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Accession:CHEBI:90693 term browser browse the term
Definition:An aryl sulfide that is (2Z,3Z)-bis[amino(sulfanyl)methylidene]butanedinitrile in which the sulfanyl hydrogens are replaced by 2-aminophenyl groups. An inhibitor of mitogen-activated protein kinase that also exhibits anti-cancer properties.
Synonyms:exact_synonym: (2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylene}succinonitrile
 related_synonym: FT-1069-1;   Formula=C18H16N6S2;   InChI=1S/C18H16N6S2/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22/h1-8H,21-24H2/b17-11+,18-12+;   InChIKey=DVEXZJFMOKTQEZ-JYFOCSDGSA-N;   SMILES=C=1(C=CC=CC1N)S/C(=C(/C(/C#N)=C(/SC=2C(=CC=CC2)N)\\N)\\C#N)/N;   U 0126
 alt_id: CHEBI:64208
 xref: CAS:109511-58-2;   CAS:218601-62-8;   LINCS:LSM-42806;   PDBeChem:5BM;   PMID:21618303;   PMID:22025280;   PMID:22052387;   PMID:22075021;   PMID:22101421;   PMID:22129618;   PMID:22182511;   PMID:22273495;   PMID:22286127;   PMID:22301382;   PMID:22313325;   PMID:22354777;   PMID:22396328;   PMID:24947959;   PMID:25363751;   PMID:25407271;   PMID:25492115;   PMID:25544156;   PMID:26349244;   PMID:9660836;   Reaxys:3483750;   Wikipedia:U0126

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U0126 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:15090804

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      chemical role 19224
        antioxidant 14151
          U0126 1
            U0126.EtOH 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    main group molecular entity 19641
                      s-block molecular entity 19403
                        hydrogen molecular entity 19392
                          hydrides 18362
                            inorganic hydride 17222
                              pnictogen hydride 17186
                                nitrogen hydride 17020
                                  azane 16711
                                    ammonia 16709
                                      organic amino compound 16708
                                        aromatic amine 13619
                                          anilines 12327
                                            substituted aniline 11824
                                              U0126 1
                                                U0126.EtOH 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.