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ONTOLOGY REPORT - ANNOTATIONS


Term:N-acylsphingoid
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Accession:CHEBI:83273 term browser browse the term
Definition:A ceramide consisting of an undefined sphingoid base linked to an undefined fatty acid via an amide bond.
Synonyms:related_synonym: Formula=C4H7NO3R2;   N-acyl-D-erythro-sphingoid base;   N-acyl-sphingoid base;   N-acylsphingoids;   SMILES=OC[C@H](NC([*])=O)[C@H](O)[*]


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1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CXCL10 C-X-C motif chemokine ligand 10 JBrowse link 4 76,021,118 76,023,497 RGD:6480464
G IL12B interleukin 12B JBrowse link 5 159,314,780 159,330,487 RGD:6480464
N-\{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl\}sphingosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
N-acetylsphingosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G BAD BCL2 associated agonist of cell death JBrowse link 11 64,269,828 64,284,704 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BCL2L1 BCL2 like 1 JBrowse link 20 31,664,452 31,723,963 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CAV1 caveolin 1 JBrowse link 7 116,525,009 116,561,185 RGD:6480464
G CEBPB CCAAT enhancer binding protein beta JBrowse link 20 50,190,583 50,192,690 RGD:6480464
G CFTR CF transmembrane conductance regulator JBrowse link 7 117,480,025 117,668,665 RGD:6480464
G CLK1 CDC like kinase 1 JBrowse link 2 200,853,009 200,864,658 RGD:6480464
G CTSD cathepsin D JBrowse link 11 1,752,755 1,763,927 RGD:6480464
G DAPK1 death associated protein kinase 1 JBrowse link 9 87,497,228 87,708,634 RGD:6480464
G DFFB DNA fragmentation factor subunit beta JBrowse link 1 3,857,267 3,885,429 RGD:6480464
G DNM1L dynamin 1 like JBrowse link 12 32,679,200 32,745,650 RGD:6480464
G EGF epidermal growth factor JBrowse link 4 109,912,883 110,013,766 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 1 94,529,173 94,541,857 RGD:6480464
G FIS1 fission, mitochondrial 1 JBrowse link 7 101,239,472 101,245,081 RGD:6480464
G GSK3A glycogen synthase kinase 3 alpha JBrowse link 19 42,230,186 42,243,330 RGD:6480464
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 119,821,321 120,095,823 RGD:6480464
G GSTA2 glutathione S-transferase alpha 2 JBrowse link 6 52,750,087 52,763,475 RGD:6480464
G GSTA5 glutathione S-transferase alpha 5 JBrowse link 6 52,831,742 52,846,095 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G HNF1A HNF1 homeobox A JBrowse link 12 120,977,683 121,002,512 RGD:6480464
G HRK harakiri, BCL2 interacting protein JBrowse link 12 116,856,144 116,881,441 RGD:6480464
G ID2 inhibitor of DNA binding 2 JBrowse link 2 8,682,056 8,684,461 RGD:6480464
G IL16 interleukin 16 JBrowse link 15 81,196,879 81,314,058 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G KDR kinase insert domain receptor JBrowse link 4 55,078,481 55,125,595 RGD:6480464
G KLF6 Kruppel like factor 6 JBrowse link 10 3,775,996 3,785,281 RGD:6480464
G LGALS3 galectin 3 JBrowse link 14 55,129,252 55,145,430 RGD:6480464
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 6 136,557,046 136,793,098 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MAPK9 mitogen-activated protein kinase 9 JBrowse link 5 180,233,143 180,292,083 RGD:6480464
G MCL1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 1 150,574,551 150,579,738 RGD:6480464
G MDM2 MDM2 proto-oncogene JBrowse link 12 68,808,149 68,850,686 RGD:6480464
G MFN2 mitofusin 2 JBrowse link 1 11,980,181 12,013,515 RGD:6480464
G MIR15B microRNA 15b JBrowse link 3 160,404,588 160,404,685 RGD:6480464
G MIR20A microRNA 20a JBrowse link 13 91,351,065 91,351,135 RGD:6480464
G MIR25 microRNA 25 JBrowse link 7 100,093,560 100,093,643 RGD:6480464
G MIR622 microRNA 622 JBrowse link 13 90,231,182 90,231,277 RGD:6480464
G MIR629 microRNA 629 JBrowse link 15 70,079,372 70,079,468 RGD:6480464
G MIR630 microRNA 630 JBrowse link 15 72,587,217 72,587,313 RGD:6480464
G MIR663A microRNA 663a JBrowse link 20 26,208,186 26,208,278 RGD:6480464
G MIR93 microRNA 93 JBrowse link 7 100,093,768 100,093,847 RGD:6480464
G MIRLET7B microRNA let-7b JBrowse link 22 46,113,686 46,113,768 RGD:6480464
G MIRLET7D microRNA let-7d JBrowse link 9 94,178,834 94,178,920 RGD:6480464
G MIRLET7E microRNA let-7e JBrowse link 19 51,692,786 51,692,864 RGD:6480464
G MIRLET7I microRNA let-7i JBrowse link 12 62,603,686 62,603,769 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NGF nerve growth factor JBrowse link 1 115,285,915 115,338,253 RGD:6480464
G NRP1 neuropilin 1 JBrowse link 10 33,177,491 33,334,905 RGD:6480464
G NRP2 neuropilin 2 JBrowse link 2 205,682,500 205,798,131 RGD:6480464
G ODC1 ornithine decarboxylase 1 JBrowse link 2 10,439,968 10,448,327 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PINK1 PTEN induced kinase 1 JBrowse link 1 20,633,458 20,651,511 RGD:6480464
G PLAT plasminogen activator, tissue type JBrowse link 8 42,174,718 42,207,565 RGD:6480464
G PLCG1 phospholipase C gamma 1 JBrowse link 20 41,137,519 41,177,626 RGD:6480464
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 3 12,583,601 12,664,201 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G RHOB ras homolog family member B JBrowse link 2 20,447,074 20,449,440 RGD:6480464
G SERPINE1 serpin family E member 1 JBrowse link 7 101,127,104 101,139,247 RGD:6480464
G SOD2 superoxide dismutase 2 JBrowse link 6 159,669,069 159,762,281 RGD:6480464
G STS steroid sulfatase JBrowse link X 7,147,290 7,354,641 RGD:6480464
G TFE3 transcription factor binding to IGHM enhancer 3 JBrowse link X 49,028,726 49,043,357 RGD:6480464
G TGIF1 TGFB induced factor homeobox 1 JBrowse link 18 3,412,009 3,459,978 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464
G TXN thioredoxin JBrowse link 9 110,243,810 110,256,507 RGD:6480464
G TXNIP thioredoxin interacting protein JBrowse link 1 145,992,435 145,996,579 RGD:6480464
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:6480464
N-acylsphinganine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP6 caspase 6 JBrowse link 4 109,688,628 109,703,445 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
N-hexadecanoylsphingosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASAH2 N-acylsphingosine amidohydrolase 2 JBrowse link 10 50,184,861 50,251,564 RGD:6480464
G ATF4 activating transcription factor 4 JBrowse link 22 39,514,494 39,522,686 RGD:6480464
G ATF6 activating transcription factor 6 JBrowse link 1 161,766,320 161,964,070 RGD:6480464
G CS citrate synthase JBrowse link 12 56,271,699 56,300,330 RGD:6480464
G DDIT3 DNA damage inducible transcript 3 JBrowse link 12 57,516,588 57,520,517 RGD:6480464
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 9 125,234,853 125,241,343 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 JBrowse link 3 4,493,348 4,847,840 RGD:6480464
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 JBrowse link 12 26,335,352 26,833,197 RGD:6480464
G LIPC lipase C, hepatic type JBrowse link 15 58,410,457 58,569,844 RGD:6480464
G LIPG lipase G, endothelial type JBrowse link 18 49,560,699 49,599,185 RGD:6480464
G MFN2 mitofusin 2 JBrowse link 1 11,980,181 12,013,515 RGD:6480464
G PACS2 phosphofurin acidic cluster sorting protein 2 JBrowse link 14 105,300,718 105,398,147 RGD:6480464
G PC pyruvate carboxylase JBrowse link 11 66,848,420 66,958,418 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G VDAC1 voltage dependent anion channel 1 JBrowse link 5 133,971,871 134,070,987 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23758
    chemical entity 23721
      atom 23707
        nonmetal atom 23357
          carbon atom 23215
            organic molecular entity 23215
              lipid 19559
                sphingolipid 182
                  ceramide 101
                    N-acylsphingoid 85
                      C20 ceramide 0
                      Cer(d29:1) 0
                      Cer(d33:1) + 0
                      Cer(d34:0) + 0
                      Cer(d34:1) + 16
                      Cer(d34:2) + 0
                      Cer(d37:1) + 0
                      Cer(d38:0) 0
                      Cer(d38:1) + 0
                      Cer(d38:2) + 0
                      Cer(d39:2) + 0
                      Cer(d40:1) + 0
                      Cer(d41:1) + 0
                      Cer(d41:2) + 0
                      Cer(d42:1) + 0
                      Cer(d42:2) + 0
                      Cer(d43:1) + 0
                      Cer(d44:0) + 0
                      Cer(d49:0) 0
                      Cer(t38:1) 0
                      Cer(t44:0) 0
                      N-(ultra-long-chain-acyl)-sphingoid base + 0
                      N-(very-long-chain fatty acyl)-sphingoid base + 0
                      N-acylsphingosine + 81
                      N-palmitoyl-sphingoid base + 16
                      N-stearoyl-sphingoid base + 0
                      dihydroceramide + 3
                      phytoceramide + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 23758
    subatomic particle 23707
      composite particle 23707
        hadron 23707
          baryon 23707
            nucleon 23707
              atomic nucleus 23707
                atom 23707
                  main group element atom 23527
                    p-block element atom 23527
                      carbon group element atom 23238
                        carbon atom 23215
                          organic molecular entity 23215
                            organic group 21900
                              organic divalent group 21872
                                organodiyl group 21872
                                  carbonyl group 21843
                                    carbonyl compound 21843
                                      carboxylic acid 20891
                                        carboacyl group 18987
                                          univalent carboacyl group 18987
                                            carbamoyl group 18375
                                              carboxamide 18375
                                                ceramide 101
                                                  N-acylsphingoid 85
                                                    C20 ceramide 0
                                                    Cer(d29:1) 0
                                                    Cer(d33:1) + 0
                                                    Cer(d34:0) + 0
                                                    Cer(d34:1) + 16
                                                    Cer(d34:2) + 0
                                                    Cer(d37:1) + 0
                                                    Cer(d38:0) 0
                                                    Cer(d38:1) + 0
                                                    Cer(d38:2) + 0
                                                    Cer(d39:2) + 0
                                                    Cer(d40:1) + 0
                                                    Cer(d41:1) + 0
                                                    Cer(d41:2) + 0
                                                    Cer(d42:1) + 0
                                                    Cer(d42:2) + 0
                                                    Cer(d43:1) + 0
                                                    Cer(d44:0) + 0
                                                    Cer(d49:0) 0
                                                    Cer(t38:1) 0
                                                    Cer(t44:0) 0
                                                    N-(ultra-long-chain-acyl)-sphingoid base + 0
                                                    N-(very-long-chain fatty acyl)-sphingoid base + 0
                                                    N-acylsphingosine + 81
                                                    N-palmitoyl-sphingoid base + 16
                                                    N-stearoyl-sphingoid base + 0
                                                    dihydroceramide + 3
                                                    phytoceramide + 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.