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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dibromoacetic acid
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Accession:CHEBI:90124 term browser browse the term
Definition:A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are replaced by bromo groups.
Synonyms:related_synonym: 2,2-Dibromoacetic acid;   2,2-dibromoethanoic acid;   DBAA;   Dibromoethanoic acid;   Formula=C2H2Br2O2;   InChI=1S/C2H2Br2O2/c3-1(4)2(5)6/h1H,(H,5,6);   InChIKey=SIEILFNCEFEENQ-UHFFFAOYSA-N;   SMILES=C(Br)(Br)C(=O)O
 xref: CAS:631-64-1;   KEGG:C20123;   LIPID_MAPS_instance:LMFA01090076
 xref_mesh: MESH:C088674
 xref: PMID:23348848;   PMID:25556763;   PMID:25955755;   PMID:26052022;   PMID:26188195;   Reaxys:1700457


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dibromoacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 increases expression ISO dibromoacetic acid results in increased expression of ATF2 mRNA CTD PMID:29155130 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO dibromoacetic acid results in decreased expression of BCL2 mRNA CTD PMID:18628252 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases expression ISO dibromoacetic acid results in increased expression of CASP3 protein modified form CTD PMID:29155130 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ces3a carboxylesterase 3a decreases expression EXP dibromoacetic acid results in decreased expression of CES3 mRNA CTD PMID:21046364 NCBI chr19:37,070,705...37,079,411 JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP dibromoacetic acid results in decreased expression of COL1A2 mRNA CTD PMID:21046364 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP17A1 mRNA CTD PMID:21046364 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP1B1 mRNA CTD PMID:21046364 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Dpt dermatopontin decreases expression EXP dibromoacetic acid results in decreased expression of DPT mRNA CTD PMID:21046364 NCBI chr13:83,073,307...83,102,404
Ensembl chr13:83,073,544...83,102,401
JBrowse link
G Elk1 ETS transcription factor ELK1 increases expression ISO dibromoacetic acid results in increased expression of ELK1 mRNA CTD PMID:29155130 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP dibromoacetic acid inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:10580743 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP dibromoacetic acid results in decreased expression of FADS1 mRNA CTD PMID:21046364 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO dibromoacetic acid results in increased expression of FAS mRNA; dibromoacetic acid results in increased expression of FAS protein CTD PMID:18628252 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression ISO dibromoacetic acid results in increased expression of FASL protein CTD PMID:18628252 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP dibromoacetic acid results in decreased expression of HAO2 mRNA CTD PMID:21046364 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP dibromoacetic acid results in decreased expression of HBA-A2 mRNA CTD PMID:21046364 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP dibromoacetic acid results in decreased expression of HBB mRNA CTD PMID:21046364 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression EXP dibromoacetic acid results in decreased expression of IGFBP7 mRNA CTD PMID:21046364 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Insl3 insulin-like 3 decreases expression EXP dibromoacetic acid results in decreased expression of INSL3 mRNA CTD PMID:21046364 NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases methylation ISO dibromoacetic acid results in decreased methylation of MYC promoter CTD PMID:16014735 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Traf2 Tnf receptor-associated factor 2 increases expression ISO dibromoacetic acid results in increased expression of TRAF2 mRNA CTD PMID:18628252 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        biochemical role 19313
          apoptosis inducer 10979
            dibromoacetic acid 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        monocarboxylic acid 17476
                                          acetic acid 10814
                                            dibromoacetic acid 20
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