Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:calpain inhibitor
go back to main search page
Accession:CHEBI:82824 term browser browse the term
Definition:An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of any calpain.
Synonyms:related_synonym: calpain inhibitors
 xref: PMID:22253611 "Europe PMC";   PMID:22863139 "Europe PMC";   Wikipedia:Calpain


show annotations for term's descendants       view all columns           Sort by:
 
leupeptin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Aqp8 aquaporin 8 JBrowse link 1 193,424,818 193,430,665 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:6480464
G Cdc25c cell division cycle 25C JBrowse link 18 27,528,768 27,550,316 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Klk8 kallikrein related-peptidase 8 JBrowse link 1 99,735,168 99,742,011 RGD:6480464
G Nefl neurofilament light JBrowse link 15 44,799,378 44,803,251 RGD:6480464
G Plin1 perilipin 1 JBrowse link 1 141,458,907 141,470,927 RGD:6480464
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:6480464
Z-Val-Phe-H term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:6480464
G Capn1 calpain 1 JBrowse link 1 221,346,081 221,370,965 RGD:6480464
G Capn2 calpain 2 JBrowse link 13 100,878,649 100,928,811 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Nefl neurofilament light JBrowse link 15 44,799,378 44,803,251 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Sptan1 spectrin, alpha, non-erythrocytic 1 JBrowse link 3 8,534,437 8,599,259 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        inhibitor 18156
          enzyme inhibitor 18079
            EC 3.* (hydrolase) inhibitor 17562
              EC 3.4.* (hydrolases acting on peptide bond) inhibitor 3122
                EC 3.4.22.* (cysteine endopeptidase) inhibitor 462
                  calpain inhibitor 26
                    (Z)-3-(4-iodophenyl)-2-mercaptoacrylic acid 0
                    EC 3.4.22.52 (calpain-1) inhibitor + 11
                    EC 3.4.22.53 (calpain-2) inhibitor + 11
                    EC 3.4.22.54 (calpain-3) inhibitor 0
                    leupeptin 17
                    leupeptin hemisulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        inhibitor 18156
          enzyme inhibitor 18079
            EC 3.* (hydrolase) inhibitor 17562
              EC 3.4.* (hydrolases acting on peptide bond) inhibitor 3122
                protease inhibitor 1958
                  cysteine protease inhibitor 462
                    calpain inhibitor 26
                      (Z)-3-(4-iodophenyl)-2-mercaptoacrylic acid 0
                      EC 3.4.22.52 (calpain-1) inhibitor + 11
                      EC 3.4.22.53 (calpain-2) inhibitor + 11
                      EC 3.4.22.54 (calpain-3) inhibitor 0
                      leupeptin 17
                      leupeptin hemisulfate 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.