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ONTOLOGY REPORT - ANNOTATIONS


Term:Senkirkine
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Accession:CHEBI:9111 term browser browse the term
Definition:A macrolide that has formula C19H27NO6.
Synonyms:related_synonym: Formula=C19H27NO6;   InChI=1S/C19H27NO6/c1-5-13-10-12(2)19(3,24)18(23)25-11-14-6-8-20(4)9-7-15(16(14)21)26-17(13)22/h5-6,12,15,24H,7-11H2,1-4H3/b13-5-,14-6-/t12-,15-,19-/m1/s1;   InChIKey=HPDHKHMHQGCNPE-QLJRNOHWSA-N;   SMILES=C\\C=C1\\C[C@@H](C)[C@@](C)(O)C(=O)OC\\C2=C\\CN(C)CC[C@@H](OC1=O)C2=O
 xref: CAS:2318-18-5 "KEGG COMPOUND";   KEGG:C10396;   KNApSAcK:C00002119
 xref_mesh: MESH:C009238


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Senkirkine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Abcc6 ATP binding cassette subfamily C member 6 JBrowse link 1 101,954,786 102,013,252 RGD:6480464
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:6480464
G Acsm3 acyl-CoA synthetase medium-chain family member 3 JBrowse link 1 189,514,504 189,541,233 RGD:6480464
G Aff3 AF4/FMR2 family, member 3 JBrowse link 9 44,837,979 45,291,964 RGD:6480464
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase JBrowse link 9 100,281,339 100,291,292 RGD:6480464
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 JBrowse link 17 42,133,076 42,159,413 RGD:6480464
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 JBrowse link 6 108,146,552 108,167,185 RGD:6480464
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 JBrowse link 1 16,910,043 16,929,465 RGD:6480464
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Ces3a carboxylesterase 3a JBrowse link 19 37,070,705 37,079,411 RGD:6480464
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 JBrowse link 5 134,492,734 134,507,158 RGD:6480464
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 JBrowse link 7 15,179,472 15,191,113 RGD:6480464
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 JBrowse link 16 19,501,680 19,528,935 RGD:6480464
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:6480464
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 JBrowse link 8 130,548,418 130,550,388 RGD:6480464
G Dhrs9 dehydrogenase/reductase 9 JBrowse link 3 55,623,671 55,645,883 RGD:6480464
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 2 221,823,692 222,694,627 RGD:6480464
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Fmo3 flavin containing dimethylaniline monoxygenase 3 JBrowse link 13 80,837,418 80,856,214 RGD:6480464
G Fmo4 flavin containing dimethylaniline monoxygenase 4 JBrowse link 13 80,685,385 80,703,575 RGD:6480464
G Fmo5 flavin containing dimethylaniline monoxygenase 5 JBrowse link 2 199,796,870 199,823,927 RGD:6480464
G Gamt guanidinoacetate N-methyltransferase JBrowse link 7 12,314,848 12,317,998 RGD:6480464
G Gem GTP binding protein overexpressed in skeletal muscle JBrowse link 5 25,339,479 25,353,661 RGD:6480464
G Gls glutaminase JBrowse link 9 54,212,622 54,284,879 RGD:6480464
G Glyat glycine-N-acyltransferase JBrowse link 1 229,060,125 229,081,113 RGD:6480464
G Gphn gephyrin JBrowse link 6 101,327,874 101,859,169 RGD:6480464
G Gprc5a G protein-coupled receptor, class C, group 5, member A JBrowse link 4 168,832,937 168,851,650 RGD:6480464
G Hnmt histamine N-methyltransferase JBrowse link 3 905,111 937,038 RGD:6480464
G Isg20 interferon stimulated exonuclease gene 20 JBrowse link 1 140,602,553 140,608,892 RGD:6480464
G Maff MAF bZIP transcription factor F JBrowse link 7 120,580,743 120,592,095 RGD:6480464
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:6480464
G Maob monoamine oxidase B JBrowse link X 6,430,694 6,533,520 RGD:6480464
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:6480464
G Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit JBrowse link 3 140,106,723 140,125,047 RGD:6480464
G Neb nebulin JBrowse link 3 37,658,081 37,855,843 RGD:6480464
G Nnmt nicotinamide N-methyltransferase JBrowse link 8 52,918,437 52,938,172 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Ptprd protein tyrosine phosphatase, receptor type, D JBrowse link 5 92,862,229 93,514,071 RGD:6480464
G Rapgef4 Rap guanine nucleotide exchange factor 4 JBrowse link 3 58,632,338 58,925,127 RGD:6480464
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator JBrowse link 19 561,696 564,929 RGD:6480464
G Slc10a1 solute carrier family 10 member 1 JBrowse link 6 104,617,730 104,631,355 RGD:6480464
G Slc22a25 solute carrier family 22, member 25 JBrowse link 1 224,596,886 224,698,512 RGD:6480464
G Slc22a7 solute carrier family 22 member 7 JBrowse link 9 16,925,321 16,931,119 RGD:6480464
G Slco2b1 solute carrier organic anion transporter family, member 2b1 JBrowse link 1 164,623,313 164,671,612 RGD:6480464
G Sult1e1 sulfotransferase family 1E member 1 JBrowse link 14 22,070,861 22,089,264 RGD:6480464
G Sult2a1 sulfotransferase family 2A member 1 JBrowse link 1 76,558,721 76,614,315 RGD:6480464
G Tenm1 teneurin transmembrane protein 1 JBrowse link X
X
129,034,755
128,923,951
129,336,023
128,951,520
RGD:6480464
G Tenm2 teneurin transmembrane protein 2 JBrowse link 10 20,846,091 21,791,771 RGD:6480464
G Uchl3 ubiquitin C-terminal hydrolase L3 JBrowse link 15 86,153,624 86,198,127 RGD:6480464
G Ugt3a2 UDP glycosyltransferase 3 family, polypeptide A2 JBrowse link 2 58,666,337 58,682,212 RGD:6480464
G Vps13b vacuolar protein sorting 13 homolog B JBrowse link 7 74,118,834 74,722,341 RGD:6480464
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    chemical entity 19739
      atom 19737
        nonmetal atom 19610
          oxygen atom 19295
            oxygen molecular entity 19295
              organooxygen compound 18704
                polyketide 8501
                  macrolide 1457
                    Senkirkine 64
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic ester 13967
                                        lactone 5864
                                          macrocyclic lactone 1518
                                            macrolide 1457
                                              Senkirkine 64
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.