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ONTOLOGY REPORT - ANNOTATIONS


Term:potassium clavulanate
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Accession:CHEBI:85264 term browser browse the term
Definition:A potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes and has only weak anitbiotic activity when administered alone. However it can be used in combination with amoxicillin trihydrate (under the trade name Augmentin) for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases.
Synonyms:exact_synonym: potassium (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
 related_synonym: CVA;   Formula=C8H8KNO5;   InChI=1S/C8H9NO5.K/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h1,6-7,10H,2-3H2,(H,12,13);/q;+1/p-1/b4-1-;/t6-,7-;/m1./s1;   InChIKey=ABVRVIZBZKUTMK-JSYANWSFSA-M;   SMILES=[K+].OC\\C=C1/O[C@@H]2CC(=O)N2[C@H]1C([O-])=O
 xref: CAS:61177-45-5 "ChemIDplus";   CAS:61177-45-5 "KEGG DRUG";   DrugBank:DB00766;   KEGG:D02370;   Reaxys:4773605 "Reaxys";   Wikipedia:Clavulanic_Acid


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Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          potassium clavulanate 0
            Augmentin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic ion 7895
                              organic anion 2230
                                carboxylic acid anion 1830
                                  monocarboxylic acid anion 1484
                                    clavulanate 0
                                      potassium clavulanate 0
                                        Augmentin 0
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