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ONTOLOGY REPORT - ANNOTATIONS


Term:piperacillin
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Accession:CHEBI:8232 term browser browse the term
Definition:A penicillin in which the substituent at position 6 of the penam ring is a 2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido group.
Synonyms:exact_synonym: 6beta-{(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylic acid
 related_synonym: (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   Formula=C23H27N5O7S;   InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1;   InChIKey=IVBHGBMCVLDMKU-GXNBUGAJSA-N;   Piperacillin anhydrous;   SMILES=[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)N1CCN(CC)C(=O)C1=O)c1ccccc1)C(O)=O
 alt_id: CHEBI:472443;   CHEBI:475140;   CHEBI:505944
 xref: Beilstein:6081140 "Beilstein";   CAS:61477-96-1 "ChemIDplus";   CAS:61477-96-1 "KEGG COMPOUND";   DrugBank:DB00319;   Drug_Central:2187 "DrugCentral";   KEGG:C14034;   KEGG:D08380;   LINCS:LSM-5924
 xref_mesh: MESH:D010878
 xref: PMID:1701026 "Europe PMC";   PMID:17116662 "ChEMBL";   PMID:17158942 "ChEMBL";   PMID:17851079 "ChEMBL";   PMID:25998949 "Europe PMC";   PMID:29017833 "Europe PMC";   PMID:29148816 "Europe PMC";   PMID:7486906 "Europe PMC";   Patent:DE2519400;   Patent:US4087424;   Reaxys:6081140 "Reaxys";   Wikipedia:Piperacillin
 cyclic_relationship: is_conjugate_acid_of CHEBI:52433


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piperacillin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il22 interleukin 22 JBrowse link 7 61,236,037 61,240,502 RGD:6480464
G Mir155 microRNA 155 JBrowse link 11 24,176,603 24,176,667 RGD:6480464
G Mir18a microRNA 18a JBrowse link 15 100,180,015 100,180,110 RGD:6480464
G Mir21 microRNA 21 JBrowse link 10 73,902,210 73,902,301 RGD:6480464
G Mr1 major histocompatibility complex, class I-related JBrowse link 13 72,771,992 72,789,861 RGD:6480464
G RT1-DMb RT1 class II, locus DMb JBrowse link 20 3,945,383 3,952,838 RGD:6480464
G Slc25a20 solute carrier family 25 member 20 JBrowse link 8 117,455,308 117,476,762 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        aetiopathogenetic role 18781
          allergen 16858
            penicillin 259
              piperacillin 12
                piperacilloyl group + 0
                piperacilloyl-L-lysine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                lactam 7814
                                                  beta-lactam 784
                                                    beta-lactam antibiotic 772
                                                      penams 259
                                                        penicillanic acids 259
                                                          penicillanic acid 259
                                                            6-aminopenicillanic acid 259
                                                              penicillin 259
                                                                penicillin allergen 256
                                                                  piperacillin 12
                                                                    piperacilloyl group + 0
                                                                    piperacilloyl-L-lysine + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.