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ONTOLOGY REPORT - ANNOTATIONS


Term:2,5-hexanedione
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Accession:CHEBI:85014 term browser browse the term
Definition:A diketone that is hexane substituted by oxo groups at positions 2 and 5. It is a toxic metabolite of hexane and of 2-hexanone
Synonyms:related_synonym: 1,2-Diacetylethane;   2,5-Diketohexane;   2,5-Hexadione;   Acetonyl acetone;   CH3COCH2CH2COCH3;   Formula=C6H10O2;   InChI=1S/C6H10O2/c1-5(7)3-4-6(2)8/h3-4H2,1-2H3;   InChIKey=OJVAMHKKJGICOG-UHFFFAOYSA-N;   NSC 7621;   SMILES=CC(=O)CCC(C)=O;   acetonylacetone;   alpha,beta-diacetylethane;   hexane-2,5-dione
 xref: CAS:110-13-4
 xref_mesh: MESH:C011269
 xref: MetaCyc:CPD-15521;   PMID:1781736;   PMID:24634916;   PMID:25549948;   Reaxys:506525;   Wikipedia:Hexane-2\,5-dione


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2,5-hexanedione term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abi2 abl-interactor 2 JBrowse link 9 67,234,612 67,284,504 RGD:6480464
G Aco2 aconitase 2 JBrowse link 7 123,102,493 123,145,608 RGD:6480464
G Alox15b arachidonate 15-lipoxygenase, type B JBrowse link 10 55,773,748 55,783,489 RGD:6480464
G Angptl4 angiopoietin-like 4 JBrowse link 7 18,627,814 18,634,043 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l14 BCL2 like 14 JBrowse link 4 168,139,964 168,183,726 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Bfar bifunctional apoptosis regulator JBrowse link 10
10
1,464,658
1,464,783
1,471,152
1,497,653
RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Ccdc171 coiled-coil domain containing 171 JBrowse link 5 101,639,355 102,017,300 RGD:6480464
G Ccdc191 coiled-coil domain containing 191 JBrowse link 11 61,678,138 61,748,773 RGD:6480464
G Cep112 centrosomal protein 112 JBrowse link 10 96,660,294 97,146,426 RGD:6480464
G Cfap221 cilia and flagella associated protein 221 JBrowse link 13 35,952,808 36,024,371 RGD:6480464
G Ckmt1 creatine kinase, mitochondrial 1 JBrowse link 3 113,318,559 113,324,459 RGD:6480464
G Clca2 chloride channel accessory 2 JBrowse link 2 250,954,423 250,981,544 RGD:6480464
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:6480464
G Ctxn1 cortexin 1 JBrowse link 12 2,534,212 2,535,823 RGD:6480464
G Dcn decorin JBrowse link 7 38,742,250 38,782,282 RGD:6480464
G Dennd1a DENN domain containing 1A JBrowse link 3 22,061,120 22,501,502 RGD:6480464
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 JBrowse link 2 257,394,692 257,425,344 RGD:6480464
G Dpp7 dipeptidylpeptidase 7 JBrowse link 3 2,569,135 2,573,387 RGD:6480464
G Dpysl2 dihydropyrimidinase-like 2 JBrowse link 15 43,475,640 43,581,725 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6480464
G Erc1 ELKS/RAB6-interacting/CAST family member 1 JBrowse link 4 152,087,393 152,380,023 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Fasn fatty acid synthase JBrowse link 10 109,987,735 110,005,901 RGD:6480464
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6480464
G Gas2 growth arrest-specific 2 JBrowse link 1 107,234,389 107,363,624 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:6480464
G Glud1 glutamate dehydrogenase 1 JBrowse link 16 10,661,486 10,695,557 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Gsn gelsolin JBrowse link 3 14,456,106 14,508,922 RGD:6480464
G Gstm3l glutathione S-transferase mu 3-like JBrowse link 2 210,761,729 210,766,501 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hdgfl1 HDGF like 1 JBrowse link 17 40,170,522 40,172,518 RGD:6480464
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:6480464
G Ier3 immediate early response 3 JBrowse link 20 3,438,798 3,440,002 RGD:6480464
G Ift81 intraflagellar transport 81 JBrowse link 12 39,420,161 39,507,412 RGD:6480464
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Ina internexin neuronal intermediate filament protein, alpha JBrowse link 1 266,782,835 266,794,389 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:6480464
G Kif6 kinesin family member 6 JBrowse link 9 13,016,973 13,311,971 RGD:6480464
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:6480464
G Loxl1 lysyl oxidase-like 1 JBrowse link 8 63,067,757 63,092,124 RGD:6480464
G Lrrc6 leucine rich repeat containing 6 JBrowse link 7 107,130,402 107,231,507 RGD:6480464
G Lrrc69 leucine rich repeat containing 69 JBrowse link 5 28,133,066 28,321,877 RGD:6480464
G Lyz2 lysozyme 2 JBrowse link 7 60,335,968 60,341,264 RGD:6480464
G Macrod1 mono-ADP ribosylhydrolase 1 JBrowse link 1 222,310,916 222,451,485 RGD:6480464
G Map1a microtubule-associated protein 1A JBrowse link 3 113,251,918 113,272,193 RGD:6480464
G Map1b microtubule-associated protein 1B JBrowse link 2 29,675,391 29,768,750 RGD:6480464
G Map2 microtubule-associated protein 2 JBrowse link 9 73,204,753 73,462,965 RGD:6480464
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:6480464
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:6480464
G Mdh1 malate dehydrogenase 1 JBrowse link 14 106,378,349 106,393,642 RGD:6480464
G Mfap3l microfibril associated protein 3 like JBrowse link 16 32,734,059 32,777,091 RGD:6480464
G Mir10b microRNA 10b JBrowse link 3 61,647,978 61,648,086 RGD:6480464
G Mir1224 microRNA 1224 JBrowse link 11 83,992,628 83,992,712 RGD:6480464
G Mir125a microRNA 125a JBrowse link 1 59,704,827 59,704,911 RGD:6480464
G Mir130b microRNA 130b JBrowse link 11 88,129,773 88,129,854 RGD:6480464
G Mir134 microRNA 134 JBrowse link 6 133,884,547 133,884,619 RGD:6480464
G Mir155 microRNA 155 JBrowse link 11 24,176,603 24,176,667 RGD:6480464
G Mir183 microRNA 183 JBrowse link 4 57,463,569 57,463,678 RGD:6480464
G Mir193 microRNA 193 JBrowse link 10 67,065,896 67,065,981 RGD:6480464
G Mir193a microRNA 193a JBrowse link 10 67,065,885 67,065,996 RGD:6480464
G Mir194-2 microRNA 194-2 JBrowse link 1 221,634,786 221,634,870 RGD:6480464
G Mir196a microRNA 196a JBrowse link 7 144,584,235 144,584,344 RGD:6480464
G Mir196c microRNA 196c JBrowse link 10 84,113,578 84,113,657 RGD:6480464
G Mir199a2 microRNA 199a-2 JBrowse link 13 80,125,487 80,125,596 RGD:6480464
G Mir200c microRNA 200c JBrowse link 4 157,236,786 157,236,854 RGD:6480464
G Mir202 microRNA 202 JBrowse link 1 212,295,630 212,295,701 RGD:6480464
G Mir206 microRNA 206 JBrowse link 9 26,791,764 26,791,847 RGD:6480464
G Mir208a microRNA 208a JBrowse link 15 33,613,451 33,613,533 RGD:6480464
G Mir20a microRNA 20a JBrowse link 15 100,180,334 100,180,418 RGD:6480464
G Mir21 microRNA 21 JBrowse link 10 73,902,210 73,902,301 RGD:6480464
G Mir212 microRNA 212 JBrowse link 10 62,014,702 62,014,812 RGD:6480464
G Mir22 microRNA 22 JBrowse link 10 62,299,592 62,299,686 RGD:6480464
G Mir223 microRNA 223 JBrowse link X 65,367,812 65,367,921 RGD:6480464
G Mir224 microRNA 224 JBrowse link X 152,223,754 152,223,835 RGD:6480464
G Mir27a microRNA 27a JBrowse link 19 25,318,736 25,318,822 RGD:6480464
G Mir27b microRNA 27b JBrowse link 17 823,461 823,557 RGD:6480464
G Mir300 microRNA 300 JBrowse link 6 133,874,152 133,874,230 RGD:6480464
G Mir30a microRNA 30a JBrowse link 9 29,542,635 29,542,705 RGD:6480464
G Mir32 microRNA 32 JBrowse link 5 73,934,255 73,934,324 RGD:6480464
G Mir320a microRNA 320a JBrowse link 15 52,134,276 52,134,357 RGD:6480464
G Mir323 microRNA 323 JBrowse link 6 133,861,199 133,861,284 RGD:6480464
G Mir326 microRNA 326 JBrowse link 1 164,518,401 164,518,495 RGD:6480464
G Mir33 microRNA 33 JBrowse link 7 123,431,612 123,431,680 RGD:6480464
G Mir330 microRNA 330 JBrowse link 1 80,092,681 80,092,777 RGD:6480464
G Mir331 microRNA 331 JBrowse link 7 34,881,095 34,881,190 RGD:6480464
G Mir339 microRNA 339 JBrowse link 12 17,369,002 17,369,097 RGD:6480464
G Mir344-1 microRNA 344-1 RGD:6480464
G Mir345 microRNA 345 JBrowse link 6 132,748,968 132,749,063 RGD:6480464
G Mir3556a microRNA 3556a JBrowse link 4 58,343,919 58,344,036 RGD:6480464
G Mir3558 microRNA 3558 JBrowse link 6 10,992,691 10,992,804 RGD:6480464
G Mir3560 microRNA 3560 JBrowse link X 16,117,863 16,117,974 RGD:6480464
G Mir3573 microRNA 3573 JBrowse link X 68,892,972 68,893,043 RGD:6480464
G Mir3580 microRNA 3580 JBrowse link X 151,295,615 151,295,695 RGD:6480464
G Mir3593 microRNA 3593 JBrowse link 6 76,661,799 76,661,889 RGD:6480464
G Mir370 microRNA 370 JBrowse link 6 133,739,916 133,739,994 RGD:6480464
G Mir375 microRNA 375 JBrowse link 9 82,161,716 82,161,790 RGD:6480464
G Mir412 microRNA 412 JBrowse link 6 133,893,571 133,893,640 RGD:6480464
G Mir423 microRNA 423 JBrowse link 10 63,098,366 63,098,444 RGD:6480464
G Mir433 microRNA 433 JBrowse link 6 133,712,334 133,712,426 RGD:6480464
G Mir450a1 microRNA 450a-1 JBrowse link X 158,153,377 158,153,467 RGD:6480464
G Mir487b microRNA 487b JBrowse link 6 133,877,124 133,877,205 RGD:6480464
G Mir488 microRNA 488 JBrowse link 13 76,198,593 76,198,671 RGD:6480464
G Mir497 microRNA 497 JBrowse link 10 56,844,977 56,845,045 RGD:6480464
G Mir503 microRNA 503 JBrowse link X 158,148,476 158,148,546 RGD:6480464
G Mir541 microRNA 541 JBrowse link 6 133,892,655 133,892,744 RGD:6480464
G Mir542 microRNA 542 JBrowse link X 158,152,146 158,152,224 RGD:6480464
G Mir551b microRNA 551b JBrowse link 2 116,867,647 116,867,744 RGD:6480464
G Mir582 microRNA 582 JBrowse link 2 40,863,750 40,863,830 RGD:6480464
G Mir652 microRNA 652 JBrowse link X 114,002,534 114,002,614 RGD:6480464
G Mir653 microRNA 653 JBrowse link 4 28,658,882 28,658,978 RGD:6480464
G Mir665 microRNA 665 JBrowse link 6 133,706,457 133,706,550 RGD:6480464
G Mir675 microRNA 675 JBrowse link 1 215,745,981 215,746,064 RGD:6480464
G Mir743a microRNA 743a JBrowse link X 151,252,828 151,252,903 RGD:6480464
G Mir760 microRNA 760 JBrowse link 2 225,873,354 225,873,433 RGD:6480464
G Mir770 microRNA 770 JBrowse link 6 133,682,965 133,683,040 RGD:6480464
G Mir7a2 microRNA 7a-2 JBrowse link 1 140,576,396 140,576,490 RGD:6480464
G Mir873 microRNA 873 JBrowse link 5 52,481,076 52,481,152 RGD:6480464
G Mir877 microRNA 877 JBrowse link 20 3,318,872 3,318,956 RGD:6480464
G Mir883 microRNA 883 JBrowse link X 151,260,703 151,260,779 RGD:6480464
G Mirlet7b microRNA let-7b JBrowse link 7 126,590,627 126,590,711 RGD:6480464
G Mirlet7i microRNA let-7i JBrowse link 7 66,802,731 66,802,815 RGD:6480464
G Mtm1 myotubularin 1 JBrowse link 6 18,821,821 18,840,449 RGD:6480464
G Napa NSF attachment protein alpha JBrowse link 1 77,994,227 78,012,846 RGD:6480464
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 JBrowse link 9 99,617,051 99,651,827 RGD:6480464
G Nefh neurofilament heavy JBrowse link 14 85,181,572 85,191,557 RGD:6480464
G Nefl neurofilament light JBrowse link 15 44,799,378 44,803,251 RGD:6480464
G Nefm neurofilament medium JBrowse link 15 44,855,307 44,860,604 RGD:6480464
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase JBrowse link 10 91,879,608 91,986,242 RGD:6480464
G Nupr2 nuclear protein 2, transcriptional regulator JBrowse link 12 30,300,936 30,304,041 RGD:6480464
G Pdia3 protein disulfide isomerase family A, member 3 JBrowse link 3 113,376,983 113,400,707 RGD:6480464
G Pdlim3 PDZ and LIM domain 3 JBrowse link 16 49,543,140 49,574,362 RGD:6480464
G Pgam1 phosphoglycerate mutase 1 JBrowse link 1 261,158,204 261,165,814 RGD:6480464
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 JBrowse link 10 83,635,557 83,643,862 RGD:6480464
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 20 8,165,423 8,169,557 RGD:6480464
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:6480464
G Pou2f1 POU class 2 homeobox 1 JBrowse link 13 84,075,316 84,217,368 RGD:6480464
G Prkcsh protein kinase C substrate 80K-H JBrowse link 8 23,014,802 23,026,507 RGD:6480464
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:6480464
G Pygb glycogen phosphorylase B JBrowse link 3 146,581,063 146,629,504 RGD:6480464
G Pygm glycogen phosphorylase, muscle associated JBrowse link 1 221,756,325 221,771,142 RGD:6480464
G Ralgapa2 Ral GTPase activating protein catalytic subunit alpha 2 JBrowse link 3 140,451,850 140,728,305 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G RGD1304694 similar to CG9646-PA JBrowse link 7 125,853,573 125,893,168 RGD:6480464
G RGD1562608 similar to KIAA1328 protein JBrowse link 18 17,394,586 17,678,605 RGD:6480464
G Rtkn2 rhotekin 2 JBrowse link 20 21,919,486 22,004,279 RGD:6480464
G S100z S100 calcium binding protein Z JBrowse link 2 25,188,381 25,203,627 RGD:6480464
G Sclt1 sodium channel and clathrin linker 1 JBrowse link 2 128,523,376 128,675,668 RGD:6480464
G Septin8 septin 8 JBrowse link 10 38,877,422 38,906,480 RGD:6480464
G Sh2d4a SH2 domain containing 4A JBrowse link 16 23,084,247 23,156,825 RGD:6480464
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:6480464
G Sil1 SIL1 nucleotide exchange factor JBrowse link 18 28,067,476 28,302,008 RGD:6480464
G Slc10a7 solute carrier family 10, member 7 JBrowse link 19 32,857,984 33,081,359 RGD:6480464
G Sltm SAFB-like, transcription modulator JBrowse link 8 76,977,698 77,022,847 RGD:6480464
G Sod3 superoxide dismutase 3 JBrowse link 14 60,958,583 60,971,143 RGD:6480464
G Sppl3 signal peptide peptidase like 3 JBrowse link 12 47,276,485 47,360,552 RGD:6480464
G Sptan1 spectrin, alpha, non-erythrocytic 1 JBrowse link 3 8,534,437 8,599,259 RGD:6480464
G Stmn1 stathmin 1 JBrowse link 5 152,680,412 152,686,807 RGD:6480464
G Strbp spermatid perinuclear RNA binding protein JBrowse link 3 21,817,680 21,956,988 RGD:6480464
G Styxl1 serine/threonine/tyrosine interacting-like 1 JBrowse link 12 23,954,563 23,987,155 RGD:6480464
G Tax1bp1 Tax1 binding protein 1 JBrowse link 4 82,776,720 82,832,586 RGD:6480464
G Tbc1d5 TBC1 domain family, member 5 JBrowse link 9 1,144,641 1,747,732 RGD:6480464
G Tmem192 transmembrane protein 192 JBrowse link 16 26,620,525 26,642,537 RGD:6480464
G Tpi1 triosephosphate isomerase 1 JBrowse link 4 157,328,375 157,331,905 RGD:6480464
G Uba1 ubiquitin-like modifier activating enzyme 1 JBrowse link X 1,723,135 1,745,147 RGD:6480464
G Ubn2 ubinuclein 2 JBrowse link 4 66,164,639 66,254,297 RGD:6480464
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 JBrowse link 1 190,555,177 190,585,741 RGD:6480464
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:6480464
G Zfp169 zinc finger protein 169 JBrowse link 17 16,443,324 16,471,329 RGD:6480464
G Zfp407 zinc finger protein 407 JBrowse link 18 81,057,507 81,453,682 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      biological role 19716
        aetiopathogenetic role 18812
          neurotoxin 17403
            2,5-hexanedione 179
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            organic group 18451
                              organic divalent group 18445
                                organodiyl group 18445
                                  carbonyl group 18346
                                    carbonyl compound 18346
                                      ketone 15978
                                        diketone 1148
                                          2,5-hexanedione 179
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.