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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Human Antigen R Protein Expression Modulator and AkT Inhibitor
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Accession:CHEBI:85516 term browser browse the term
Definition:5'-ATGGACCAAAGAGTTTCAGGGA-3' SsDNA MW 6832 Cell Permeable, Water Soluble, Commercially Available. Human Antigen R regulates proliferation, survival, localized angiogenesis, metastasis, and resistance to programmed cell death. HuR protein expression has been shown to affect the clinical-efficacy of common cancer drugs. In PC3 cells the oglionucleotide reduced cell growth inhibited both cell migration an AkT Serine 473 phosphorylation.
Synonyms:related_synonym: ELAVL1


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  CHEBI ontology 19810
    role 19758
      biological role 19758
        Human Antigen R Protein Expression Modulator and AkT Inhibitor 0
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