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ONTOLOGY REPORT - ANNOTATIONS


Term:conazole antifungal agent
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Accession:CHEBI:86323 term browser browse the term
Definition:A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function.
Synonyms:related_synonym: azole antibiotic;   azole antibiotics;   conazole antifungal agents
 alt_id: CHEBI:60593


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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23810
    role 23697
      biological role 23660
        antimicrobial agent 20127
          antifungal agent 16644
            conazole antifungal agent 2909
              conazole antifungal drug + 787
              conazole fungicide + 2426
              diniconazole-M + 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 23810
    subatomic particle 23761
      composite particle 23761
        hadron 23761
          baryon 23761
            nucleon 23761
              atomic nucleus 23761
                atom 23761
                  main group element atom 23578
                    p-block element atom 23578
                      carbon group element atom 23292
                        carbon atom 23245
                          organic molecular entity 23245
                            organic molecule 23109
                              organic cyclic compound 22095
                                organic heterocyclic compound 20732
                                  heteroarene 17130
                                    monocyclic heteroarene 14198
                                      azole 13437
                                        conazole antifungal agent 2909
                                          conazole antifungal drug + 787
                                          conazole fungicide + 2426
                                          diniconazole-M + 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.