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ONTOLOGY REPORT - ANNOTATIONS


Term:10-Hydroxycamptothecin
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Accession:CHEBI:81395 term browser browse the term
Definition:A pyranoindolizinoquinoline that has formula C20H16N2O5.
Synonyms:related_synonym: Formula=C20H16N2O5;   InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1;   InChIKey=HAWSQZCWOQZXHI-FQEVSTJZSA-N;   SMILES=CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O
 xref: CAS:19685-09-7 "KEGG COMPOUND";   KEGG:C17939;   LINCS:LSM-4685
 xref_mesh: MESH:C028098


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10-Hydroxycamptothecin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    chemical entity 19732
      atom 19730
        nonmetal atom 19601
          nitrogen atom 18402
            nitrogen molecular entity 18402
              organonitrogen compound 18191
                organonitrogen heterocyclic compound 17193
                  pyranoindolizinoquinoline 3211
                    10-Hydroxycamptothecin 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic molecule 19418
                              organic cyclic compound 19189
                                organic heterocyclic compound 18267
                                  organic heteropolycyclic compound 17572
                                    organic heteropentacyclic compound 13167
                                      pyranoindolizinoquinoline 3211
                                        10-Hydroxycamptothecin 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.