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ONTOLOGY REPORT - ANNOTATIONS


Term:conazole antifungal agent
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Accession:CHEBI:86323 term browser browse the term
Definition:A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function.
Synonyms:related_synonym: azole antibiotic;   azole antibiotics;   conazole antifungal agents
 alt_id: CHEBI:60593


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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21269
    role 21253
      biological role 21251
        antimicrobial agent 18131
          antifungal agent 14981
            conazole antifungal agent 2933
              conazole antifungal drug + 792
              conazole fungicide + 2446
              diniconazole-M + 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 21269
    subatomic particle 21265
      composite particle 21265
        hadron 21265
          baryon 21265
            nucleon 21265
              atomic nucleus 21265
                atom 21265
                  main group element atom 21134
                    p-block element atom 21134
                      carbon group element atom 20905
                        carbon atom 20795
                          organic molecular entity 20795
                            organic molecule 20677
                              organic cyclic compound 20134
                                organic heterocyclic compound 18995
                                  heteroarene 15974
                                    monocyclic heteroarene 13307
                                      azole 12547
                                        conazole antifungal agent 2933
                                          conazole antifungal drug + 792
                                          conazole fungicide + 2446
                                          diniconazole-M + 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.