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ONTOLOGY REPORT - ANNOTATIONS


Term:azaribine
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Accession:CHEBI:88272 term browser browse the term
Definition:A N-glycosyl-1,2,4-triazine that is 6-azauridine acetylated at positions 2', 3' and 5' on the sugar ring. It is a prodrug for 6-azauridine and is used for treatment of psoriasis.
Synonyms:exact_synonym: 2-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
 related_synonym: 2',3',5'-Tri-O-acetyl-6-azauridine;   2',3',5'-Triacetyl-6-azauridine;   2-(2',3',5'-Triacetyl-beta-D-ribofuranosyl)-as-triazine-3,5-(2H,4H)-dione;   2-beta-D-Ribofuranosyl-as-triazine-3,5(2H,4H)-dione 2',3',5'-triacetate;   6-Azauridine 2',3',5'-triacetate;   Formula=C14H17N3O9;   InChI=1S/C14H17N3O9/c1-6(18)23-5-9-11(24-7(2)19)12(25-8(3)20)13(26-9)17-14(22)16-10(21)4-15-17/h4,9,11-13H,5H2,1-3H3,(H,16,21,22)/t9-,11-,12-,13-/m1/s1;   InChIKey=QQOBRRFOVWGIMD-OJAKKHQRSA-N;   SMILES=N=1N(C(NC(C1)=O)=O)[C@@H]2O[C@@H]([C@H]([C@H]2OC(=O)C)OC(C)=O)COC(C)=O;   Triacetyl-6-azauridine;   Triazure;   azaribina;   azaribinum
 xref: Beilstein:631776;   CAS:2169-64-4;   Drug_Central:27;   KEGG:D03029;   LINCS:LSM-20874
 xref_mesh: MESH:C100231
 xref: PMID:1036874;   PMID:1096923;   PMID:11600283;   PMID:1173747;   PMID:1243822;   PMID:14023746;   PMID:203231;   PMID:324277;   PMID:5137963;   PMID:5171778;   PMID:5911950;   PMID:6198500;   PMID:766762;   PMID:8570536;   Reaxys:631776


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azaribine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Umps uridine monophosphate synthetase JBrowse link 11 70,034,181 70,044,590 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      application 19366
        pro-agent 8833
          prodrug 8623
            azaribine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            heteroorganic entity 19121
                              organochalcogen compound 18824
                                organooxygen compound 18738
                                  carbohydrates and carbohydrate derivatives 12127
                                    carbohydrate 12127
                                      carbohydrate derivative 11752
                                        glycosyl compound 10808
                                          N-glycosyl compound 5327
                                            N-glycosyl-1,2,4-triazine 1
                                              6-azauridine 1
                                                azaribine 1
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