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Term:cotinine N-oxide
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Accession:CHEBI:89087 term browser browse the term
Definition:An N-alkylpyrrolidine that is nicotine in which the methylene hydrogens at position 2 on the pyrrolidine ring have been replaced by an oxo group and the pyridine nitrogen converted to the corresponding N-oxide. A minor metabolite of nicotine.
Synonyms:exact_synonym: (5S)-1-methyl-5-(1-oxo-1lambda(5)-pyridin-3-yl)pyrrolidin-2-one
 related_synonym: (5S)-1-methyl-5-(1-oxido-3-pyridinyl)-2-pyrrolidinone;   (S)-1-methyl-5-(1-oxido-3-pyridinyl)-2-Pyrrolidinone;   (S)-1-methyl-5-(3-pyridinyl)-2-Pyrrolidinone N-oxide;   3-[(2S)-1-methyl-5-oxopyrrolidin-2-yl]pyridin-1-ium-1-olate;   Formula=C10H12N2O2;   InChI=1S/C10H12N2O2/c1-11-9(4-5-10(11)13)8-3-2-6-12(14)7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1;   InChIKey=CIPULDKLIIVIER-VIFPVBQESA-N;   SMILES=CN1[C@@](CCC1=O)(C2=C[N+](=CC=C2)[O-])[H]
 xref: CAS:36508-80-2 "ChemIDplus";   HMDB:HMDB0001411;   MetaCyc:CPD-3185;   PMID:1478978 "Europe PMC";   PMID:15109883 "Europe PMC";   PMID:1521032 "Europe PMC";   PMID:15472033 "Europe PMC";   PMID:16359169 "Europe PMC";   PMID:17640086 "Europe PMC";   PMID:19065315 "Europe PMC";   PMID:19466395 "Europe PMC";   PMID:20097626 "Europe PMC";   PMID:20301889 "Europe PMC";   PMID:20822672 "Europe PMC";   PMID:20980010 "Europe PMC";   PMID:21452992 "Europe PMC";   PMID:21719221 "Europe PMC";   PMID:23022114 "Europe PMC";   PMID:23318728 "Europe PMC";   PMID:23737496 "Europe PMC";   PMID:23983622 "Europe PMC";   PMID:24755743 "Europe PMC";   PMID:24968308 "Europe PMC";   PMID:25013964 "Europe PMC";   PMID:25304849 "Europe PMC";   PMID:26721601 "Europe PMC";   PMID:27480511 "Europe PMC";   PMID:3443673 "Europe PMC";   PMID:4625531 "Europe PMC";   PMID:8294547 "Europe PMC";   Reaxys:6479802 "Reaxys"

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      biological role 19693
        immunomodulator 13677
          nicotine 1045
            cotinine N-oxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic group 18426
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18306
                                    carbonyl compound 18306
                                      carboxylic acid 17973
                                        carboacyl group 17082
                                          univalent carboacyl group 17082
                                            carbamoyl group 16811
                                              carboxamide 16811
                                                lactam 7820
                                                  gamma-lactam 6059
                                                    pyrrolidin-2-ones 131
                                                      cotinine N-oxide 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.