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Accession:CHEBI:9613 term browser browse the term
Definition:An N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus.
Synonyms:exact_synonym: N-(azepan-1-ylcarbamoyl)-4-methylbenzenesulfonamide
 related_synonym: 1-(hexahydro-1-azepinyl)-3-p-tolylsulfonylurea;   1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea;   4-(p-tolylsulfonyl)-1,1-hexamethylenesemicarbazide;   BRN 1323565;   CCRIS 591;   Diabewas;   EINECS 214-588-3;   Formula=C14H21N3O3S;   InChI=1S/C14H21N3O3S/c1-12-6-8-13(9-7-12)21(19,20)16-14(18)15-17-10-4-2-3-5-11-17/h6-9H,2-5,10-11H2,1H3,(H2,15,16,18);   InChIKey=OUDSBRTVNLOZBN-UHFFFAOYSA-N;   N-(p-toluenesulfonyl)-N'-hexamethyleniminourea;   N-{[(hexahydro-1H-azepin-1-yl)-amino]carbonyl}-4-methylbenzenesulfonamide;   Norglycin;   SMILES=Cc1ccc(cc1)S(=O)(=O)NC(=O)NN1CCCCCC1;   Tolinase;   U-17835;   tolazamida;   tolazamidum
 xref: CAS:1156-19-0;   DrugBank:DB00839;   Drug_Central:2694;   HMDB:HMDB0014977;   KEGG:D00379;   LINCS:LSM-2699
 xref_mesh: MESH:D014042
 xref: PMID:15901207;   PMID:8237731;   Patent:GB887886;   Reaxys:1323565;   Wikipedia:Tolazamide

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  CHEBI ontology 19758
    role 19705
      application 19359
        pharmaceutical 19228
          drug 19228
            hypoglycemic agent 4001
              tolazamide 0
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  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic group 18428
                              organic divalent group 18419
                                organodiyl group 18419
                                  carbonyl group 18309
                                    carbonyl compound 18309
                                      carboxylic acid 17978
                                        carboacyl group 17095
                                          univalent carboacyl group 17095
                                            carbamoyl group 16818
                                              carboxamide 16818
                                                monocarboxylic acid amide 14185
                                                  urea 4969
                                                    ureas 4966
                                                      N-sulfonylurea 103
                                                        tolazamide 0
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