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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(S)-fluoxetine hydrochloride
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Accession:CHEBI:86997 term browser browse the term
Definition:A hydrochloride obtained by reaction of (S)-fluoxetine with one equivalent of hydrochloric acid.
Synonyms:exact_synonym: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride
 related_synonym: (+)-fluoxetine hydrochloride;   (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium chloride;   (S)-fluoxetine HCl;   Formula=C17H19ClF3NO;   InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m0./s1;   InChIKey=GIYXAJPCNFJEHY-NTISSMGPSA-N;   SMILES=Cl.CNCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1
 xref: CAS:114247-06-2
 cyclic_relationship: is_enantiomer_of CHEBI:86996


show annotations for term's descendants           Sort by:
 
fluoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP fluoxetine decreases expression of Slc6a4 mRNA in the dorsal raphe nucleus RGD PMID:15936043 RGD:38549581 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        pharmacological role 18793
          neurotransmitter agent 16423
            serotonergic drug 3956
              serotonin uptake inhibitor 3321
                (S)-fluoxetine hydrochloride 1
                  fluoxetine hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      halogen 18012
                        chlorine atom 17793
                          chlorine molecular entity 17793
                            elemental chlorine 8372
                              monoatomic chlorine 8353
                                chloride 8353
                                  chloride salt 8353
                                    organic chloride salt 664
                                      hydrochloride 435
                                        (S)-fluoxetine hydrochloride 1
                                          fluoxetine hydrochloride 1
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