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ONTOLOGY REPORT - ANNOTATIONS


Term:pyrrolotriazine
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Accession:CHEBI:88341 term browser browse the term
Definition:Any organic heterobicyclic compound containing ortho-fused pyrrolidine and triazine rings.
Synonyms:related_synonym: pyrrolotriazines


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BMS-754807 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:6480464
G Cdk6 cyclin-dependent kinase 6 JBrowse link 4 27,781,728 27,969,653 RGD:6480464
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:6480464
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    chemical entity 19769
      atom 19768
        nonmetal atom 19641
          nitrogen atom 18449
            nitrogen molecular entity 18449
              organonitrogen compound 18249
                organonitrogen heterocyclic compound 17217
                  pyrrolotriazine 8
                    4-\{[5-(methoxycarbamoyl)-2-methylphenyl]amino\}-5-methyl-N-[(1S)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 0
                    BMS-754807 8
                    GS-441524 + 0
                    N-(3-AMINOPROPYL)-N-[(R)-(3-BENZYL-5-CHLORO-4-OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL)(CYCLOPROPYL)METHYL]-4-METHYLBENZAMIDE 0
                    N-ethyl-4-\{[5-(methoxycarbamoyl)-2-methylphenyl]amino\}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 0
                    remdesivir 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19653
                    p-block element atom 19653
                      p-block molecular entity 19653
                        carbon group molecular entity 19548
                          organic molecular entity 19537
                            organic molecule 19456
                              organic cyclic compound 19213
                                organic heterocyclic compound 18293
                                  organic heteropolycyclic compound 17588
                                    organic heterobicyclic compound 16253
                                      pyrrolotriazine 8
                                        4-\{[5-(methoxycarbamoyl)-2-methylphenyl]amino\}-5-methyl-N-[(1S)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 0
                                        BMS-754807 8
                                        GS-441524 + 0
                                        N-(3-AMINOPROPYL)-N-[(R)-(3-BENZYL-5-CHLORO-4-OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL)(CYCLOPROPYL)METHYL]-4-METHYLBENZAMIDE 0
                                        N-ethyl-4-\{[5-(methoxycarbamoyl)-2-methylphenyl]amino\}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 0
                                        remdesivir 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.