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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:penciclovir
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Accession:CHEBI:7956 term browser browse the term
Definition:A member of the class of 2-aminopurines that is guanine in which the hydrogen at position 9 is substituted by a 4-hydroxy-3-(hydroxymethyl)but-1-yl group. An antiviral drug, it is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration.
Synonyms:related_synonym: 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one;   9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine;   9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine;   9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine;   9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine;   Formula=C10H15N5O3;   InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18);   InChIKey=JNTOCHDNEULJHD-UHFFFAOYSA-N;   PCV;   PE2;   SMILES=Nc1nc2n(CCC(CO)CO)cnc2c(=O)[nH]1;   penciclovirum
 alt_id: CHEBI:44870
 xref: CAS:39809-25-1;   DrugBank:DB00299;   Drug_Central:2079;   HMDB:HMDB0014444;   KEGG:C07417;   KEGG:D05407;   LINCS:LSM-5587;   PDBeChem:PE2;   PMID:3040998;   Patent:US5075445;   Reaxys:4501039;   Wikipedia:Penciclovir


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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        antimicrobial agent 17329
          antiviral agent 10253
            antiviral drug 1834
              penciclovir 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  organic heteropolycyclic compound 17838
                                    organic heterobicyclic compound 16763
                                      imidazopyrimidine 5444
                                        purines 5442
                                          aminopurine 4399
                                            2-aminopurines 4009
                                              guanine 3973
                                                penciclovir 0
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