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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:triforine
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Accession:CHEBI:9715 term browser browse the term
Definition:A member of the class of N-alkylpiperazines in which the two amino groups of piperazine are replaced by 1-formamido-2,2,2-trichloroethyl groups. A fungicide active against a range of diseases including powdery mildew, scab and rust.
Synonyms:exact_synonym: N,N'-[piperazine-1,4-diylbis(2,2,2-trichloroethane-1,1-diyl)]diformamide
 related_synonym: 1,4-Bis(1-formamido-2,2,2-trichloroethyl)piperazine;   1,4-Bis(2,2,2-trichloro-1-formamidoethyl)piperazine;   Biformylchlorazin;   Formula=C10H14Cl6N4O2;   Funginex;   InChI=1S/C10H14Cl6N4O2/c11-9(12,13)7(17-5-21)19-1-2-20(4-3-19)8(18-6-22)10(14,15)16/h5-8H,1-4H2,(H,17,21)(H,18,22);   InChIKey=RROQIUMZODEXOR-UHFFFAOYSA-N;   N,N'-(1,4-Piperazinediylbis(2,2,2-trichloroethylidene))bisformamide;   N,N'-(Piperazine-1,4-diylbis((trichloromethyl)methylene))diformamide;   SMILES=ClC(Cl)(Cl)C(NC=O)N1CCN(CC1)C(NC=O)C(Cl)(Cl)Cl
 xref: CAS:26644-46-2;   KEGG:C10960
 xref_mesh: MESH:C012591
 xref: PMID:1002932;   PMID:1267484;   PMID:15052559;   PMID:24122157;   PMID:2471555;   PMID:597629;   PMID:680740;   PMID:7821004;   PMID:890154;   PPDB:669;   Patent:EP0031454;   Patent:US3975527;   Pesticides:triforine;   Reaxys:626358


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triforine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO triforine binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
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Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        aetiopathogenetic role 18960
          allergen 16942
            triforine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        carboacyl group 17372
                                          univalent carboacyl group 17372
                                            carbamoyl group 17158
                                              carboxamide 17158
                                                formamides 1347
                                                  triforine 1
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