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ONTOLOGY REPORT - ANNOTATIONS


Term:sertaconazole
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Accession:CHEBI:82866 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-sertaconazole. A broad spectrum antifungal with added antipruritic and anti-inflammatory activity used (as its nitrate salt) for treatment of various skin infections.
Synonyms:exact_synonym: rac-1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
 related_synonym: (+-)-1-(2,4-Dichloro-beta-((7-chlorobenzo(b)thien-3-yl)methoxy)phenethyl)imidazole;   (RS)-sertaconazole;   1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole;   7-Chloro-3-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy-methyl)benzo(b)thiophene;   Formula=C20H15Cl3N2OS;   rac-sertaconazole;   racemic sertaconazole;   sertaconazol;   sertaconazolum
 xref: CAS:99592-32-2 "ChemIDplus";   CAS:99592-32-2 "KEGG DRUG";   DrugBank:DB01153;   HMDB:HMDB0015284;   KEGG:D06883
 xref_mesh: MESH:C061131
 xref: PMID:19925567 "Europe PMC";   PMID:20349685 "Europe PMC";   PMID:21746955 "Europe PMC";   PMID:21818511 "Europe PMC";   PMID:21968663 "Europe PMC";   PMID:23210976 "Europe PMC";   PMID:23296325 "Europe PMC";   PMID:23372210 "Europe PMC";   PMID:23441833 "Europe PMC";   PMID:23470235 "Europe PMC";   PMID:23546772 "Europe PMC";   PMID:23566144 "Europe PMC";   PMID:23715821 "Europe PMC";   PMID:23829055 "Europe PMC";   PMID:24171300 "Europe PMC";   PMID:24249897 "Europe PMC";   PMID:24249898 "Europe PMC";   PMID:24511475 "Europe PMC";   PMID:24791343 "Europe PMC";   PMID:24845480 "Europe PMC";   PMID:24881281 "Europe PMC";   PMID:24909149 "Europe PMC";   PMID:24953450 "Europe PMC";   Reaxys:5385663 "Reaxys"


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sertaconazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19749
    chemical entity 19747
      chemical substance 11493
        mixture 10811
          racemate 9689
            sertaconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    p-block element atom 19630
                      carbon group element atom 19523
                        carbon atom 19517
                          organic molecular entity 19517
                            organic molecule 19434
                              organic cyclic compound 19203
                                organic heterocyclic compound 18272
                                  heteroarene 15815
                                    monocyclic heteroarene 13133
                                      azole 12262
                                        diazole 8080
                                          imidazoles 7632
                                            imidazole antifungal agent 1236
                                              imidazole antifungal drug 767
                                                arasertaconazole 1
                                                  sertaconazole 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.