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Accession:CHEBI:83168 term browser browse the term
Definition:A member of the class of pyridines that is (pyridin-2-yl)acrylic acid substituted at position 6 by a [(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl group. It is a non-sedating antihistamine used for treatment of hayfever, urticaria, and rhinitis.
Synonyms:exact_synonym: (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid
 related_synonym: (E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic acid;   BW 825C;   BW A825C;   Formula=C22H24N2O2;   InChI=1S/C22H24N2O2/c1-17-7-9-18(10-8-17)20(13-16-24-14-2-3-15-24)21-6-4-5-19(23-21)11-12-22(25)26/h4-13H,2-3,14-16H2,1H3,(H,25,26)/b12-11+,20-13+;   InChIKey=PWACSDKDOHSSQD-IUTFFREVSA-N;   SMILES=Cc1ccc(cc1)C(=C/CN1CCCC1)\\c1cccc(\\C=C\\C(O)=O)n1;   acrivastina;   acrivastinum
 xref: CAS:87848-99-5 "ChemIDplus";   CAS:87848-99-5 "KEGG DRUG";   Drug_Central:82 "DrugCentral";   KEGG:D02760
 xref_mesh: MESH:C043648
 xref: PMID:1355745 "Europe PMC";   PMID:1715267 "Europe PMC";   PMID:18968530 "Europe PMC";   PMID:1970907 "Europe PMC";   PMID:22936420 "Europe PMC";   PMID:23047471 "Europe PMC";   PMID:24813276 "Europe PMC";   PMID:2569998 "Europe PMC";   PMID:2569999 "Europe PMC";   PMID:2570000 "Europe PMC";   PMID:2570001 "Europe PMC";   PMID:2570003 "Europe PMC";   PMID:2574054 "Europe PMC";   PMID:2859204 "Europe PMC";   PMID:2901993 "Europe PMC";   PMID:2906886 "Europe PMC";   PMID:6149965 "Europe PMC";   PMID:7860231 "Europe PMC";   PMID:8630717 "Europe PMC";   Reaxys:6739893 "Reaxys";   Wikipedia:Acrivastine

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acrivastine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        pharmacological role 18798
          antagonist 16190
            histamine antagonist 4551
              H1-receptor antagonist 4083
                acrivastine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    main group molecular entity 19622
                      s-block molecular entity 19388
                        hydrogen molecular entity 19377
                          hydrides 18283
                            inorganic hydride 17204
                              pnictogen hydride 17166
                                nitrogen hydride 17001
                                  azane 16694
                                    ammonia 16691
                                      organic amino compound 16690
                                        tertiary amino compound 8544
                                          N-alkylpyrrolidine 1091
                                            acrivastine 1
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