Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:1-(3-\{5-[4-(aminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl\}phenyl)-3-(2-phenoxyphenyl)urea
go back to main search page
Accession:CHEBI:90541 term browser browse the term
Definition:A member of the class of phenylureas obtained by formal condensation of the carboxy group of (3-{5-[4-(aminomethyl)phenyl]pyrrolo[2,3-b]pyridin-3-yl}phenyl)carbamic acid with the amino group of 2-phenoxyaniline. An inhibitor of tyrosine kinase.
Synonyms:related_synonym: Formula=C33H27N5O2;   InChI=1S/C33H27N5O2/c34-19-22-13-15-23(16-14-22)25-18-28-29(21-36-32(28)35-20-25)24-7-6-8-26(17-24)37-33(39)38-30-11-4-5-12-31(30)40-27-9-2-1-3-10-27/h1-18,20-21H,19,34H2,(H,35,36)(H2,37,38,39);   InChIKey=KSTUYVHCHCYOAB-UHFFFAOYSA-N;   SMILES=C(C1=CC=C(C=C1)C2=CN=C3NC=C(C4=CC=CC(NC(=O)NC5=CC=CC=C5OC6=CC=CC=C6)=C4)C3=C2)N
 xref: PDBeChem:351;   PMID:19394223;   PMID:22571659;   Reaxys:19791836


show annotations for term's descendants       view all columns           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      application 19363
        refrigerant 17249
          ammonia 16703
            organic amino compound 16702
              primary amino compound 7836
                1-(3-\{5-[4-(aminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl\}phenyl)-3-(2-phenoxyphenyl)urea 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            organic group 18451
                              organic divalent group 18445
                                organodiyl group 18445
                                  carbonyl group 18346
                                    carbonyl compound 18346
                                      carboxylic acid 18019
                                        carboacyl group 17177
                                          univalent carboacyl group 17177
                                            carbamoyl group 16916
                                              carboxamide 16916
                                                monocarboxylic acid amide 14567
                                                  urea 4983
                                                    ureas 4980
                                                      phenylureas 1978
                                                        1-(3-\{5-[4-(aminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl\}phenyl)-3-(2-phenoxyphenyl)urea 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.