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ONTOLOGY REPORT - ANNOTATIONS


Term:sirolimus
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Accession:CHEBI:9168 term browser browse the term
Definition:A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent.
Synonyms:exact_synonym: (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
 related_synonym: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone;   Antibiotic AY 22989;   Formula=C51H79NO13;   InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33+,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1;   InChIKey=QFJCIRLUMZQUOT-HPLJOQBZSA-N;   Rapamune;   SMILES=[H][C@]1(CC[C@@H](O)[C@@H](C1)OC)C[C@@H](C)[C@]1([H])CC(=O)[C@H](C)\\C=C(C)\\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\\C=C\\C=C\\C=C(C)\\[C@H](C[C@]2([H])CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@@]2([H])C(=O)O1)OC;   rapamycin;   sirolimusum
 alt_id: CHEBI:45276;   CHEBI:67812
 xref: CAS:53123-88-9 "ChemIDplus";   CAS:53123-88-9 "KEGG COMPOUND";   DrugBank:DB00877;   Drug_Central:2446 "DrugCentral";   HMDB:HMDB0015015;   KEGG:C07909;   KEGG:D00753;   KNApSAcK:C00018055;   LIPID_MAPS_instance:LMPK06000003 "LIPID MAPS"
 xref_mesh: MESH:D020123
 xref: PDBeChem:RAP;   PMID:22960739 "Europe PMC";   PMID:22981852 "Europe PMC";   PMID:22984623 "Europe PMC";   Reaxys:5848501 "Reaxys";   Wikipedia:Rapamycin


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sirolimus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2M alpha-2-macroglobulin JBrowse link 12 9,067,708 9,116,229 RGD:6480464
G ABCA1 ATP binding cassette subfamily A member 1 JBrowse link 9 104,781,006 104,928,232 RGD:6480464
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
G ABCC2 ATP binding cassette subfamily C member 2 JBrowse link 10 99,782,602 99,853,741 RGD:6480464
G ABCC8 ATP binding cassette subfamily C member 8 JBrowse link 11 17,392,498 17,476,849 RGD:6480464
G ACADL acyl-CoA dehydrogenase long chain JBrowse link 2 210,187,923 210,225,447 RGD:6480464
G ACADM acyl-CoA dehydrogenase medium chain JBrowse link 1 75,724,347 75,763,679 RGD:6480464
G ACE2 angiotensin I converting enzyme 2 JBrowse link X 15,494,520 15,602,158 RGD:6480464
G ACER2 alkaline ceramidase 2 JBrowse link 9 19,408,927 19,455,173 RGD:6480464
G ACTA2 actin alpha 2, smooth muscle JBrowse link 10 88,935,074 88,991,397 RGD:6480464
G ACTB actin beta JBrowse link 7 5,527,148 5,530,601 RGD:6480464
G AGT angiotensinogen JBrowse link 1 230,702,523 230,714,122 RGD:6480464
G AIFM1 apoptosis inducing factor mitochondria associated 1 JBrowse link X 130,129,362 130,165,887 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G AKT1S1 AKT1 substrate 1 JBrowse link 19 49,869,033 49,878,356 RGD:6480464
G AKT2 AKT serine/threonine kinase 2 JBrowse link 19 40,230,317 40,285,531 RGD:6480464
G ANGPTL6 angiopoietin like 6 JBrowse link 19 10,092,337 10,106,407 RGD:6480464
G AOPEP aminopeptidase O (putative) JBrowse link 9 94,726,669 95,148,264 RGD:6480464
G APOD apolipoprotein D JBrowse link 3 195,568,705 195,583,940 RGD:6480464
G APP amyloid beta precursor protein JBrowse link 21 25,880,550 26,171,128 RGD:6480464
G AQP2 aquaporin 2 JBrowse link 12 49,950,741 49,958,881 RGD:6480464
G AR androgen receptor JBrowse link X 67,544,021 67,730,619 RGD:6480464
G ASNS asparagine synthetase (glutamine-hydrolyzing) JBrowse link 7 97,851,677 97,928,441 RGD:6480464
G ATF3 activating transcription factor 3 JBrowse link 1 212,565,334 212,620,777 RGD:6480464
G ATF4 activating transcription factor 4 JBrowse link 22 39,514,494 39,522,686 RGD:6480464
G ATG4A autophagy related 4A cysteine peptidase JBrowse link X 108,091,667 108,154,671 RGD:6480464
G ATG4B autophagy related 4B cysteine peptidase JBrowse link 2 241,637,659 241,673,857 RGD:6480464
G ATG5 autophagy related 5 JBrowse link 6 106,184,476 106,325,820 RGD:6480464
G AURKB aurora kinase B JBrowse link 17 8,204,731 8,210,767 RGD:6480464
G BAD BCL2 associated agonist of cell death JBrowse link 11 64,269,828 64,284,704 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BBC3 BCL2 binding component 3 JBrowse link 19 47,220,822 47,232,998 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BCL2L1 BCL2 like 1 JBrowse link 20 31,664,452 31,723,963 RGD:6480464
G BCL2L11 BCL2 like 11 JBrowse link 2 111,120,914 111,168,445 RGD:6480464
G BDNF brain derived neurotrophic factor JBrowse link 11 27,654,893 27,722,030 RGD:6480464
G BECN1 beclin 1 JBrowse link 17 42,810,132 42,824,316 RGD:6480464
G BID BH3 interacting domain death agonist JBrowse link 22 17,734,140 17,774,665 RGD:6480464
G BIRC2 baculoviral IAP repeat containing 2 JBrowse link 11 102,347,182 102,378,670 RGD:6480464
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 17 78,214,253 78,225,635 RGD:6480464
G BNIP3 BCL2 interacting protein 3 JBrowse link 10 131,967,683 131,982,013 RGD:6480464
G BTBD11 BTB domain containing 11 JBrowse link 12 107,316,749 107,659,642 RGD:6480464
G BTC betacellulin JBrowse link 4 74,744,759 74,794,718 RGD:6480464
G BTK Bruton tyrosine kinase JBrowse link X 101,349,447 101,390,796 RGD:6480464
G BUB1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 2 110,637,528 110,678,107 RGD:6480464
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 15 40,161,069 40,221,123 RGD:6480464
G C1QA complement C1q A chain JBrowse link 1 22,636,628 22,639,682 RGD:6480464
G C1QC complement C1q C chain JBrowse link 1 22,643,633 22,648,108 RGD:6480464
G C3 complement C3 JBrowse link 19 6,677,704 6,720,650 RGD:6480464
G CALD1 caldesmon 1 JBrowse link 7 134,779,629 134,970,729 RGD:6480464
G CAMK2A calcium/calmodulin dependent protein kinase II alpha JBrowse link 5 150,219,491 150,290,130 RGD:6480464
G CAPN1 calpain 1 JBrowse link 11 65,181,373 65,212,006 RGD:6480464
G CASP1 caspase 1 JBrowse link 11 105,025,443 105,035,591 RGD:6480464
G CASP12 caspase 12 (gene/pseudogene) JBrowse link 11 104,885,718 104,898,670 RGD:6480464
G CASP2 caspase 2 JBrowse link 7 143,288,351 143,307,696 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP7 caspase 7 JBrowse link 10 113,679,162 113,730,909 RGD:6480464
G CASP8 caspase 8 JBrowse link 2 201,233,443 201,287,711 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CAV3 caveolin 3 JBrowse link 3 8,733,802 8,746,758 RGD:6480464
G CCN2 cellular communication network factor 2 JBrowse link 6 131,948,176 131,951,372 RGD:6480464
G CCNA2 cyclin A2 JBrowse link 4 121,816,444 121,823,883 RGD:6480464
G CCNB2 cyclin B2 JBrowse link 15 59,105,146 59,125,045 RGD:6480464
G CCND1 cyclin D1 JBrowse link 11 69,641,156 69,654,474 RGD:6480464
G CCND2 cyclin D2 JBrowse link 12 4,273,762 4,305,353 RGD:6480464
G CCND3 cyclin D3 JBrowse link 6 41,934,933 42,048,894 RGD:6480464
G CCNE2 cyclin E2 JBrowse link 8 94,880,224 94,896,671 RGD:6480464
G CCNG2 cyclin G2 JBrowse link 4 77,157,207 77,170,060 RGD:6480464
G CCNI cyclin I JBrowse link 4 77,047,155 77,075,989 RGD:6480464
G CD36 CD36 molecule JBrowse link 7 80,602,207 80,679,277 RGD:6480464
G CD38 CD38 molecule JBrowse link 4 15,778,328 15,853,232 RGD:6480464
G CD68 CD68 molecule JBrowse link 17 7,579,638 7,582,111 RGD:6480464
G CD80 CD80 molecule JBrowse link 3 119,524,293 119,559,614 RGD:6480464
G CD84 CD84 molecule JBrowse link 1 160,541,094 160,579,516 RGD:6480464
G CD86 CD86 molecule JBrowse link 3 122,055,362 122,121,143 RGD:6480464
G CDC20 cell division cycle 20 JBrowse link 1 43,358,981 43,363,203 RGD:6480464
G CDH1 cadherin 1 JBrowse link 16 68,737,292 68,835,537 RGD:6480464
G CDH2 cadherin 2 JBrowse link 18 27,932,878 28,177,130 RGD:6480464
G CDK1 cyclin dependent kinase 1 JBrowse link 10 60,778,331 60,794,852 RGD:6480464
G CDK2 cyclin dependent kinase 2 JBrowse link 12 55,966,830 55,972,789 RGD:6480464
G CDK4 cyclin dependent kinase 4 JBrowse link 12 57,747,727 57,752,310 RGD:6480464
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 36,676,463 36,687,332 RGD:6480464
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 12,717,270 12,722,383 RGD:6480464
G CDX2 caudal type homeobox 2 JBrowse link 13 27,960,918 27,969,368 RGD:6480464
G CEBPA CCAAT enhancer binding protein alpha JBrowse link 19 33,299,934 33,302,564 RGD:6480464
G CENPX centromere protein X JBrowse link 17 82,018,703 82,022,930 RGD:6480464
G CFD complement factor D JBrowse link 19 859,664 863,641 RGD:6480464
G CHRNB3 cholinergic receptor nicotinic beta 3 subunit JBrowse link 8 42,697,366 42,737,407 RGD:6480464
G CKS1B CDC28 protein kinase regulatory subunit 1B JBrowse link 1 154,974,642 154,979,251 RGD:6480464
G CLDN7 claudin 7 JBrowse link 17 7,259,903 7,263,193 RGD:6480464
G CLEC4A C-type lectin domain family 4 member A JBrowse link 12 8,102,902 8,138,607 RGD:6480464
G COL1A1 collagen type I alpha 1 chain JBrowse link 17 50,184,096 50,201,649 RGD:6480464
G COL1A2 collagen type I alpha 2 chain JBrowse link 7 94,394,895 94,431,227 RGD:6480464
G CP ceruloplasmin JBrowse link 3 149,162,410 149,222,008 RGD:6480464
G CPT1B carnitine palmitoyltransferase 1B JBrowse link 22 50,568,861 50,578,612 RGD:6480464
G CPT2 carnitine palmitoyltransferase 2 JBrowse link 1 53,196,824 53,214,197 RGD:6480464
G CREB1 cAMP responsive element binding protein 1 JBrowse link 2 207,529,943 207,605,988 RGD:6480464
G CREBRF CREB3 regulatory factor JBrowse link 5 173,056,349 173,139,284 RGD:6480464
G CRTC2 CREB regulated transcription coactivator 2 JBrowse link 1 153,947,675 153,958,643 RGD:6480464
G CSE1L chromosome segregation 1 like JBrowse link 20 49,046,246 49,096,960 RGD:6480464
G CSF1 colony stimulating factor 1 JBrowse link 1 109,910,506 109,930,992 RGD:6480464
G CSF2 colony stimulating factor 2 JBrowse link 5 132,073,789 132,076,170 RGD:6480464
G CTNNB1 catenin beta 1 JBrowse link 3 41,199,422 41,240,445 RGD:6480464
G CTSK cathepsin K JBrowse link 1 150,796,208 150,808,260 RGD:6480464
G CXCL10 C-X-C motif chemokine ligand 10 JBrowse link 4 76,021,118 76,023,497 RGD:6480464
G CXCL13 C-X-C motif chemokine ligand 13 JBrowse link 4 77,511,753 77,611,834 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 73,740,569 73,743,716 RGD:6480464
G CYBA cytochrome b-245 alpha chain JBrowse link 16 88,643,289 88,651,079 RGD:6480464
G CYBB cytochrome b-245 beta chain JBrowse link X 37,780,059 37,813,461 RGD:6480464
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 JBrowse link 2 218,781,733 218,815,293 RGD:6480464
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 JBrowse link 19 40,843,541 40,850,447 RGD:6480464
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 JBrowse link 19 40,991,282 41,018,398 RGD:6480464
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 JBrowse link 10 94,938,658 94,990,091 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G DDIT3 DNA damage inducible transcript 3 JBrowse link 12 57,516,588 57,520,517 RGD:6480464
G DDIT4L DNA damage inducible transcript 4 like JBrowse link 4 100,185,870 100,190,468 RGD:6480464
G DEPTOR DEP domain containing MTOR interacting protein JBrowse link 8 119,873,655 120,050,918 RGD:6480464
G DIABLO diablo IAP-binding mitochondrial protein JBrowse link 12 122,207,662 122,227,456 RGD:6480464
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 1 65,264,694 65,415,871 RGD:6480464
G DNMT1 DNA methyltransferase 1 JBrowse link 19 10,133,346 10,194,953 RGD:6480464
G DPYD dihydropyrimidine dehydrogenase JBrowse link 1 97,077,743 97,921,059 RGD:6480464
G DUSP10 dual specificity phosphatase 10 JBrowse link 1 221,701,420 221,742,176 RGD:6480464
G DUSP15 dual specificity phosphatase 15 JBrowse link 20 31,845,578 31,870,744 RGD:6480464
G E2F1 E2F transcription factor 1 JBrowse link 20 33,675,477 33,686,385 RGD:6480464
G E2F4 E2F transcription factor 4 JBrowse link 16 67,192,155 67,198,918 RGD:6480464
G EDN1 endothelin 1 JBrowse link 6 12,256,463 12,297,194 RGD:6480464
G EEF2 eukaryotic translation elongation factor 2 JBrowse link 19 3,976,056 3,985,463 RGD:6480464
G EGF epidermal growth factor JBrowse link 4 109,912,883 110,013,766 RGD:6480464
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:6480464
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha JBrowse link 14 67,360,328 67,386,516 RGD:6480464
G EIF4B eukaryotic translation initiation factor 4B JBrowse link 12 53,006,456 53,042,215 RGD:6480464
G EIF4E eukaryotic translation initiation factor 4E JBrowse link 4 98,871,684 98,930,637 RGD:6480464
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 8 38,030,534 38,060,365 RGD:6480464
G EIF4G1 eukaryotic translation initiation factor 4 gamma 1 JBrowse link 3 184,314,495 184,335,358 RGD:6480464
G EIF4G2 eukaryotic translation initiation factor 4 gamma 2 JBrowse link 11 10,797,046 10,809,035 RGD:6480464
G ERN1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 17 64,039,142 64,132,469 RGD:6480464
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha JBrowse link 14 52,639,915 52,695,750 RGD:6480464
G ESPL1 extra spindle pole bodies like 1, separase JBrowse link 12 53,268,257 53,293,643 RGD:6480464
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:6480464
G EVI2A ecotropic viral integration site 2A JBrowse link 17 31,316,410 31,321,622 RGD:6480464
G EWSR1 EWS RNA binding protein 1 JBrowse link 22 29,268,254 29,300,523 RGD:6480464
G F2 coagulation factor II, thrombin JBrowse link 11 46,719,201 46,739,506 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 1 94,529,173 94,541,857 RGD:6480464
G FAS Fas cell surface death receptor JBrowse link 10 88,968,429 89,017,059 RGD:6480464
G FASLG Fas ligand JBrowse link 1 172,659,008 172,666,876 RGD:6480464
G FAXDC2 fatty acid hydroxylase domain containing 2 JBrowse link 5 154,817,018 154,850,683 RGD:6480464
G FBLN1 fibulin 1 JBrowse link 22 45,502,883 45,601,135 RGD:6480464
G FBXO32 F-box protein 32 JBrowse link 8 123,497,887 123,541,206 RGD:6480464
G FBXO5 F-box protein 5 JBrowse link 6 152,970,535 152,983,579 RGD:6480464
G FCGR1A Fc fragment of IgG receptor Ia JBrowse link 1 149,782,071 149,792,518 RGD:6480464
G FGB fibrinogen beta chain JBrowse link 4 154,562,980 154,572,763 RGD:6480464
G FGF1 fibroblast growth factor 1 JBrowse link 5 142,592,178 142,698,070 RGD:6480464
G FGF7 fibroblast growth factor 7 JBrowse link 15 49,423,242 49,488,775 RGD:6480464
G FKBP1A FKBP prolyl isomerase 1A JBrowse link 20 1,368,977 1,393,172 RGD:6480464
G FLT3LG fms related receptor tyrosine kinase 3 ligand JBrowse link 19 49,474,172 49,487,037 RGD:6480464
G FOLR1 folate receptor alpha JBrowse link 11 72,189,709 72,196,323 RGD:6480464
G FOXM1 forkhead box M1 JBrowse link 12 2,857,680 2,877,174 RGD:6480464
G FOXO1 forkhead box O1 JBrowse link 13 40,555,667 40,666,641 RGD:6480464
G FOXO3 forkhead box O3 JBrowse link 6 108,559,825 108,684,774 RGD:6480464
G FOXP1 forkhead box P1 JBrowse link 3 70,952,817 71,583,989 RGD:6480464
G FOXP3 forkhead box P3 JBrowse link X 49,250,436 49,264,932 RGD:6480464
G FRAT1 FRAT regulator of WNT signaling pathway 1 JBrowse link 10 97,319,271 97,321,915 RGD:6480464
G FSHB follicle stimulating hormone subunit beta JBrowse link 11 30,231,014 30,235,277 RGD:6480464
G FTL ferritin light chain JBrowse link 19 48,963,941 48,966,879 RGD:6480464
G GABARAP GABA type A receptor-associated protein JBrowse link 17 7,240,008 7,242,449 RGD:6480464
G GABARAPL1 GABA type A receptor associated protein like 1 JBrowse link 12 10,212,877 10,223,128 RGD:6480464
G GCM2 glial cells missing transcription factor 2 JBrowse link 6 10,873,223 10,882,041 RGD:6480464
G GEM GTP binding protein overexpressed in skeletal muscle JBrowse link 8 94,249,249 94,262,345 RGD:6480464
G GGT1 gamma-glutamyltransferase 1 JBrowse link 22 24,583,750 24,629,005 RGD:6480464
G GLB1 galactosidase beta 1 JBrowse link 3 32,996,608 33,097,230 RGD:6480464
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 7 1,086,807 1,093,815 RGD:6480464
G GPNMB glycoprotein nmb JBrowse link 7 23,246,766 23,275,110 RGD:6480464
G GPR18 G protein-coupled receptor 18 JBrowse link 13 99,254,713 99,262,498 RGD:6480464
G GPT glutamic--pyruvic transaminase JBrowse link 8 144,502,217 144,507,174 RGD:6480464
G GSK3B glycogen synthase kinase 3 beta JBrowse link 3 119,821,321 120,095,823 RGD:6480464
G GSTT1 glutathione S-transferase theta 1 RGD:6480464
G GTPBP4 GTP binding protein 4 JBrowse link 10 988,434 1,019,932 RGD:6480464
G GUCA2A guanylate cyclase activator 2A JBrowse link 1 42,162,690 42,164,745 RGD:6480464
G GZMB granzyme B JBrowse link 14 24,630,954 24,634,190 RGD:6480464
G H2AX H2A.X variant histone JBrowse link 11 119,093,874 119,095,465 RGD:6480464
G HAVCR1 hepatitis A virus cellular receptor 1 JBrowse link 5 157,028,383 157,069,633 RGD:6480464
G HBP1 HMG-box transcription factor 1 JBrowse link 7 107,168,961 107,202,529 RGD:6480464
G HES1 hes family bHLH transcription factor 1 JBrowse link 3 194,136,148 194,138,732 RGD:6480464
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 61,695,513 61,748,259 RGD:6480464
G HMGB1 high mobility group box 1 JBrowse link 13 30,456,704 30,617,597 RGD:6480464
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 5 75,336,334 75,362,116 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G HNRNPD heterogeneous nuclear ribonucleoprotein D JBrowse link 4 82,352,498 82,373,996 RGD:6480464
G HOXA9 homeobox A9 JBrowse link 7 27,162,438 27,165,537 RGD:6480464
G HRAS HRas proto-oncogene, GTPase JBrowse link 11 532,242 535,576 RGD:6480464
G HSPA1B heat shock protein family A (Hsp70) member 1B JBrowse link 6 31,827,738 31,830,254 RGD:6480464
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 9 125,234,853 125,241,343 RGD:6480464
G HSPB8 heat shock protein family B (small) member 8 JBrowse link 12 119,178,931 119,194,746 RGD:6480464
G IBSP integrin binding sialoprotein JBrowse link 4 87,799,554 87,812,435 RGD:6480464
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,271,120 10,286,615 RGD:6480464
G ID1 inhibitor of DNA binding 1, HLH protein JBrowse link 20 31,605,289 31,606,510 RGD:6480464
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:6480464
G IGF1 insulin like growth factor 1 JBrowse link 12 102,395,860 102,481,839 RGD:6480464
G IGF1R insulin like growth factor 1 receptor JBrowse link 15 98,648,539 98,964,530 RGD:6480464
G IGFBP1 insulin like growth factor binding protein 1 JBrowse link 7 45,888,488 45,893,660 RGD:6480464
G IGFBP3 insulin like growth factor binding protein 3 JBrowse link 7 45,912,245 45,921,272 RGD:6480464
G IGFBP5 insulin like growth factor binding protein 5 JBrowse link 2 216,672,105 216,695,549 RGD:6480464
G IL10 interleukin 10 JBrowse link 1 206,767,602 206,772,494 RGD:6480464
G IL12A interleukin 12A JBrowse link 3 159,988,835 159,996,019 RGD:6480464
G IL12B interleukin 12B JBrowse link 5 159,314,780 159,330,487 RGD:6480464
G IL17RB interleukin 17 receptor B JBrowse link 3 53,846,550 53,867,388 RGD:6480464
G IL18 interleukin 18 JBrowse link 11 112,143,251 112,164,104 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL2 interleukin 2 JBrowse link 4 122,449,479 122,456,725 RGD:6480464
G IL2RA interleukin 2 receptor subunit alpha JBrowse link 10 6,010,689 6,062,367 RGD:6480464
G IL2RG interleukin 2 receptor subunit gamma JBrowse link X 71,107,404 71,111,577 RGD:6480464
G IL3 interleukin 3 JBrowse link 5 132,060,655 132,063,204 RGD:6480464
G IL4 interleukin 4 JBrowse link 5 132,673,986 132,682,678 RGD:6480464
G IL4R interleukin 4 receptor JBrowse link 16 27,313,668 27,364,778 RGD:6480464
G IL5 interleukin 5 JBrowse link 5 132,539,194 132,556,864 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G ING4 inhibitor of growth family member 4 JBrowse link 12 6,650,301 6,663,143 RGD:6480464
G INS insulin JBrowse link 11 2,159,779 2,161,209 RGD:6480464
G INSIG1 insulin induced gene 1 JBrowse link 7 155,297,772 155,310,235 RGD:6480464
G IRS1 insulin receptor substrate 1 JBrowse link 2 226,731,317 226,798,790 RGD:6480464
G ITGAM integrin subunit alpha M JBrowse link 16 31,259,975 31,332,877 RGD:6480464
G ITGAV integrin subunit alpha V JBrowse link 2 186,590,056 186,680,902 RGD:6480464
G JAG1 jagged canonical Notch ligand 1 JBrowse link 20 10,637,684 10,673,999 RGD:6480464
G JMY junction mediating and regulatory protein, p53 cofactor JBrowse link 5 79,236,131 79,327,215 RGD:6480464
G JUN Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 58,780,791 58,784,047 RGD:6480464
G KIFAP3 kinesin associated protein 3 JBrowse link 1 169,921,326 170,085,203 RGD:6480464
G KIFC1 kinesin family member C1 JBrowse link 6 33,391,524 33,410,226 RGD:6480464
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 4 54,657,928 54,740,715 RGD:6480464
G KITLG KIT ligand JBrowse link 12 88,492,793 88,580,473 RGD:6480464
G KLF2 Kruppel like factor 2 JBrowse link 19 16,324,826 16,328,685 RGD:6480464
G KLF5 Kruppel like factor 5 JBrowse link 13 73,054,976 73,077,542 RGD:6480464
G KLF6 Kruppel like factor 6 JBrowse link 10 3,775,996 3,785,281 RGD:6480464
G KLHL24 kelch like family member 24 JBrowse link 3 183,635,619 183,684,519 RGD:6480464
G KLK2 kallikrein related peptidase 2 JBrowse link 19 50,873,433 50,880,567 RGD:6480464
G KLK3 kallikrein related peptidase 3 JBrowse link 19 50,854,915 50,860,764 RGD:6480464
G L1CAM L1 cell adhesion molecule JBrowse link X 153,861,514 153,886,173 RGD:6480464
G LAMC2 laminin subunit gamma 2 JBrowse link 1 183,186,264 183,245,127 RGD:6480464
G LARP1 La ribonucleoprotein 1, translational regulator JBrowse link 5 154,682,979 154,817,605 RGD:6480464
G LCN2 lipocalin 2 JBrowse link 9 128,149,453 128,153,453 RGD:6480464
G LIPE lipase E, hormone sensitive type JBrowse link 19 42,401,512 42,427,421 RGD:6480464
G MAD2L1 mitotic arrest deficient 2 like 1 JBrowse link 4 120,055,623 120,066,848 RGD:6480464
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha JBrowse link 20 34,546,823 34,560,345 RGD:6480464
G MAP1LC3B microtubule associated protein 1 light chain 3 beta JBrowse link 16 87,392,336 87,404,774 RGD:6480464
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 15 66,386,912 66,491,544 RGD:6480464
G MAP2K2 mitogen-activated protein kinase kinase 2 JBrowse link 19 4,090,321 4,124,184 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MAPK8 mitogen-activated protein kinase 8 JBrowse link 10 48,306,639 48,439,360 RGD:6480464
G MBNL2 muscleblind like splicing regulator 2 JBrowse link 13 97,222,289 97,394,120 RGD:6480464
G MBP myelin basic protein JBrowse link 18 76,978,833 77,133,708 RGD:6480464
G MCL1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 1 150,574,551 150,579,738 RGD:6480464
G MCM2 minichromosome maintenance complex component 2 JBrowse link 3 127,598,411 127,622,436 RGD:6480464
G MCM7 minichromosome maintenance complex component 7 JBrowse link 7 100,092,728 100,101,397 RGD:6480464
G MDM2 MDM2 proto-oncogene JBrowse link 12 68,808,149 68,850,686 RGD:6480464
G MIR122 microRNA 122 JBrowse link 18 58,451,074 58,451,158 RGD:6480464
G MIR132 microRNA 132 JBrowse link 17 2,049,908 2,050,008 RGD:6480464
G MIR146A microRNA 146a JBrowse link 5 160,485,352 160,485,450 RGD:6480464
G MIR151A microRNA 151a JBrowse link 8 140,732,564 140,732,653 RGD:6480464
G MIR181A2 microRNA 181a-2 JBrowse link 9 124,692,442 124,692,551 RGD:6480464
G MIR190A microRNA 190a JBrowse link 15 62,823,957 62,824,041 RGD:6480464
G MIR212 microRNA 212 JBrowse link 17 2,050,271 2,050,380 RGD:6480464
G MIR29C microRNA 29c JBrowse link 1 207,801,852 207,801,939 RGD:6480464
G MIR324 microRNA 324 JBrowse link 17 7,223,297 7,223,379 RGD:6480464
G MIR330 microRNA 330 JBrowse link 19 45,638,994 45,639,087 RGD:6480464
G MIR379 microRNA 379 JBrowse link 14 101,022,066 101,022,132 RGD:6480464
G MIR433 microRNA 433 JBrowse link 14 100,881,886 100,881,978 RGD:6480464
G MIR503 microRNA 503 JBrowse link X 134,546,328 134,546,398 RGD:6480464
G MIR508 microRNA 508 JBrowse link X 147,236,913 147,237,027 RGD:6480464
G MIR650 microRNA 650 JBrowse link 22 22,822,776 22,822,871 RGD:6480464
G MIR654 microRNA 654 JBrowse link 14 101,040,219 101,040,299 RGD:6480464
G MIR758 microRNA 758 JBrowse link 14 101,026,020 101,026,107 RGD:6480464
G MIR760 microRNA 760 JBrowse link 1 93,846,832 93,846,911 RGD:6480464
G MKI67 marker of proliferation Ki-67 JBrowse link 10 128,096,659 128,126,423 RGD:6480464
G MLST8 MTOR associated protein, LST8 homolog JBrowse link 16 2,204,628 2,209,453 RGD:6480464
G MMP1 matrix metallopeptidase 1 JBrowse link 11 102,789,919 102,798,160 RGD:6480464
G MMP2 matrix metallopeptidase 2 JBrowse link 16 55,478,830 55,506,691 RGD:6480464
G MMP9 matrix metallopeptidase 9 JBrowse link 20 46,008,908 46,016,561 RGD:6480464
G MPZ myelin protein zero JBrowse link 1 161,303,594 161,309,969 RGD:6480464
G MSR1 macrophage scavenger receptor 1 JBrowse link 8 16,107,878 16,192,791 RGD:6480464
G MT1E metallothionein 1E JBrowse link 16 56,625,781 56,627,112 RGD:6480464
G MT1G metallothionein 1G JBrowse link 16 56,666,730 56,668,065 RGD:6480464
G MT1H metallothionein 1H JBrowse link 16 56,669,814 56,671,129 RGD:6480464
G MT1M metallothionein 1M JBrowse link 16 56,632,659 56,633,981 RGD:6480464
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 11,106,535 11,273,497 RGD:6480464
G MTURN maturin, neural progenitor differentiation regulator homolog JBrowse link 7 30,134,986 30,162,764 RGD:6480464
G MYBL2 MYB proto-oncogene like 2 JBrowse link 20 43,667,019 43,716,496 RGD:6480464
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 8 127,735,434 127,742,951 RGD:6480464
G MYH11 myosin heavy chain 11 JBrowse link 16 15,703,135 15,857,032 RGD:6480464
G MYH7 myosin heavy chain 7 JBrowse link 14 23,412,740 23,435,677 RGD:6480464
G MYLK myosin light chain kinase JBrowse link 3 123,610,049 123,884,332 RGD:6480464
G MYOF myoferlin JBrowse link 10 93,306,429 93,482,505 RGD:6480464
G NAIP NLR family apoptosis inhibitory protein JBrowse link 5 70,968,166 71,025,339 RGD:6480464
G NANOG Nanog homeobox JBrowse link 12 7,789,402 7,799,146 RGD:6480464
G NCF1 neutrophil cytosolic factor 1 JBrowse link 7 74,773,962 74,789,376 RGD:6480464
G NCF2 neutrophil cytosolic factor 2 JBrowse link 1 183,555,562 183,590,914 RGD:6480464
G NCF4 neutrophil cytosolic factor 4 JBrowse link 22 36,860,988 36,878,017 RGD:6480464
G NDC80 NDC80 kinetochore complex component JBrowse link 18 2,571,557 2,616,635 RGD:6480464
G NEK2 NIMA related kinase 2 JBrowse link 1 211,658,256 211,675,630 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NFKB1 nuclear factor kappa B subunit 1 JBrowse link 4 102,501,266 102,617,302 RGD:6480464
G NFKBIA NFKB inhibitor alpha JBrowse link 14 35,401,513 35,404,749 RGD:6480464
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 247,416,156 247,449,108 RGD:6480464
G NME1 NME/NM23 nucleoside diphosphate kinase 1 JBrowse link 17 51,153,559 51,162,089 RGD:6480464
G NMU neuromedin U JBrowse link 4 55,595,231 55,636,793 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6480464
G NOS3 nitric oxide synthase 3 JBrowse link 7 150,991,017 151,014,588 RGD:6480464
G NPHS2 NPHS2 stomatin family member, podocin JBrowse link 1 179,550,539 179,575,987 RGD:6480464
G NPPA natriuretic peptide A JBrowse link 1 11,845,709 11,847,783 RGD:6480464
G NPPB natriuretic peptide B JBrowse link 1 11,857,464 11,858,945 RGD:6480464
G NR1H3 nuclear receptor subfamily 1 group H member 3 JBrowse link 11 47,248,300 47,269,033 RGD:6480464
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:6480464
G NR3C1 nuclear receptor subfamily 3 group C member 1 JBrowse link 5 143,277,931 143,435,512 RGD:6480464
G NR5A1 nuclear receptor subfamily 5 group A member 1 JBrowse link 9 124,481,236 124,507,399 RGD:6480464
G NXT1 nuclear transport factor 2 like export factor 1 JBrowse link 20 23,350,791 23,354,771 RGD:6480464
G OGN osteoglycin JBrowse link 9 92,383,268 92,404,699 RGD:6480464
G OLR1 oxidized low density lipoprotein receptor 1 JBrowse link 12 10,158,300 10,172,191 RGD:6480464
G OXA1L OXA1L mitochondrial inner membrane protein JBrowse link 14 22,766,688 22,773,042 RGD:6480464
G PABPC1 poly(A) binding protein cytoplasmic 1 JBrowse link 8 100,702,916 100,722,088 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PAX8 paired box 8 JBrowse link 2 113,215,997 113,278,921 RGD:6480464
G PCK1 phosphoenolpyruvate carboxykinase 1 JBrowse link 20 57,561,110 57,568,121 RGD:6480464
G PCNA proliferating cell nuclear antigen JBrowse link 20 5,114,953 5,126,622 RGD:6480464
G PDCD4 programmed cell death 4 JBrowse link 10 110,871,795 110,900,006 RGD:6480464
G PDGFB platelet derived growth factor subunit B JBrowse link 22 39,223,359 39,244,982 RGD:6480464
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 179,148,114 179,240,093 RGD:6480464
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 5 68,215,737 68,301,821 RGD:6480464
G PIM1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 6 37,170,152 37,175,428 RGD:6480464
G PKM pyruvate kinase M1/2 JBrowse link 15 72,199,029 72,231,624 RGD:6480464
G PKP4 plakophilin 4 JBrowse link 2 158,456,880 158,682,890 RGD:6480464
G PLCL1 phospholipase C like 1 (inactive) JBrowse link 2 197,804,593 198,149,873 RGD:6480464
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 59,899,996 59,904,305 RGD:6480464
G PML promyelocytic leukemia JBrowse link 15 73,994,673 74,047,827 RGD:6480464
G PMP22 peripheral myelin protein 22 JBrowse link 17 15,229,777 15,265,326 RGD:6480464
G PNPLA2 patatin like phospholipase domain containing 2 JBrowse link 11 818,890 825,573 RGD:6480464
G PNRC1 proline rich nuclear receptor coactivator 1 JBrowse link 6 89,080,749 89,085,160 RGD:6480464
G POLD2 DNA polymerase delta 2, accessory subunit JBrowse link 7 44,114,680 44,123,668 RGD:6480464
G POSTN periostin JBrowse link 13 37,562,582 37,598,844 RGD:6480464
G POU5F1 POU class 5 homeobox 1 JBrowse link 6 31,164,337 31,170,682 RGD:6480464
G PPARA peroxisome proliferator activated receptor alpha JBrowse link 22 46,150,526 46,243,756 RGD:6480464
G PPARD peroxisome proliferator activated receptor delta JBrowse link 6 35,342,558 35,428,191 RGD:6480464
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 3 12,287,485 12,434,344 RGD:6480464
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 4 23,792,021 24,472,905 RGD:6480464
G PPL periplakin JBrowse link 16 4,882,507 4,937,148 RGD:6480464
G PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B JBrowse link 17 39,626,735 39,636,625 RGD:6480464
G PPP2R1B protein phosphatase 2 scaffold subunit Abeta JBrowse link 11 111,690,273 111,766,389 RGD:6480464
G PRCP prolylcarboxypeptidase JBrowse link 11 82,822,936 82,901,740 RGD:6480464
G PRF1 perforin 1 JBrowse link 10 70,597,348 70,602,788 RGD:6480464
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 5 40,759,379 40,798,195 RGD:6480464
G PRKCA protein kinase C alpha JBrowse link 17 66,302,613 66,810,743 RGD:6480464
G PRKCD protein kinase C delta JBrowse link 3 53,161,209 53,192,717 RGD:6480464
G PRKCG protein kinase C gamma JBrowse link 19 53,882,197 53,907,652 RGD:6480464
G PRKCH protein kinase C eta JBrowse link 14 61,187,305 61,550,980 RGD:6480464
G PRLR prolactin receptor JBrowse link 5 35,048,756 35,230,724 RGD:6480464
G PSMA1 proteasome 20S subunit alpha 1 JBrowse link 11 14,504,876 14,643,634 RGD:6480464
G PSMA4 proteasome 20S subunit alpha 4 JBrowse link 15 78,540,405 78,552,417 RGD:6480464
G PSMD11 proteasome 26S subunit, non-ATPase 11 JBrowse link 17 32,444,510 32,483,319 RGD:6480464
G PTEN phosphatase and tensin homolog JBrowse link 10 87,863,625 87,971,930 RGD:6480464
G PTGER1 prostaglandin E receptor 1 JBrowse link 19 14,472,466 14,475,354 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G PTK2 protein tyrosine kinase 2 JBrowse link 8 140,657,900 141,002,079 RGD:6480464
G PTPN5 protein tyrosine phosphatase non-receptor type 5 JBrowse link 11 18,727,928 18,792,721 RGD:6480464
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 198,638,968 198,757,476 RGD:6480464
G PTTG1 PTTG1 regulator of sister chromatid separation, securin JBrowse link 5 160,421,855 160,428,744 RGD:6480464
G RAC1 Rac family small GTPase 1 JBrowse link 7 6,374,527 6,403,967 RGD:6480464
G RAD51 RAD51 recombinase JBrowse link 15 40,694,774 40,732,340 RGD:6480464
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 3 12,583,601 12,664,201 RGD:6480464
G RB1 RB transcriptional corepressor 1 JBrowse link 13 48,303,747 48,481,890 RGD:6480464
G RBL1 RB transcriptional corepressor like 1 JBrowse link 20 36,996,349 37,096,029 RGD:6480464
G RBL2 RB transcriptional corepressor like 2 JBrowse link 16 53,434,471 53,491,648 RGD:6480464
G RCAN1 regulator of calcineurin 1 JBrowse link 21 34,516,442 34,615,123 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G REN renin JBrowse link 1 204,154,819 204,166,337 RGD:6480464
G REST RE1 silencing transcription factor JBrowse link 4 56,907,900 56,935,847 RGD:6480464
G RICTOR RPTOR independent companion of MTOR complex 2 JBrowse link 5 38,937,920 39,074,421 RGD:6480464
G RPL32 ribosomal protein L32 JBrowse link 3 12,834,485 12,841,582 RGD:6480464
G RPL7P26 ribosomal protein L7 pseudogene 26 JBrowse link 6 17,530,828 17,531,457 RGD:6480464
G RPS20 ribosomal protein S20 JBrowse link 8 56,067,295 56,074,581 RGD:6480464
G RPS27L ribosomal protein S27 like JBrowse link 15 63,148,249 63,157,477 RGD:6480464
G RPS6 ribosomal protein S6 JBrowse link 9 19,375,715 19,380,236 RGD:6480464
G RPS6KA1 ribosomal protein S6 kinase A1 JBrowse link 1 26,529,761 26,575,028 RGD:6480464
G RPS6KA2 ribosomal protein S6 kinase A2 JBrowse link 6 166,409,364 166,862,525 RGD:6480464
G RPS6KA3 ribosomal protein S6 kinase A3 JBrowse link X 20,149,911 20,267,514 RGD:6480464
G RPS6KB1 ribosomal protein S6 kinase B1 JBrowse link 17 59,893,046 59,950,574 RGD:6480464
G RPS6KB2 ribosomal protein S6 kinase B2 JBrowse link 11 67,428,475 67,435,408 RGD:6480464
G RPTOR regulatory associated protein of MTOR complex 1 JBrowse link 17 80,544,838 80,966,368 RGD:6480464
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator JBrowse link 16 66,921,679 66,925,536 RGD:6480464
G RTN4 reticulon 4 JBrowse link 2 54,972,189 55,137,831 RGD:6480464
G RTN4R reticulon 4 receptor JBrowse link 22 20,241,415 20,268,318 RGD:6480464
G S100A4 S100 calcium binding protein A4 JBrowse link 1 153,543,621 153,545,806 RGD:6480464
G S100G S100 calcium binding protein G JBrowse link X 16,649,787 16,654,674 RGD:6480464
G S1PR1 sphingosine-1-phosphate receptor 1 JBrowse link 1 101,236,749 101,241,520 RGD:6480464
G SCARB2 scavenger receptor class B member 2 JBrowse link 4 76,158,737 76,213,824 RGD:6480464
G SCARNA23 small Cajal body-specific RNA 23 JBrowse link X 24,744,441 24,744,570 RGD:6480464
G SCD stearoyl-CoA desaturase JBrowse link 10 100,347,233 100,364,826 RGD:6480464
G SEMA3A semaphorin 3A JBrowse link 7 83,955,777 84,515,189 RGD:6480464
G SEMA3C semaphorin 3C JBrowse link 7 80,742,536 80,922,389 RGD:6480464
G SERPINA1 serpin family A member 1 JBrowse link 14 94,376,747 94,390,654 RGD:6480464
G SERPINE1 serpin family E member 1 JBrowse link 7 101,127,104 101,139,247 RGD:6480464
G SESN2 sestrin 2 JBrowse link 1 28,259,452 28,282,491 RGD:6480464
G SHISA2 shisa family member 2 JBrowse link 13 26,044,597 26,052,016 RGD:6480464
G SIRT1 sirtuin 1 JBrowse link 10 67,884,656 67,918,390 RGD:6480464
G SIRT2 sirtuin 2 JBrowse link 19 38,878,555 38,899,862 RGD:6480464
G SKP2 S-phase kinase associated protein 2 JBrowse link 5 36,152,043 36,184,319 RGD:6480464
G SLC12A1 solute carrier family 12 member 1 JBrowse link 15 48,206,302 48,304,078 RGD:6480464
G SLC12A3 solute carrier family 12 member 3 JBrowse link 16 56,865,207 56,915,850 RGD:6480464
G SLC15A1 solute carrier family 15 member 1 JBrowse link 13 98,683,801 98,752,672 RGD:6480464
G SLC16A1 solute carrier family 16 member 1 JBrowse link 1 112,911,847 112,956,196 RGD:6480464
G SLC22A13 solute carrier family 22 member 13 JBrowse link 3 38,265,812 38,278,757 RGD:6480464
G SLC5A1 solute carrier family 5 member 1 JBrowse link 22 32,043,050 32,113,029 RGD:6480464
G SMIM14 small integral membrane protein 14 JBrowse link 4 39,546,336 39,638,865 RGD:6480464
G SNAI1 snail family transcriptional repressor 1 JBrowse link 20 49,982,980 49,988,886 RGD:6480464
G SOX2 SRY-box transcription factor 2 JBrowse link 3 181,711,925 181,714,436 RGD:6480464
G SPP1 secreted phosphoprotein 1 JBrowse link 4 87,975,650 87,983,411 RGD:6480464
G SQSTM1 sequestosome 1 JBrowse link 5 179,806,393 179,838,078 RGD:6480464
G SRC SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 20 37,344,685 37,405,432 RGD:6480464
G SREBF1 sterol regulatory element binding transcription factor 1 JBrowse link 17 17,811,334 17,837,017 RGD:6480464
G SRR serine racemase JBrowse link 17 2,303,371 2,325,267 RGD:6480464
G STARD10 StAR related lipid transfer domain containing 10 JBrowse link 11 72,754,729 72,793,705 RGD:6480464
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 42,313,324 42,388,502 RGD:6480464
G STS steroid sulfatase JBrowse link X 7,147,290 7,354,641 RGD:6480464
G SYT1 synaptotagmin 1 JBrowse link 12 78,863,982 79,452,008 RGD:6480464
G TAF12 TATA-box binding protein associated factor 12 JBrowse link 1 28,602,850 28,648,707 RGD:6480464
G TAL1 TAL bHLH transcription factor 1, erythroid differentiation factor JBrowse link 1 47,216,290 47,232,389 RGD:6480464
G TARS1 threonyl-tRNA synthetase 1 JBrowse link 5 33,440,696 33,468,091 RGD:6480464
G TAX1BP1 Tax1 binding protein 1 JBrowse link 7 27,739,373 27,829,767 RGD:6480464
G TCF19 transcription factor 19 JBrowse link 6 31,158,589 31,164,215 RGD:6480464
G TEAD1 TEA domain transcription factor 1 JBrowse link 11 12,674,421 12,944,737 RGD:6480464
G TERT telomerase reverse transcriptase JBrowse link 5 1,253,148 1,295,068 RGD:6480464
G TFEB transcription factor EB JBrowse link 6 41,683,978 41,736,223 RGD:6480464
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6480464
G TGFBR3 transforming growth factor beta receptor 3 JBrowse link 1 91,680,343 91,906,002 RGD:6480464
G TGM2 transglutaminase 2 JBrowse link 20 38,127,385 38,166,508 RGD:6480464
G TIMELESS timeless circadian regulator JBrowse link 12 56,416,363 56,449,426 RGD:6480464
G TIMP3 TIMP metallopeptidase inhibitor 3 JBrowse link 22 32,800,816 32,863,041 RGD:6480464
G TMEM14C transmembrane protein 14C JBrowse link 6 10,722,915 10,731,129 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TNFSF11 TNF superfamily member 11 JBrowse link 13 42,562,736 42,608,013 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464
G TP63 tumor protein p63 JBrowse link 3 189,596,746 189,897,279 RGD:6480464
G TP73 tumor protein p73 JBrowse link 1 3,652,516 3,736,201 RGD:6480464
G TPP2 tripeptidyl peptidase 2 JBrowse link 13 102,596,985 102,679,958 RGD:6480464
G TRIB3 tribbles pseudokinase 3 JBrowse link 20 380,629 397,559 RGD:6480464
G TRPM6 transient receptor potential cation channel subfamily M member 6 JBrowse link 9 74,722,495 74,887,921 RGD:6480464
G TSC1 TSC complex subunit 1 JBrowse link 9 132,891,349 132,945,269 RGD:6480464
G TSC2 TSC complex subunit 2 JBrowse link 16 2,047,804 2,089,491 RGD:6480464
G TTK TTK protein kinase JBrowse link 6 80,004,147 80,042,651 RGD:6480464
G TYMS thymidylate synthetase JBrowse link 18 657,653 673,578 RGD:6480464
G ULK1 unc-51 like autophagy activating kinase 1 JBrowse link 12 131,894,622 131,923,150 RGD:6480464
G URI1 URI1 prefoldin like chaperone JBrowse link 19 29,923,650 30,016,612 RGD:6480464
G VASN vasorin JBrowse link 16 4,371,848 4,383,538 RGD:6480464
G VCAN versican JBrowse link 5 83,471,674 83,582,303 RGD:6480464
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:6480464
G VIM vimentin JBrowse link 10 17,228,241 17,237,593 RGD:6480464
G WT1 WT1 transcription factor JBrowse link 11 32,387,775 32,435,539 RGD:6480464
G XBP1 X-box binding protein 1 JBrowse link 22 28,794,560 28,800,572 RGD:6480464
G XIAP X-linked inhibitor of apoptosis JBrowse link X 123,859,812 123,913,979 RGD:6480464
G YPEL1 yippee like 1 JBrowse link 22 21,697,536 21,735,794 RGD:6480464
G ZBED8 zinc finger BED-type containing 8 JBrowse link 5 160,393,148 160,400,097 RGD:6480464
G ZIC2 Zic family member 2 JBrowse link 13 99,981,784 99,986,765 RGD:6480464
G ZNF628 zinc finger protein 628 JBrowse link 19 55,476,603 55,484,487 RGD:6480464
G ZNRD1 zinc ribbon domain containing 1 JBrowse link 6 30,061,265 30,064,907 RGD:6480464
G ZWINT ZW10 interacting kinetochore protein JBrowse link 10 56,357,227 56,361,273 RGD:6480464
everolimus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
G ABCB11 ATP binding cassette subfamily B member 11 JBrowse link 2 168,915,468 169,031,396 RGD:6480464
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) JBrowse link 4 88,090,264 88,231,626 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 17 78,214,253 78,225,635 RGD:6480464
G BRD4 bromodomain containing 4 JBrowse link 19 15,236,836 15,332,539 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CCNA2 cyclin A2 JBrowse link 4 121,816,444 121,823,883 RGD:6480464
G CCND1 cyclin D1 JBrowse link 11 69,641,156 69,654,474 RGD:6480464
G CCND2 cyclin D2 JBrowse link 12 4,273,762 4,305,353 RGD:6480464
G CCND3 cyclin D3 JBrowse link 6 41,934,933 42,048,894 RGD:6480464
G CDH1 cadherin 1 JBrowse link 16 68,737,292 68,835,537 RGD:6480464
G CES1 carboxylesterase 1 JBrowse link 16 55,802,851 55,833,127 RGD:6480464
G CES2 carboxylesterase 2 JBrowse link 16 66,934,471 66,945,096 RGD:6480464
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:6480464
G EIF4E eukaryotic translation initiation factor 4E JBrowse link 4 98,871,684 98,930,637 RGD:6480464
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 8 38,030,534 38,060,365 RGD:6480464
G EIF4G1 eukaryotic translation initiation factor 4 gamma 1 JBrowse link 3 184,314,495 184,335,358 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 1 94,529,173 94,541,857 RGD:6480464
G IGF1R insulin like growth factor 1 receptor JBrowse link 15 98,648,539 98,964,530 RGD:6480464
G ITGAM integrin subunit alpha M JBrowse link 16 31,259,975 31,332,877 RGD:6480464
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 11,106,535 11,273,497 RGD:6480464
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 8 127,735,434 127,742,951 RGD:6480464
G NGF nerve growth factor JBrowse link 1 115,285,915 115,338,253 RGD:6480464
G NOS3 nitric oxide synthase 3 JBrowse link 7 150,991,017 151,014,588 RGD:6480464
G NR1I3 nuclear receptor subfamily 1 group I member 3 JBrowse link 1 161,229,666 161,238,623 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G PTK2 protein tyrosine kinase 2 JBrowse link 8 140,657,900 141,002,079 RGD:6480464
G RB1 RB transcriptional corepressor 1 JBrowse link 13 48,303,747 48,481,890 RGD:6480464
G RHOA ras homolog family member A JBrowse link 3 49,359,145 49,411,976 RGD:6480464
G RPS6 ribosomal protein S6 JBrowse link 9 19,375,715 19,380,236 RGD:6480464
G RPS6KB1 ribosomal protein S6 kinase B1 JBrowse link 17 59,893,046 59,950,574 RGD:6480464
G SIRT1 sirtuin 1 JBrowse link 10 67,884,656 67,918,390 RGD:6480464
G SRC SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 20 37,344,685 37,405,432 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G VIM vimentin JBrowse link 10 17,228,241 17,237,593 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23754
    role 23643
      biological role 23606
        immunomodulator 14918
          immunosuppressive agent 12870
            sirolimus 470
              everolimus 37
              ridaforolimus 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  main group element atom 23522
                    p-block element atom 23522
                      carbon group element atom 23232
                        carbon atom 23208
                          organic molecular entity 23208
                            organic group 21894
                              organic divalent group 21866
                                organodiyl group 21866
                                  carbonyl group 21838
                                    carbonyl compound 21838
                                      carboxylic acid 20881
                                        carboacyl group 18971
                                          univalent carboacyl group 18971
                                            carbamoyl group 18357
                                              carboxamide 18357
                                                lactam 8144
                                                  macrolide lactam 0
                                                    sirolimus 470
                                                      everolimus 37
                                                      ridaforolimus 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.