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Accession:CHEBI:87681 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-ranolazine. Used for treatment of chronic angina.
Synonyms:exact_synonym: rac-N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide
 related_synonym: (+-)-N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide;   (RS)-ranolazine;   Formula=C24H33N3O4;   Ranexa;   rac-ranolazine;   racemic ranolazine
 xref: CAS:95635-55-5 "ChemIDplus";   CAS:95635-55-5 "KEGG DRUG";   DrugBank:DB00243;   KEGG:D05700
 xref_mesh: MESH:D000069458
 xref: PMID:25041234 "Europe PMC";   PMID:25188881 "Europe PMC";   PMID:25210025 "Europe PMC";   PMID:25346368 "Europe PMC";   PMID:25346483 "Europe PMC";   PMID:25416563 "Europe PMC";   PMID:25496982 "Europe PMC";   PMID:25515836 "Europe PMC";   PMID:25544118 "Europe PMC";   PMID:25555283 "Europe PMC";   PMID:25602175 "Europe PMC";   PMID:25738014 "Europe PMC";   PMID:25761430 "Europe PMC";   PMID:25828315 "Europe PMC";   PMID:25848292 "Europe PMC";   PMID:25872749 "Europe PMC";   PMID:26021246 "Europe PMC";   PMID:26049552 "Europe PMC";   PMID:26049922 "Europe PMC";   PMID:26059896 "Europe PMC";   PMID:26138210 "Europe PMC";   PMID:26183665 "Europe PMC";   PMID:26185330 "Europe PMC";   PMID:26226999 "Europe PMC";   PMID:26245658 "Europe PMC";   Patent:EP126449;   Patent:US4567264;   Reaxys:8234797 "Reaxys";   Wikipedia:Ranolazine

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ranolazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    chemical entity 19739
      chemical substance 11479
        mixture 10797
          racemate 9676
            ranolazine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        carboacyl group 17073
                                          univalent carboacyl group 17073
                                            carbamoyl group 16800
                                              carboxamide 16800
                                                monocarboxylic acid amide 14162
                                                  N-(2,6-dimethylphenyl)-2-\{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl\}acetamide 3
                                                    (S)-ranolazine 3
                                                      ranolazine 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.