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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:81843 term browser browse the term
Definition:A member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens.
Synonyms:exact_synonym: 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine
 related_synonym: 3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-alpha,alpha,alpha-trifluoro-2,6-dinitro-p-toluidine;   Formula=C13H4Cl2F6N4O4;   InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23);   InChIKey=UZCGKGPEKUCDTF-UHFFFAOYSA-N;   SMILES=[O-][N+](=O)c1cc(c(Cl)c(c1Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F;   Shirlan
 xref: CAS:79622-59-6;   KEGG:C18578
 xref_mesh: MESH:C075780
 xref: PMID:19837458;   PMID:21907236;   PMID:22465686;   PMID:23464902;   PMID:24427089;   PMID:24813983;   PMID:7774188;   PPDB:325;   Patent:NZ582589;   Patent:WO2011092618;   Pesticides:fluazinam;   Reaxys:4772672;   Wikipedia:Fluazinam

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fluazinam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO fluazinam results in increased expression of BAX protein CTD PMID:21907236 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO fluazinam results in decreased expression of BCL2 protein CTD PMID:21907236 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases activity ISO fluazinam results in increased activity of CASP3 protein CTD PMID:21907236 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO fluazinam results in decreased activity of DIO1 protein CTD PMID:29228274, PMID:30561685 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO fluazinam results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO fluazinam results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO fluazinam results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Tp53 tumor protein p53 increases expression ISO fluazinam results in increased expression of TP53 protein CTD PMID:21907236 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

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  CHEBI ontology 19816
    role 19764
      biological role 19764
        xenobiotic 18413
          fluazinam 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    main group molecular entity 19702
                      s-block molecular entity 19461
                        hydrogen molecular entity 19452
                          hydrides 18707
                            organic hydride 18269
                              organic fundamental parent 18269
                                hydrocarbon 17988
                                  halohydrocarbon 13956
                                    haloalkane 11674
                                      fluoroalkane 7118
                                        fluoromethanes 6335
                                          tetrafluoromethane 6335
                                            trifluoromethyl group 6335
                                              (trifluoromethyl)benzenes 6335
                                                fluazinam 8
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