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Accession:CHEBI:90933 term browser browse the term
Definition:An N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichlorophenyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder.
Synonyms:exact_synonym: N'-(trans-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl)-N,N-dimethylurea
 related_synonym: Formula=C21H32Cl2N4O;   InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-;   InChIKey=KPWSJANDNDDRMB-QAQDUYKDSA-N;   RGH 188;   SMILES=C1[C@H](CC[C@@H](C1)CCN2CCN(CC2)C=3C(=C(C=CC3)Cl)Cl)NC(N(C)C)=O
 xref: CAS:839712-12-8 "ChemIDplus";   CAS:839712-12-8 "KEGG DRUG";   DrugBank:DB06016;   Drug_Central:5037 "DrugCentral";   KEGG:D09997
 xref_mesh: MESH:C533287
 xref: PMID:22537450 "Europe PMC";   PMID:23138433 "Europe PMC";   PMID:23966785 "Europe PMC";   PMID:24048386 "Europe PMC";   PMID:24229617 "Europe PMC";   PMID:24412468 "Europe PMC";   PMID:24975932 "Europe PMC";   PMID:25056368 "Europe PMC";   PMID:25083572 "Europe PMC";   PMID:25532076 "Europe PMC";   PMID:25562205 "Europe PMC";   PMID:25692006 "Europe PMC";   PMID:26044980 "Europe PMC";   PMID:26075487 "Europe PMC";   PMID:26160196 "Europe PMC";   PMID:26419293 "Europe PMC";   PMID:26472602 "Europe PMC";   PMID:26510944 "Europe PMC";   PMID:26541814 "Europe PMC";   PMID:26586950 "Europe PMC";   PMID:26655189 "Europe PMC";   PMID:26655732 "Europe PMC";   PMID:26717533 "Europe PMC";   PMID:26723167 "Europe PMC";   Reaxys:18784658 "Reaxys";   Wikipedia:Cariprazine
 cyclic_relationship: is_conjugate_base_of CHEBI:90934

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cariprazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        agrochemical 13449
          fertilizer 9536
            urea 4949
              ureas 4946
                cariprazine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                monocarboxylic acid amide 14163
                                                  urea 4949
                                                    ureas 4946
                                                      cariprazine 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.