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ONTOLOGY REPORT - ANNOTATIONS


Term:pimozide
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Accession:CHEBI:8212 term browser browse the term
Definition:A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which one of the nitrogens is substituted by a piperidin-4-yl group, which in turn is substituted on the nitrogen by a 4,4-bis(p-fluorophenyl)butyl group.
Synonyms:exact_synonym: 1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
 related_synonym: Formula=C28H29F2N3O;   Halomonth;   InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34);   InChIKey=YVUQSNJEYSNKRX-UHFFFAOYSA-N;   Neoperidole;   Opiran;   Orap;   SMILES=Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1;   pimozida;   pimozidum
 xref: Beilstein:729089 "Beilstein";   CAS:2062-78-4 "ChemIDplus";   CAS:2062-78-4 "KEGG COMPOUND";   CAS:2062-78-4 "NIST Chemistry WebBook";   DrugBank:DB01100;   Drug_Central:2172 "DrugCentral";   HMDB:HMDB0015232;   KEGG:C07566;   KEGG:D00560;   LINCS:LSM-2001
 xref_mesh: MESH:D010868
 xref: Reaxys:729089 "Reaxys";   Wikipedia:Pimozide


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pimozide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Kcna10 potassium voltage-gated channel subfamily A member 10 JBrowse link 2 209,920,590 209,932,665 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19764
    role 19711
      application 19361
        pharmaceutical 19230
          drug 19230
            antidyskinesia agent 1133
              pimozide 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19764
    subatomic particle 19762
      composite particle 19762
        hadron 19762
          baryon 19762
            nucleon 19762
              atomic nucleus 19762
                atom 19762
                  main group element atom 19646
                    p-block element atom 19646
                      carbon group element atom 19540
                        carbon atom 19529
                          organic molecular entity 19529
                            organic molecule 19447
                              organic cyclic compound 19207
                                organic heterocyclic compound 18277
                                  organic heteropolycyclic compound 17583
                                    organic heterobicyclic compound 16246
                                      benzimidazoles 827
                                        pimozide 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.