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ONTOLOGY REPORT - ANNOTATIONS


Term:ranolazine
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Accession:CHEBI:87681 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-ranolazine. Used for treatment of chronic angina.
Synonyms:exact_synonym: rac-N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide
 related_synonym: (+-)-N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide;   (RS)-ranolazine;   Formula=C24H33N3O4;   Ranexa;   rac-ranolazine;   racemic ranolazine
 xref: CAS:95635-55-5 "ChemIDplus";   CAS:95635-55-5 "KEGG DRUG";   DrugBank:DB00243;   KEGG:D05700
 xref_mesh: MESH:D000069458
 xref: PMID:25041234 "Europe PMC";   PMID:25188881 "Europe PMC";   PMID:25210025 "Europe PMC";   PMID:25346368 "Europe PMC";   PMID:25346483 "Europe PMC";   PMID:25416563 "Europe PMC";   PMID:25496982 "Europe PMC";   PMID:25515836 "Europe PMC";   PMID:25544118 "Europe PMC";   PMID:25555283 "Europe PMC";   PMID:25602175 "Europe PMC";   PMID:25738014 "Europe PMC";   PMID:25761430 "Europe PMC";   PMID:25828315 "Europe PMC";   PMID:25848292 "Europe PMC";   PMID:25872749 "Europe PMC";   PMID:26021246 "Europe PMC";   PMID:26049552 "Europe PMC";   PMID:26049922 "Europe PMC";   PMID:26059896 "Europe PMC";   PMID:26138210 "Europe PMC";   PMID:26183665 "Europe PMC";   PMID:26185330 "Europe PMC";   PMID:26226999 "Europe PMC";   PMID:26245658 "Europe PMC";   Patent:EP126449;   Patent:US4567264;   Reaxys:8234797 "Reaxys";   Wikipedia:Ranolazine


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ranolazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    chemical entity 19746
      chemical substance 11490
        mixture 10810
          racemate 9688
            ranolazine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic group 18426
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18306
                                    carbonyl compound 18306
                                      carboxylic acid 17973
                                        carboacyl group 17082
                                          univalent carboacyl group 17082
                                            carbamoyl group 16811
                                              carboxamide 16811
                                                monocarboxylic acid amide 14170
                                                  N-(2,6-dimethylphenyl)-2-\{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl\}acetamide 3
                                                    (S)-ranolazine 3
                                                      ranolazine 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.