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ONTOLOGY REPORT - ANNOTATIONS


Term:2-hydroxy-5-methylquinone
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Accession:CHEBI:81667 term browser browse the term
Definition:A member of the class of monohydroxy-1,4-benzoquinones that is 2-hydroxy-1,4-benzoquinone carrying an additional methyl substituent at position 5.
Synonyms:exact_synonym: 2-hydroxy-5-methylcyclohexa-2,5-diene-1,4-dione
 related_synonym: 2-Hydroxy-5-methyl-1,4-benzoquinone;   2-Hydroxy-5-methyl-p-benzoquinone;   Formula=C7H6O3;   InChI=1S/C7H6O3/c1-4-2-6(9)7(10)3-5(4)8/h2-3,10H,1H3;   InChIKey=BMBZVGUSOUAIMK-UHFFFAOYSA-N;   SMILES=C=1C(C(=CC(C1C)=O)O)=O
 xref: CAS:615-91-8 "ChemIDplus";   CAS:615-91-8 "KEGG COMPOUND";   KEGG:C18316;   MetaCyc:CPD-9135;   Reaxys:1861302 "Reaxys"
 cyclic_relationship: is_conjugate_acid_of CHEBI:88190


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coenzyme Q10 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G APP amyloid beta precursor protein JBrowse link 21 25,880,550 26,171,128 RGD:6480464
G ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 JBrowse link 4 36,005,186 36,244,833 RGD:6480464
G BAD BCL2 associated agonist of cell death JBrowse link 11 64,269,828 64,284,704 RGD:6480464
G BAK1 BCL2 antagonist/killer 1 JBrowse link 6 33,572,552 33,580,296 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BCL2L1 BCL2 like 1 JBrowse link 20 31,664,452 31,723,963 RGD:6480464
G C1QA complement C1q A chain JBrowse link 1 22,636,628 22,639,682 RGD:6480464
G C4B complement C4B (Chido blood group) JBrowse link 6 32,014,795 32,035,418 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP8 caspase 8 JBrowse link 2 201,233,443 201,287,711 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CCN2 cellular communication network factor 2 JBrowse link 6 131,948,176 131,951,372 RGD:6480464
G COL1A1 collagen type I alpha 1 chain JBrowse link 17 50,184,096 50,201,649 RGD:6480464
G CTSS cathepsin S JBrowse link 1 150,730,188 150,765,778 RGD:6480464
G EDN1 endothelin 1 JBrowse link 6 12,256,463 12,297,194 RGD:6480464
G EPS15 epidermal growth factor receptor pathway substrate 15 JBrowse link 1 51,354,263 51,519,275 RGD:6480464
G ETV3 ETS variant transcription factor 3 JBrowse link 1 157,121,191 157,138,591 RGD:6480464
G FADD Fas associated via death domain JBrowse link 11 70,203,296 70,207,390 RGD:6480464
G FASLG Fas ligand JBrowse link 1 172,659,008 172,666,876 RGD:6480464
G GFAP glial fibrillary acidic protein JBrowse link 17 44,903,159 44,915,552 RGD:6480464
G GPT glutamic--pyruvic transaminase JBrowse link 8 144,502,217 144,507,174 RGD:6480464
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 119,821,321 120,095,823 RGD:6480464
G GSR glutathione-disulfide reductase JBrowse link 8 30,678,061 30,727,999 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G KCNJ6 potassium inwardly rectifying channel subfamily J member 6 JBrowse link 21 37,607,373 37,916,457 RGD:6480464
G MMP2 matrix metallopeptidase 2 JBrowse link 16 55,478,830 55,506,691 RGD:6480464
G MMP9 matrix metallopeptidase 9 JBrowse link 20 46,008,908 46,016,561 RGD:6480464
G NCOA2 nuclear receptor coactivator 2 JBrowse link 8 70,109,770 70,405,390 RGD:6480464
G NDUFB6 NADH:ubiquinone oxidoreductase subunit B6 JBrowse link 9 32,553,001 32,573,184 RGD:6480464
G NDUFS7 NADH:ubiquinone oxidoreductase core subunit S7 JBrowse link 19 1,383,904 1,395,584 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6480464
G NOS3 nitric oxide synthase 3 JBrowse link 7 150,991,017 151,014,588 RGD:6480464
G PAH phenylalanine hydroxylase JBrowse link 12 102,836,889 102,958,441 RGD:6480464
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 5 68,215,737 68,301,821 RGD:6480464
G POU2F1 POU class 2 homeobox 1 JBrowse link 1 167,220,878 167,427,345 RGD:6480464
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma JBrowse link 14 101,760,573 101,927,992 RGD:6480464
G PSD3 pleckstrin and Sec7 domain containing 3 JBrowse link 8 18,527,303 19,086,909 RGD:6480464
G SKAP2 src kinase associated phosphoprotein 2 JBrowse link 7 26,654,772 26,864,623 RGD:6480464
G SMAD3 SMAD family member 3 JBrowse link 15 67,065,602 67,195,195 RGD:6480464
G SNCA synuclein alpha JBrowse link 4 89,724,099 89,838,324 RGD:6480464
G SOD2 superoxide dismutase 2 JBrowse link 6 159,669,069 159,762,281 RGD:6480464
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464
ubiquinone-1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 6 2,999,816 3,019,876 RGD:6480464
ubiquinone-9 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KCNJ6 potassium inwardly rectifying channel subfamily J member 6 JBrowse link 21 37,607,373 37,916,457 RGD:6480464
ubiquinones term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALAD aminolevulinate dehydratase JBrowse link 9 113,386,312 113,401,338 RGD:6480464
G ALDH2 aldehyde dehydrogenase 2 family member JBrowse link 12 111,766,933 111,817,532 RGD:15036805
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G COQ8A coenzyme Q8A JBrowse link 1 226,939,339 226,987,544 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 73,740,569 73,743,716 RGD:6480464
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 16 72,008,744 72,027,659 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G NOS3 nitric oxide synthase 3 JBrowse link 7 150,991,017 151,014,588 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PPARA peroxisome proliferator activated receptor alpha JBrowse link 22 46,150,526 46,243,756 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23754
    chemical entity 23717
      molecular entity 23664
        polyatomic entity 23570
          heteroatomic molecular entity 23134
            hydroxides 21980
              organic hydroxy compound 20338
                enol 692
                  monohydroxy-1,4-benzoquinones 65
                    2-hydroxy-5-methylquinone 58
                      2,3-dihydroxy-5-methyl-1,4-benzoquinone + 58
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  main group element atom 23522
                    p-block element atom 23522
                      carbon group element atom 23232
                        carbon atom 23208
                          organic molecular entity 23208
                            organic group 21897
                              organic divalent group 21869
                                organodiyl group 21869
                                  carbonyl group 21840
                                    carbonyl compound 21840
                                      ketone 18003
                                        cyclic ketone 14405
                                          quinone 8825
                                            benzoquinones 604
                                              1,4-benzoquinones 600
                                                monohydroxy-1,4-benzoquinones 65
                                                  2-hydroxy-5-methylquinone 58
                                                    2,3-dihydroxy-5-methyl-1,4-benzoquinone + 58
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.