,286
JBrowse link
G Ldha lactate dehydrogenase A increases expression EXP nonylphenol results in increased expression of LDHA mRNA CTD PMID:17010207 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Lep leptin increases expression ISO nonylphenol results in increased expression of LEP mRNA CTD PMID:18417718 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lgals3 galectin 3 increases expression ISO nonylphenol results in increased expression of LGALS3 protein CTD PMID:16054331 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Ltf lactotransferrin increases expression ISO nonylphenol results in increased expression of LTF protein CTD PMID:11390168 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha increases expression EXP nonylphenol results in increased expression of MAP1LC3A mRNA CTD PMID:27832966 NCBI chr 3:150,801,289...150,802,935
Ensembl chr 3:150,801,289...150,802,935
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases cleavage
affects expression
multiple interactions
EXP nonylphenol results in increased cleavage of MAP1LC3B protein
nonylphenol affects the expression of MAP1LC3B protein
Acetylcysteine inhibits the reaction [nonylphenol results in increased expression of MAP1LC3B protein]
CTD PMID:27832966 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression ISO nonylphenol results in increased expression of MAP2K3 protein CTD PMID:24039973 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 increases expression ISO nonylphenol results in increased expression of MAP2K6 protein CTD PMID:24039973 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
decreases phosphorylation
EXP
ISO
nonylphenol results in increased phosphorylation of MAPK1 protein
nonylphenol analog results in decreased phosphorylation of MAPK1 protein
CTD PMID:15531431, PMID:23677851, PMID:25242005 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
decreases phosphorylation
EXP
ISO
nonylphenol results in increased phosphorylation of MAPK3 protein
nonylphenol analog results in decreased phosphorylation of MAPK3 protein
CTD PMID:15531431, PMID:23677851, PMID:25242005 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression
multiple interactions
ISO nonylphenol results in increased expression of MKI67 mRNA
fulvestrant inhibits the reaction [nonylphenol results in increased expression of MKI67 mRNA]
CTD PMID:27260121 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [nonylphenol results in increased expression of MMP2 protein]; Genistein inhibits the reaction [nonylphenol results in increased expression of MMP2 protein] CTD PMID:26407941 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [nonylphenol results in increased expression of MMP9 protein] CTD PMID:25690688 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression
increases expression
decreases phosphorylation
EXP nonylphenol results in decreased expression of MTOR mRNA; nonylphenol results in decreased expression of MTOR protein; nonylphenol results in decreased expression of MTOR protein modified form
nonylphenol results in increased expression of MTOR protein modified form
nonylphenol results in decreased phosphorylation of MTOR protein
CTD PMID:27832966, PMID:29641977 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression EXP nonylphenol results in increased expression of MYD88 protein CTD PMID:30481583 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nanog Nanog homeobox increases expression ISO nonylphenol results in increased expression of NANOG mRNA CTD PMID:31288075 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO nonylphenol promotes the reaction [NCOA1 protein binds to CTSD promoter] CTD PMID:27366082 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 decreases expression ISO nonylphenol results in decreased expression of NDUFA1 mRNA CTD PMID:32645552 NCBI chr  X:123,803,109...123,806,760
Ensembl chr  X:124,513,269...124,516,705
Ensembl chr  X:124,513,269...124,516,705
JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression ISO nonylphenol results in decreased expression of NDUFB6 mRNA CTD PMID:32645552 NCBI chr 5:56,567,109...56,576,676
Ensembl chr 5:56,567,109...56,576,676
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 multiple interactions ISO nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [NFATC3 protein binds to IL4 promoter]; Tacrolimus inhibits the reaction [nonylphenol promotes the reaction [NFATC3 protein binds to IL4 promoter]] CTD PMID:12709020 NCBI chr19:38,039,542...38,114,003
Ensembl chr19:38,039,564...38,114,003
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression EXP nonylphenol results in increased expression of NFE2L2 protein CTD PMID:30481583 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO nonylphenol inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]
nonylphenol inhibits the reaction [IL1A protein promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to CCL2 promoter]]
CTD PMID:10614622, PMID:17015962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nit1 nitrilase 1 decreases expression EXP nonylphenol results in decreased expression of NIT1 protein CTD PMID:19260726 NCBI chr13:89,722,370...89,725,806
Ensembl chr13:89,722,374...89,725,806
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP nonylphenol results in increased expression of NME2 protein CTD PMID:19260726 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Nme7 NME/NM23 family member 7 increases expression EXP nonylphenol results in increased expression of NME7 mRNA CTD PMID:17010207 NCBI chr13:82,607,844...82,737,383
Ensembl chr13:82,626,685...82,737,343
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO
EXP
nonylphenol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
nonylphenol results in increased expression of NOS2 protein
CTD PMID:28168795, PMID:30481583 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects response to substance
multiple interactions
increases response to substance
ISO
EXP
NR1I2 protein affects the susceptibility to nonylphenol
nonylphenol binds to and results in increased activity of NR1I2 protein
NR1I2 protein results in increased susceptibility to nonylphenol
CTD PMID:14613717, PMID:16054614, PMID:21376070 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO nonylphenol affects the reaction [NR1I3 affects the susceptibility to Zoxazolamine]; nonylphenol binds to and results in increased activity of NR1I3 protein; nonylphenol inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; NR1I3 affects the reaction [nonylphenol results in decreased expression of CYP2C40 mRNA]; NR1I3 gene mutant form affects the reaction [nonylphenol results in increased expression of CYP2B10 mRNA]; NR1I3 gene mutant form affects the reaction [nonylphenol results in increased expression of CYP2C29 mRNA]; NR1I3 gene mutant form affects the reaction [nonylphenol results in increased expression of CYP3A11 mRNA] CTD PMID:18832183, PMID:19041682 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Oat ornithine aminotransferase decreases expression EXP nonylphenol results in decreased expression of OAT protein CTD PMID:19260726 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Ogdh oxoglutarate dehydrogenase decreases expression EXP nonylphenol results in decreased expression of OGDH mRNA CTD PMID:22946080 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Oprd1 opioid receptor, delta 1 decreases expression EXP nonylphenol results in decreased expression of OPRD1 mRNA CTD PMID:15620428 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 decreases expression EXP nonylphenol results in decreased expression of OPRL1 mRNA CTD PMID:15620428 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Oprm1 opioid receptor, mu 1 increases expression EXP nonylphenol results in increased expression of OPRM1 mRNA CTD PMID:15620428 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Oprpn opiorphin prepropeptide increases expression EXP nonylphenol results in increased expression of SMR2 mRNA CTD PMID:17010207 NCBI chr14:21,338,464...21,353,533
Ensembl chr14:21,338,601...21,352,491
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide increases expression EXP nonylphenol results in increased expression of OXT mRNA CTD PMID:17010207 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G P2rx2 purinergic receptor P2X 2 decreases expression EXP nonylphenol results in decreased expression of P2RX2 mRNA CTD PMID:15620428 NCBI chr12:52,397,666...52,401,005
Ensembl chr12:52,397,792...52,401,015
JBrowse link
G P2ry1 purinergic receptor P2Y1 decreases expression EXP nonylphenol results in decreased expression of P2RY1 mRNA CTD PMID:15620428 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO nonylphenol results in increased cleavage of PARP1 protein
U 0126 inhibits the reaction [nonylphenol results in increased cleavage of PARP1 protein]
CTD PMID:23677851 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression EXP nonylphenol results in decreased expression of PDGFRB mRNA CTD PMID:15518916 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression
increases expression
EXP nonylphenol affects the expression of PDIA3 protein
nonylphenol results in increased expression of PDIA3 protein
CTD PMID:19260726, PMID:19429228 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression EXP nonylphenol results in decreased expression of PDK1 mRNA CTD PMID:27832966 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 decreases expression EXP nonylphenol results in decreased expression of PDX1 mRNA CTD PMID:22946080 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression EXP nonylphenol results in increased expression of PEBP1 protein CTD PMID:19260726 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 increases expression EXP nonylphenol results in increased expression of PFKFB4 mRNA CTD PMID:17010207 NCBI chr 8:117,733,347...117,776,525
Ensembl chr 8:117,737,117...117,775,386
JBrowse link
G Pgr progesterone receptor affects binding
increases expression
decreases activity
multiple interactions
ISO
EXP
nonylphenol binds to PGR protein
nonylphenol analog results in increased expression of PGR mRNA
nonylphenol results in increased expression of PGR mRNA
nonylphenol results in increased expression of PGR mRNA; nonylphenol results in increased expression of PGR protein
nonylphenol results in decreased activity of PGR protein
nonylphenol inhibits the reaction [Progesterone binds to PGR protein]; nonylphenol inhibits the reaction [Progesterone results in increased expression of PGR protein]
CTD PMID:14579009, PMID:14763995, PMID:17304841, PMID:18262749, PMID:20172022, PMID:25242005 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma decreases expression
increases expression
EXP nonylphenol results in decreased expression of PIK3CG mRNA
nonylphenol results in increased expression of PIK3CG mRNA
CTD PMID:27832966 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression
multiple interactions
EXP nonylphenol results in decreased expression of PIK3R1 protein
wortmannin inhibits the reaction [nonylphenol results in decreased expression of PIK3R1 protein]
CTD PMID:27832966 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pitpna phosphatidylinositol transfer protein, alpha decreases expression EXP nonylphenol results in decreased expression of PITPNA protein CTD PMID:19260726 NCBI chr10:63,731,767...63,772,049
Ensembl chr10:63,731,767...63,772,049
JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases expression
EXP Fulvestrant inhibits the reaction [nonylphenol promotes the reaction [POMC protein modified form results in increased secretion of Corticosterone]]; nonylphenol inhibits the reaction [Nitroprusside inhibits the reaction [POMC protein modified form results in increased secretion of Corticosterone]]; nonylphenol promotes the reaction [POMC protein modified form results in increased secretion of Corticosterone]
nonylphenol results in increased expression of POMC protein
CTD PMID:20837582, PMID:22765982 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO nonylphenol results in increased expression of POU5F1 mRNA CTD PMID:31288075 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression EXP nonylphenol results in decreased expression of PPARG protein CTD PMID:29641977 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression EXP nonylphenol results in decreased expression of PPP1CB protein CTD PMID:19260726 NCBI chr 6:23,548,507...23,581,136
Ensembl chr 6:23,549,317...23,581,052
JBrowse link
G Prdm14 PR/SET domain 14 increases expression ISO nonylphenol results in increased expression of PRDM14 mRNA CTD PMID:31288075 NCBI chr 5:5,710,076...5,730,560
Ensembl chr 5:5,710,392...5,730,560
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO nonylphenol results in increased expression of PRDX1 protein CTD PMID:16054331 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prdx4 peroxiredoxin 4 decreases expression EXP nonylphenol results in decreased expression of PRDX4 protein CTD PMID:19260726 NCBI chr  X:43,495,453...43,512,994
Ensembl chr  X:43,497,763...43,512,991
JBrowse link
G Prdx6 peroxiredoxin 6 increases expression
decreases expression
EXP nonylphenol results in increased expression of PRDX6 protein
nonylphenol results in decreased expression of PRDX6 protein
CTD PMID:19260726 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases expression EXP nonylphenol results in decreased expression of PRKAA1 protein CTD PMID:29641977 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prl prolactin multiple interactions
increases secretion
EXP Nifedipine inhibits the reaction [nonylphenol results in increased secretion of PRL protein] CTD PMID:15811834, PMID:19479013 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Prlhr prolactin releasing hormone receptor increases expression EXP nonylphenol results in increased expression of PRLHR mRNA CTD PMID:15620428 NCBI chr 1:281,754,472...281,756,159
Ensembl chr 1:281,754,724...281,756,159
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 decreases expression EXP nonylphenol results in decreased expression of PSMA1 protein CTD PMID:19260726 NCBI chr 1:183,733,567...183,744,586
Ensembl chr 1:183,733,567...183,744,586
JBrowse link
G Psma2 proteasome 20S subunit alpha 2 increases expression EXP nonylphenol results in increased expression of PSMA2 protein CTD PMID:19260726 NCBI chr17:53,091,937...53,102,324
Ensembl chr17:53,091,933...53,102,342
JBrowse link
G Psmb4 proteasome 20S subunit beta 4 decreases expression EXP nonylphenol results in decreased expression of PSMB4 protein CTD PMID:19260726 NCBI chr 2:196,043,546...196,046,320
Ensembl chr 2:196,043,618...196,046,311
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 decreases expression EXP nonylphenol results in decreased expression of PSMC2 protein CTD PMID:19260726 NCBI chr 4:9,867,132...9,881,383
Ensembl chr 4:9,867,101...9,881,484
JBrowse link
G Pten phosphatase and tensin homolog increases expression
multiple interactions
decreases expression
EXP nonylphenol results in increased expression of PTEN mRNA
wortmannin inhibits the reaction [nonylphenol results in decreased expression of PTEN protein]
CTD PMID:27832966 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgdr prostaglandin D2 receptor increases expression EXP nonylphenol results in increased expression of PTGDR mRNA CTD PMID:15620428 NCBI chr15:19,195,606...19,196,508 JBrowse link
G Ptger2 prostaglandin E receptor 2 decreases expression EXP nonylphenol results in decreased expression of PTGER2 mRNA CTD PMID:15620428 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression EXP nonylphenol results in decreased expression of PTGER4 mRNA CTD PMID:15620428 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptgfr prostaglandin F receptor decreases expression EXP nonylphenol results in decreased expression of PTGFR mRNA CTD PMID:15620428 NCBI chr 2:257,005,813...257,039,036
Ensembl chr 2:257,005,829...257,038,105
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nonylphenol results in increased expression of PTGS2 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [nonylphenol results in increased expression of PTGS2 protein]; [nonylphenol results in increased expression of and results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone; nonylphenol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; nonylphenol results in increased expression of and results in increased activity of PTGS2 protein; SB 203580 inhibits the reaction [nonylphenol results in increased expression of PTGS2 protein]
nonylphenol results in increased expression of PTGS2 mRNA
CTD PMID:20954072, PMID:28168795, PMID:30481583, PMID:30629985 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rab14 RAB14, member RAS oncogene family increases expression EXP nonylphenol results in increased expression of RAB14 mRNA CTD PMID:17010207 NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
JBrowse link
G Rarb retinoic acid receptor, beta decreases expression ISO nonylphenol results in decreased expression of RARB mRNA CTD PMID:31288075 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
nonylphenol inhibits the reaction [IL1A protein promotes the reaction [[RELA protein binds to NFKB1 protein] which binds to CCL2 promoter]]
nonylphenol results in increased phosphorylation of and affects the localization of RELA protein
CTD PMID:10614622, PMID:30481583 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Retn resistin increases expression ISO nonylphenol results in increased expression of RETN mRNA CTD PMID:18417718 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Rheb Ras homolog, mTORC1 binding increases expression EXP nonylphenol results in increased expression of RHEB mRNA CTD PMID:27832966 NCBI chr 4:6,827,429...6,873,384
Ensembl chr 4:6,827,429...6,873,383
JBrowse link
G Rph3a rabphilin 3A increases expression EXP nonylphenol results in increased expression of RPH3A mRNA CTD PMID:17010207 NCBI chr12:41,073,296...41,149,799
Ensembl chr12:41,073,824...41,148,490
JBrowse link
G Rpn2 ribophorin II increases expression EXP nonylphenol results in increased expression of RPN2 mRNA CTD PMID:17010207 NCBI chr 3:153,398,373...153,445,633
Ensembl chr 3:153,398,130...153,445,632
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases expression
increases expression
EXP nonylphenol results in decreased expression of RPS6KB1 mRNA
nonylphenol results in increased expression of RPS6KB1 mRNA
CTD PMID:27832966 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression EXP nonylphenol results in increased expression of S100A6 mRNA CTD PMID:17010207 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G S100g S100 calcium binding protein G multiple interactions
increases expression
decreases expression
ISO
EXP
fulvestrant inhibits the reaction [nonylphenol results in increased expression of S100G mRNA]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of S100G protein]; Mifepristone inhibits the reaction [nonylphenol results in increased expression of S100G mRNA]; Mifepristone inhibits the reaction [nonylphenol results in increased expression of S100G protein]
nonylphenol results in increased expression of S100G mRNA; nonylphenol results in increased expression of S100G protein
nonylphenol results in decreased expression of S100G mRNA
CTD PMID:12062901, PMID:12759100, PMID:14654251, PMID:15070829, PMID:15219628, PMID:15509668, PMID:17010207, PMID:17504770 NCBI chr  X:33,442,820...33,445,714
Ensembl chr  X:33,443,186...33,445,709
JBrowse link
G Sctr secretin receptor decreases expression EXP nonylphenol results in decreased expression of SCTR mRNA CTD PMID:15620428 NCBI chr13:36,039,241...36,090,515
Ensembl chr13:36,039,283...36,090,530
JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression ISO nonylphenol results in decreased expression of SELENBP1 mRNA CTD PMID:15159206 NCBI chr 2:196,105,592...196,146,474
Ensembl chr 2:196,105,569...196,113,149
JBrowse link
G Shbg sex hormone binding globulin multiple interactions
decreases expression
increases expression
ISO
EXP
nonylphenol inhibits the reaction [Dihydrotestosterone binds to SHBG protein]
nonylphenol results in decreased expression of SHBG protein
nonylphenol results in increased expression of SHBG mRNA
wortmannin inhibits the reaction [nonylphenol results in increased expression of SHBG mRNA]
CTD PMID:9171990, PMID:27832966 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Skil SKI-like proto-oncogene multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [nonylphenol results in increased expression of SKIL protein]; Genistein inhibits the reaction [nonylphenol results in increased expression of SKIL protein] CTD PMID:26407941 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
G Slc12a2 solute carrier family 12 member 2 decreases expression ISO nonylphenol results in decreased expression of SLC12A2 mRNA CTD PMID:15159206 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression EXP nonylphenol results in increased expression of SLC1A5 mRNA CTD PMID:17010207 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases expression EXP nonylphenol results in increased expression of SLC22A6 mRNA CTD PMID:17010207 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP nonylphenol results in decreased expression of SLC2A2 mRNA; nonylphenol results in decreased expression of SLC2A2 protein CTD PMID:21472897, PMID:22946080 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions EXP nonylphenol affects the reaction [SLC6A3 protein affects the export of Dopamine] CTD PMID:19479021 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO nonylphenol results in increased expression of SLC7A11 mRNA CTD PMID:15159206 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slfn3 schlafen family member 3 increases expression EXP nonylphenol results in increased expression of SLFN3 mRNA CTD PMID:17010207 NCBI chr10:70,438,012...70,477,259 JBrowse link
G Smad3 SMAD family member 3 decreases phosphorylation
multiple interactions
ISO nonylphenol results in decreased phosphorylation of SMAD3 protein
fulvestrant inhibits the reaction [nonylphenol results in decreased phosphorylation of SMAD3 protein]; Genistein inhibits the reaction [nonylphenol results in decreased phosphorylation of SMAD3 protein]
CTD PMID:26407941 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [nonylphenol results in increased expression of SNAI1 mRNA]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of SNAI1 protein]
nonylphenol results in increased expression of SNAI1 mRNA; nonylphenol results in increased expression of SNAI1 protein
CTD PMID:25690688 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression
multiple interactions
ISO nonylphenol results in increased expression of SNAI2 mRNA
fulvestrant inhibits the reaction [nonylphenol results in increased expression of SNAI2 mRNA]
CTD PMID:25690688 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Snap25 synaptosome associated protein 25 decreases expression EXP nonylphenol results in decreased expression of SNAP25 mRNA CTD PMID:22946080 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400
JBrowse link
G Sox2 SRY-box transcription factor 2 increases expression ISO nonylphenol results in increased expression of SOX2 mRNA CTD PMID:31288075 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
increases expression
EXP nonylphenol affects the reaction [CGA protein results in increased expression of STAR protein]
nonylphenol analog results in decreased expression of STAR mRNA
nonylphenol results in increased expression of STAR protein
CTD PMID:19883722, PMID:22765982, PMID:22771390 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stk17b serine/threonine kinase 17b increases expression EXP nonylphenol results in increased expression of STK17B mRNA CTD PMID:17010207 NCBI chr 9:60,399,261...60,430,081
Ensembl chr 9:60,399,261...60,430,081
JBrowse link
G Stra8 stimulated by retinoic acid 8 increases expression ISO nonylphenol results in increased expression of STRA8 mRNA CTD PMID:31288075 NCBI chr 4:62,447,724...62,474,802
Ensembl chr 4:62,457,694...62,473,360
JBrowse link
G Tacr2 tachykinin receptor 2 decreases expression EXP nonylphenol results in decreased expression of TACR2 mRNA CTD PMID:15620428 NCBI chr20:31,892,515...31,905,153
Ensembl chr20:31,892,515...31,905,153
JBrowse link
G Tardbp TAR DNA binding protein decreases expression EXP nonylphenol results in decreased expression of TARDBP protein CTD PMID:19260726 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tcp1 t-complex 1 increases expression EXP nonylphenol results in increased expression of TCP1 protein CTD PMID:19260726 NCBI chr 1:48,025,664...48,033,343
Ensembl chr 1:48,025,663...48,033,396
JBrowse link
G Tf transferrin affects expression
decreases expression
EXP nonylphenol affects the expression of TF mRNA
nonylphenol results in decreased expression of TF protein
CTD PMID:27832966 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO [nonylphenol results in increased activity of ESR1 protein] which results in increased expression of TFF1 mRNA
nonylphenol results in increased expression of TFF1 mRNA
CTD PMID:14709801, PMID:14754635 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions ISO TGFB3 protein inhibits the reaction [nonylphenol results in increased expression of ESR1 mRNA]; TGFB3 protein inhibits the reaction [nonylphenol results in increased expression of FOS mRNA] CTD PMID:26224478 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP nonylphenol results in decreased expression of TJP1 protein CTD PMID:32240654 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression
increases expression
ISO
EXP
nonylphenol analog results in decreased expression of TLR4 mRNA
nonylphenol results in increased expression of TLR4 protein
CTD PMID:25242005, PMID:30481583 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nonylphenol results in increased expression of and results in increased secretion of TNF protein]; anacardic acid inhibits the reaction [nonylphenol results in increased expression of and results in increased secretion of TNF protein]; anacardic acid inhibits the reaction [nonylphenol results in increased expression of TNF]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of and results in increased secretion of TNF protein]; Fulvestrant inhibits the reaction [nonylphenol results in increased expression of TNF]; IL10 affects the reaction [nonylphenol results in increased expression of TNF]; nonylphenol results in increased expression of and results in increased secretion of TNF protein; SB 203580 inhibits the reaction [nonylphenol results in increased expression of and results in increased secretion of TNF protein]; SB 203580 inhibits the reaction [nonylphenol results in increased expression of TNF]
nonylphenol results in increased expression of TNF protein
nonylphenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
nonylphenol results in increased secretion of TNF protein
nonylphenol results in increased expression of TNF; nonylphenol results in increased expression of TNF mRNA
CTD PMID:20056579, PMID:24039973, PMID:28168795, PMID:32240654 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tor1a torsin family 1, member A decreases expression EXP nonylphenol results in decreased expression of TOR1A protein CTD PMID:19260726 NCBI chr 3:9,800,322...9,807,318
Ensembl chr 3:9,800,322...9,807,328
JBrowse link
G Traf6 TNF receptor associated factor 6 increases expression EXP nonylphenol results in increased expression of TRAF6 protein CTD PMID:30481583 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Tsc1 TSC complex subunit 1 decreases expression EXP nonylphenol results in decreased expression of TSC1 protein CTD PMID:29641977 NCBI chr 3:7,219,955...7,269,063
Ensembl chr 3:7,237,192...7,265,145
JBrowse link
G Tsc2 TSC complex subunit 2 affects expression
decreases expression
EXP nonylphenol affects the expression of TSC2 mRNA
nonylphenol results in decreased expression of TSC2 protein
CTD PMID:27832966, PMID:29641977 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression EXP nonylphenol results in decreased expression of TSHR mRNA CTD PMID:15620428 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link
G Ttr transthyretin affects binding ISO nonylphenol binds to TTR protein CTD PMID:29427707 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Tubb6 tubulin, beta 6 class V decreases expression EXP nonylphenol results in decreased expression of TUBB6 protein CTD PMID:19260726 NCBI chr18:63,130,542...63,140,181
Ensembl chr18:63,130,542...63,140,181
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial increases expression EXP nonylphenol results in increased expression of TUFM protein CTD PMID:19260726 NCBI chr 1:197,903,582...197,907,189
Ensembl chr 1:197,903,582...197,907,189
JBrowse link
G Ucp2 uncoupling protein 2 increases expression
decreases expression
EXP
ISO
nonylphenol results in increased expression of UCP2 mRNA
nonylphenol results in decreased expression of UCP2 mRNA
CTD PMID:22946080, PMID:32645552 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases glucuronidation EXP UGT2B1 protein results in increased glucuronidation of nonylphenol CTD PMID:11836149 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vcl vinculin decreases expression ISO nonylphenol analog results in decreased expression of VCL mRNA CTD PMID:25242005 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO nonylphenol results in decreased expression of VEGFA protein CTD PMID:23672405 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin increases expression
decreases expression
multiple interactions
ISO
EXP
nonylphenol analog results in increased expression of VIM mRNA
nonylphenol results in decreased expression of VIM protein
nonylphenol results in increased expression of VIM mRNA; nonylphenol results in increased expression of VIM protein
fulvestrant inhibits the reaction [nonylphenol results in increased expression of VIM mRNA]; fulvestrant inhibits the reaction [nonylphenol results in increased expression of VIM protein]
CTD PMID:25242005, PMID:25690688, PMID:26407941, PMID:27832966 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO nonylphenol results in increased expression of WARS1 mRNA CTD PMID:15159206 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Wdr1 WD repeat domain 1 increases expression EXP nonylphenol results in increased expression of WDR1 protein CTD PMID:19260726 NCBI chr14:76,990,014...77,023,739
Ensembl chr14:76,989,919...77,023,726
JBrowse link
G Wdr5 WD repeat domain 5 increases expression ISO nonylphenol results in increased expression of WDR5 protein CTD PMID:20056579 NCBI chr 3:6,061,892...6,080,724
Ensembl chr 3:6,061,940...6,080,680
JBrowse link
G Zfp42 zinc finger protein 42 increases expression ISO nonylphenol results in increased expression of ZFP42 mRNA CTD PMID:31288075 NCBI chr16:52,016,590...52,026,346 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Nonylphenol 250
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Nonylphenol 250
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.