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Accession:CHEBI:8452 term browser browse the term
Definition:An aminoacridine that is acridine that is substituted by amino groups at positions 3 and 6. A slow-acting bacteriostat that is effective against many Gram-positive bacteria (but ineffective against spores), its salts were formerly used for treatment of burns and infected wounds.
Synonyms:related_synonym: 2,8-Diaminoacridine;   3,6-acridinediamine;   Formula=C13H11N3;   InChI=1S/C13H11N3/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10/h1-7H,14-15H2;   InChIKey=WDVSHHCDHLJJJR-UHFFFAOYSA-N;   Proflavin;   SMILES=Nc1ccc2cc3ccc(N)cc3nc2c1;   acridine-3,6-diamine;   proflavina;   proflavine;   proflavinum
 alt_id: CHEBI:44910;   CHEBI:45272
 xref: Beilstein:166050 "Beilstein";   CAS:92-62-6 "ChemIDplus";   CAS:92-62-6 "NIST Chemistry WebBook";   DrugBank:DB01123;   Drug_Central:2277 "DrugCentral";   KEGG:C11181
 xref_mesh: MESH:D011370
 xref: PDBeChem:PRL;   PMID:11960666 "Europe PMC";   PMID:20178341 "Europe PMC";   PMID:21435875 "Europe PMC";   PMID:2242050 "Europe PMC";   PMID:22555876 "Europe PMC";   PMID:22978751 "Europe PMC";   PMID:6987510 "Europe PMC";   PMID:7009393 "Europe PMC";   PMID:8579793 "Europe PMC";   Reaxys:166050 "Reaxys";   Wikipedia:Proflavine
 cyclic_relationship: is_conjugate_base_of CHEBI:74711

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3,6-diaminoacridine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esrra estrogen related receptor, alpha JBrowse link 1 222,168,729 222,178,842 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19764
    role 19711
      chemical role 19227
        photochemical role 222
          chromophore 53
            3,6-diaminoacridine 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19764
    subatomic particle 19762
      composite particle 19762
        hadron 19762
          baryon 19762
            nucleon 19762
              atomic nucleus 19762
                atom 19762
                  main group element atom 19646
                    p-block element atom 19646
                      carbon group element atom 19540
                        carbon atom 19529
                          organic molecular entity 19529
                            organic molecule 19447
                              organic cyclic compound 19207
                                organic heterocyclic compound 18277
                                  organic heteropolycyclic compound 17583
                                    organic heterotricyclic compound 13736
                                      dibenzopyridine 150
                                        acridines 112
                                          aminoacridines 17
                                            3,6-diaminoacridine 10
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.