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ONTOLOGY REPORT - ANNOTATIONS


Term:4beta-hydroxycholesterol
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Accession:CHEBI:85778 term browser browse the term
Definition:A oxysterol that is cholesterol in which the hydrogen at the 4beta position has been replaced by a hydroxy group. A metabolite of cholesterol formed by the drug-metabolizing enzyme cytochrome P450 3A4, it is one of the major oxysterols in the human circulation.
Synonyms:exact_synonym: cholest-5-ene-3beta,4beta-diol
 related_synonym: (3beta,4beta)-cholest-5-ene-3,4-diol;   Formula=C27H46O2;   InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)20-11-12-21-19-9-10-23-25(29)24(28)14-16-27(23,5)22(19)13-15-26(20,21)4/h10,17-22,24-25,28-29H,6-9,11-16H2,1-5H3/t18-,19+,20-,21+,22+,24+,25-,26-,27-/m1/s1;   InChIKey=CZDKQKOAHAICSF-JSAMMMMSSA-N;   SMILES=CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4[C@@H](O)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C;   cholest-5-en-3beta,4beta-diol
 xref: CAS:17320-10-4 "ChemIDplus";   HMDB:HMDB0013643;   LIPID_MAPS_instance:LMST01010014 "LIPID MAPS"
 xref_mesh: MESH:C099828
 xref: PMID:11514559 "Europe PMC";   PMID:12077124 "SUBMITTER";   PMID:18279471 "Europe PMC";   PMID:18300941 "Europe PMC";   PMID:19006545 "Europe PMC";   PMID:19458613 "Europe PMC";   PMID:21728364 "Europe PMC";   PMID:8656065 "SUBMITTER"


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Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          metabolite 19151
            eukaryotic metabolite 18770
              algal metabolite 13312
                cholesterol 312
                  4beta-hydroxycholesterol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic polycyclic compound 16027
                                  steroid 12770
                                    hydroxy steroid 12362
                                      3-hydroxy steroid 9989
                                        3beta-hydroxy steroid 1979
                                          3beta-hydroxy-Delta(5)-steroid 1838
                                            cholesterol 312
                                              oxysterol 91
                                                4beta-hydroxycholesterol 0
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