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ONTOLOGY REPORT - ANNOTATIONS


Term:terbutaline
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Accession:CHEBI:9449 term browser browse the term
Definition:A member of the class of phenylethanolamines that is catechol substuted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.
Synonyms:exact_synonym: 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol
 related_synonym: Formula=C12H19NO3;   InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8/h4-6,11,13-16H,7H2,1-3H3;   InChIKey=XWTYSIMOBUGWOL-UHFFFAOYSA-N;   SMILES=CC(C)(C)NCC(O)c1cc(O)cc(O)c1;   terbutalina;   terbutalinum
 xref: CAS:23031-25-6 "KEGG COMPOUND";   DrugBank:DB00871;   Drug_Central:2598 "DrugCentral";   HMDB:HMDB0015009;   KEGG:C07129;   KEGG:D08570
 xref_mesh: MESH:D013726
 xref: PMID:12423672 "Europe PMC";   PMID:12569076 "Europe PMC";   PMID:21618259 "Europe PMC";   PMID:21996060 "Europe PMC";   PMID:22310877 "Europe PMC";   PMID:22363704 "Europe PMC";   PMID:22765375 "Europe PMC";   PMID:22767151 "Europe PMC";   PMID:22782385 "Europe PMC";   PMID:22813780 "Europe PMC";   PMID:22872661 "Europe PMC";   PMID:22988932 "Europe PMC";   PMID:23075357 "Europe PMC";   PMID:23126237 "Europe PMC";   PMID:23204625 "Europe PMC";   PMID:23283786 "Europe PMC";   PMID:23299764 "Europe PMC";   PMID:23325598 "Europe PMC";   PMID:23341043 "Europe PMC";   PMID:8298802 "Europe PMC";   PMID:9596106 "Europe PMC";   Patent:WO2011112499;   Reaxys:2370513 "Reaxys";   Wikipedia:Terbutaline


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terbutaline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:6480464
G Adra1d adrenoceptor alpha 1D JBrowse link 3 124,129,558 124,145,566 RGD:6480464
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6480464
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:6480464
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:6480464
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:6480464
G Aoc1 amine oxidase, copper containing 1 JBrowse link 4 78,496,043 78,515,582 RGD:6480464
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:6480464
G Aqp5 aquaporin 5 JBrowse link 7 141,249,044 141,252,576 RGD:6480464
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Chat choline O-acetyltransferase JBrowse link 16 8,576,858 8,686,131 RGD:6480464
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:6480464
G Csk C-terminal Src kinase JBrowse link 8 62,405,714 62,424,707 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Gast gastrin JBrowse link 10 88,245,532 88,248,485 RGD:6480464
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:6480464
G Nefl neurofilament light JBrowse link 15 44,799,378 44,803,251 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:6480464
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:6480464
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 JBrowse link 10 61,456,144 61,577,412 RGD:6480464
G Phgdh phosphoglycerate dehydrogenase JBrowse link 2 200,484,245 200,513,564 RGD:6480464
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:6480464
G Scnn1a sodium channel epithelial 1 subunit alpha JBrowse link 4 157,834,339 157,860,472 RGD:6480464
G Scnn1b sodium channel epithelial 1 subunit beta JBrowse link 1 191,829,547 191,883,991 RGD:6480464
G Scnn1g sodium channel epithelial 1 subunit gamma JBrowse link 1 191,704,397 191,738,271 RGD:6480464
G Sftpb surfactant protein B JBrowse link 4 100,166,855 100,175,941 RGD:6480464
G Sftpc surfactant protein C JBrowse link 15 52,211,538 52,214,480 RGD:6480464
G Sftpd surfactant protein D JBrowse link 16 18,753,535 18,766,100 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Sst somatostatin JBrowse link 11 80,358,172 80,359,449 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Usf1 upstream transcription factor 1 JBrowse link 13 89,797,750 89,805,561 RGD:6480464
bambuterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        anti-asthmatic agent 9171
          anti-asthmatic drug 8547
            terbutaline 52
              bambuterol + 2
              terbutaline sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    main group molecular entity 19610
                      s-block molecular entity 19378
                        hydrogen molecular entity 19367
                          hydrides 18278
                            inorganic hydride 17205
                              pnictogen hydride 17167
                                nitrogen hydride 17003
                                  azane 16694
                                    ammonia 16691
                                      organic amino compound 16690
                                        amino alcohol 867
                                          ethanolamines 757
                                            phenylethanolamines 576
                                              terbutaline 52
                                                bambuterol + 2
                                                terbutaline sulfate 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.