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ONTOLOGY REPORT - ANNOTATIONS


Term:orciprenaline
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Accession:CHEBI:82719 term browser browse the term
Definition:A racemate composed of equimolar amounts of (R)- and (S)-orciprenaline. Used (as its sulfate salt) to relax the airway muscles and improve breathing for patients suffering from asthma or bronchitis.
Synonyms:exact_synonym: rac-5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,3-diol
 related_synonym: (RS)-1-(3,5-Dihydroxyphenyl)-2-isopropylaminoethanol;   (RS)-orciprenaline;   3,5-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol;   Formula=C11H17NO3;   Metaproterenol;   orciprenalina;   orciprenalinum;   rac-5-[1-hydroxy-2-(isopropylamino)ethyl]benzene-1,3-diol;   rac-orciprenaline;   racemic orciprenaline
 xref: CAS:586-06-1 "ChemIDplus";   CAS:586-06-1 "KEGG COMPOUND";   DrugBank:DB00816;   HMDB:HMDB0014954;   KEGG:C07144;   KEGG:D08300
 xref_mesh: MESH:D009921
 xref: PMID:20221832 "Europe PMC";   PMID:21282332 "Europe PMC";   PMID:21410309 "Europe PMC";   PMID:23188641 "Europe PMC";   PMID:24085370 "Europe PMC";   PMID:345368 "Europe PMC";   PMID:368899 "Europe PMC";   PMID:4154486 "Europe PMC";   PMID:4671423 "Europe PMC";   PMID:4671739 "Europe PMC";   PMID:4727875 "Europe PMC";   PMID:4767625 "Europe PMC";   PMID:4806747 "Europe PMC";   PMID:5028606 "Europe PMC";   PMID:5049154 "Europe PMC";   PMID:5138661 "Europe PMC";   PMID:5450670 "Europe PMC";   PMID:5505816 "Europe PMC";   PMID:5505819 "Europe PMC";   PMID:5523085 "Europe PMC";   PMID:5537688 "Europe PMC";   PMID:5677872 "Europe PMC";   PMID:5841669 "Europe PMC";   PMID:7215898 "Europe PMC";   Reaxys:2807247 "Reaxys";   Wikipedia:Orciprenaline


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orciprenaline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcat1 branched chain amino acid transaminase 1 JBrowse link 4 179,259,305 179,340,021 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bnip1 BCL2 interacting protein 1 JBrowse link 10 16,677,077 16,689,321 RGD:6480464
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:6480464
G Fabp3 fatty acid binding protein 3 JBrowse link 5 148,528,854 148,535,597 RGD:6480464
G Fhl1 four and a half LIM domains 1 JBrowse link X 159,112,516 159,172,528 RGD:6480464
G Lmcd1 LIM and cysteine-rich domains 1 JBrowse link 4 144,192,989 144,252,554 RGD:6480464
G Rnd1 Rho family GTPase 1 JBrowse link 7 140,349,138 140,356,209 RGD:6480464
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6480464
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:6480464
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        anti-asthmatic agent 9166
          anti-asthmatic drug 8543
            orciprenaline 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    main group molecular entity 19531
                      s-block molecular entity 19314
                        hydrogen molecular entity 19303
                          hydrides 18231
                            inorganic hydride 17095
                              pnictogen hydride 17053
                                nitrogen hydride 16874
                                  azane 16551
                                    ammonia 16548
                                      organic amino compound 16547
                                        secondary amino compound 6362
                                          5-[1-hydroxy-2-(isopropanylamino)ethyl]benzene-1,3-diol 16
                                            (R)-orciprenaline 16
                                              orciprenaline 16
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.