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Accession:CHEBI:90232 term browser browse the term
Definition:A nucleoside analogue that is adenine in which the nitrogen at position 9 has been substituted by a tetrahydrofuran-2-yl group. It is an adenylate cyclase inhibitor.
Synonyms:exact_synonym: 9-(tetrahydrofuran-2-yl)-9H-purin-6-amine
 related_synonym: 6-amino-9-(tetrahydro-2-furyl)-9H-purine;   9-(tetrahydro-2-furanyl)-9H-purin-6-amine;   9-(tetrahydro-2-furyl)-adenine;   Formula=C9H11N5O;   InChI=1S/C9H11N5O/c10-8-7-9(12-4-11-8)14(5-13-7)6-2-1-3-15-6/h4-6H,1-3H2,(H2,10,11,12);   InChIKey=UKHMZCMKHPHFOT-UHFFFAOYSA-N;   SMILES=C12=C(N=CN1C3OCCC3)C(=NC=N2)N;   SQ 22,536;   SQ-22536;   SQ22536
 xref: CAS:17318-31-9 "ChemIDplus";   LINCS:LSM-1656
 xref_mesh: MESH:C017759
 xref: PMID:10193763 "Europe PMC";   PMID:11334872 "Europe PMC";   PMID:11858802 "Europe PMC";   PMID:1669444 "Europe PMC";   PMID:1711430 "Europe PMC";   PMID:26350463 "SUBMITTER";   PMID:6326343 "Europe PMC";   Reaxys:534250 "Reaxys"

show annotations for term's descendants       view all columns           Sort by:
9-(tetrahydrofuryl)adenine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:6480464
G Pnpla6 patatin-like phospholipase domain containing 6 JBrowse link 12 2,068,749 2,098,139 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        inhibitor 18143
          enzyme inhibitor 18066
            EC 4.* (lyase) inhibitor 3657
              EC 4.6.* (P-O lyase) inhibitor 69
                EC (adenylate cyclase) inhibitor 5
                  9-(tetrahydrofuryl)adenine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  organic heteropolycyclic compound 17500
                                    organic heterobicyclic compound 15910
                                      imidazopyrimidine 5415
                                        purines 5413
                                          aminopurine 4372
                                            6-aminopurines 757
                                              adenine 751
                                                9-(tetrahydrofuryl)adenine 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.