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Accession:CHEBI:82752 term browser browse the term
Definition:A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltransferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease.
Synonyms:exact_synonym: N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide
 related_synonym: Formula=C23H36N2O4;   Genz-99067;   InChI=1S/C23H36N2O4/c1-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20/h10-11,16,19,23,27H,2-9,12-15,17H2,1H3,(H,24,26)/t19-,23-/m1/s1;   InChIKey=FJZZPCZKBUKGGU-AUSIDOKSSA-N;   SMILES=CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)c1ccc2OCCOc2c1
 xref: CAS:491833-29-5 "ChemIDplus";   CAS:491833-29-5 "KEGG DRUG";   Drug_Central:4834 "DrugCentral";   KEGG:D09893
 xref_mesh: MESH:C522917
 xref: PMID:20439622 "Europe PMC";   PMID:20713962 "Europe PMC";   PMID:20864621 "Europe PMC";   PMID:20872320 "Europe PMC";   PMID:22563139 "Europe PMC";   PMID:24816856 "Europe PMC";   PMID:24835462 "Europe PMC";   PMID:25239269 "Europe PMC";   Reaxys:21475293 "Reaxys";   Wikipedia:Eliglustat
 cyclic_relationship: is_conjugate_base_of CHEBI:83355

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eliglustat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gba glucosylceramidase beta JBrowse link 2 188,511,781 188,522,602 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    chemical entity 19726
      atom 19724
        nonmetal atom 19597
          nitrogen atom 18386
            nitrogen molecular entity 18386
              organonitrogen compound 18174
                carboxamide 16801
                  eliglustat 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                eliglustat 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.