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Accession:CHEBI:87681 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-ranolazine. Used for treatment of chronic angina.
Synonyms:exact_synonym: rac-N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide
 related_synonym: (+-)-N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide;   (RS)-ranolazine;   Formula=C24H33N3O4;   Ranexa;   rac-ranolazine;   racemic ranolazine
 xref: CAS:95635-55-5 "ChemIDplus";   CAS:95635-55-5 "KEGG DRUG";   DrugBank:DB00243;   KEGG:D05700
 xref_mesh: MESH:D000069458
 xref: PMID:25041234 "Europe PMC";   PMID:25188881 "Europe PMC";   PMID:25210025 "Europe PMC";   PMID:25346368 "Europe PMC";   PMID:25346483 "Europe PMC";   PMID:25416563 "Europe PMC";   PMID:25496982 "Europe PMC";   PMID:25515836 "Europe PMC";   PMID:25544118 "Europe PMC";   PMID:25555283 "Europe PMC";   PMID:25602175 "Europe PMC";   PMID:25738014 "Europe PMC";   PMID:25761430 "Europe PMC";   PMID:25828315 "Europe PMC";   PMID:25848292 "Europe PMC";   PMID:25872749 "Europe PMC";   PMID:26021246 "Europe PMC";   PMID:26049552 "Europe PMC";   PMID:26049922 "Europe PMC";   PMID:26059896 "Europe PMC";   PMID:26138210 "Europe PMC";   PMID:26183665 "Europe PMC";   PMID:26185330 "Europe PMC";   PMID:26226999 "Europe PMC";   PMID:26245658 "Europe PMC";   Patent:EP126449;   Patent:US4567264;   Reaxys:8234797 "Reaxys";   Wikipedia:Ranolazine

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ranolazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 26 8,148,181 8,209,392 RGD:6480464
G EGR1 early growth response 1 JBrowse link 11 26,046,195 26,049,806 RGD:6480464
G GATA4 GATA binding protein 4 JBrowse link 25 26,126,172 26,211,474 RGD:6480464
G NAB1 NGFI-A binding protein 1 JBrowse link 37 1,207,619 1,243,546 RGD:6480464
G SLC8A1 solute carrier family 8 member A1 JBrowse link 17 32,004,207 32,381,399 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 223
    chemical entity 223
      chemical substance 26
        mixture 26
          racemate 12
            ranolazine 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 223
    subatomic particle 223
      composite particle 223
        hadron 223
          baryon 223
            nucleon 223
              atomic nucleus 223
                atom 223
                  main group element atom 216
                    p-block element atom 216
                      carbon group element atom 205
                        carbon atom 204
                          organic molecular entity 204
                            organic group 153
                              organic divalent group 152
                                organodiyl group 152
                                  carbonyl group 152
                                    carbonyl compound 152
                                      carboxylic acid 112
                                        carboacyl group 47
                                          univalent carboacyl group 47
                                            carbamoyl group 44
                                              carboxamide 44
                                                monocarboxylic acid amide 19
                                                  N-(2,6-dimethylphenyl)-2-\{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl\}acetamide 5
                                                    (S)-ranolazine 5
                                                      ranolazine 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.