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Accession:CHEBI:90232 term browser browse the term
Definition:A nucleoside analogue that is adenine in which the nitrogen at position 9 has been substituted by a tetrahydrofuran-2-yl group. It is an adenylate cyclase inhibitor.
Synonyms:exact_synonym: 9-(tetrahydrofuran-2-yl)-9H-purin-6-amine
 related_synonym: 6-amino-9-(tetrahydro-2-furyl)-9H-purine;   9-(tetrahydro-2-furanyl)-9H-purin-6-amine;   9-(tetrahydro-2-furyl)-adenine;   Formula=C9H11N5O;   InChI=1S/C9H11N5O/c10-8-7-9(12-4-11-8)14(5-13-7)6-2-1-3-15-6/h4-6H,1-3H2,(H2,10,11,12);   InChIKey=UKHMZCMKHPHFOT-UHFFFAOYSA-N;   SMILES=C12=C(N=CN1C3OCCC3)C(=NC=N2)N;   SQ 22,536;   SQ-22536;   SQ22536
 xref: CAS:17318-31-9 "ChemIDplus";   LINCS:LSM-1656
 xref_mesh: MESH:C017759
 xref: PMID:10193763 "Europe PMC";   PMID:11334872 "Europe PMC";   PMID:11858802 "Europe PMC";   PMID:1669444 "Europe PMC";   PMID:1711430 "Europe PMC";   PMID:26350463 "SUBMITTER";   PMID:6326343 "Europe PMC";   Reaxys:534250 "Reaxys"

show annotations for term's descendants       view all columns           Sort by:
9-(tetrahydrofuryl)adenine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:6480464
G Pnpla6 patatin-like phospholipase domain containing 6 JBrowse link 12 2,068,749 2,098,139 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        inhibitor 18163
          enzyme inhibitor 18085
            EC 4.* (lyase) inhibitor 3658
              EC 4.6.* (P-O lyase) inhibitor 69
                EC (adenylate cyclase) inhibitor 5
                  9-(tetrahydrofuryl)adenine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic molecule 19431
                              organic cyclic compound 19197
                                organic heterocyclic compound 18267
                                  organic heteropolycyclic compound 17574
                                    organic heterobicyclic compound 16239
                                      imidazopyrimidine 5415
                                        purines 5413
                                          aminopurine 4370
                                            6-aminopurines 761
                                              adenine 755
                                                9-(tetrahydrofuryl)adenine 3
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.