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ONTOLOGY REPORT - ANNOTATIONS


Term:venlafaxine
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Accession:CHEBI:9943 term browser browse the term
Definition:A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-methoxyphenyl group.
Synonyms:exact_synonym: 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol
 related_synonym: Elafax;   Formula=C17H27NO2;   InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3;   InChIKey=PNVNVHUZROJLTJ-UHFFFAOYSA-N;   SMILES=COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1;   venlafaxina;   venlafaxinum
 xref: Beilstein:4234848 "Beilstein";   CAS:93413-69-5 "ChemIDplus";   CAS:93413-69-5 "KEGG COMPOUND";   DrugBank:DB00285;   Drug_Central:2813 "DrugCentral";   HMDB:HMDB0005016;   KEGG:C07187;   KEGG:D08670;   LINCS:LSM-1616
 xref_mesh: MESH:C047426
 xref: PMID:11098420 "Europe PMC";   PMID:12409680 "Europe PMC";   PMID:18321472 "Europe PMC";   Reaxys:4234848 "Reaxys";   Wikipedia:Venlafaxine


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venlafaxine hydrochloride term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:6480464
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:6480464
G Acp5 acid phosphatase 5, tartrate resistant JBrowse link 8 23,142,733 23,149,067 RGD:6480464
G Acvr1c activin A receptor type 1C JBrowse link 3 44,272,859 44,342,501 RGD:6480464
G Adam10 ADAM metallopeptidase domain 10 JBrowse link 8 77,107,355 77,237,483 RGD:6480464
G Adgrl1 adhesion G protein-coupled receptor L1 JBrowse link 19 25,029,037 25,069,146 RGD:6480464
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Akap5 A-kinase anchoring protein 5 JBrowse link 6 99,356,509 99,361,909 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Alcam activated leukocyte cell adhesion molecule JBrowse link 11 50,780,735 50,985,083 RGD:6480464
G Ankrd55 ankyrin repeat domain 55 JBrowse link 2 43,819,234 44,196,602 RGD:6480464
G Ap2b1 adaptor related protein complex 2 subunit beta 1 JBrowse link 10 70,516,462 70,621,973 RGD:6480464
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:6480464
G Arf3 ADP-ribosylation factor 3 JBrowse link 7 140,412,463 140,438,751 RGD:6480464
G Arhgap10 Rho GTPase activating protein 10 JBrowse link 19 34,138,978 34,406,593 RGD:6480464
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 JBrowse link X 64,249,576 64,428,444 RGD:6480464
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:6480464
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 JBrowse link X 157,236,400 157,312,028 RGD:6480464
G Atrx ATRX, chromatin remodeler JBrowse link X 76,820,110 76,979,155 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Brinp3 BMP/retinoic acid inducible neural specific 3 JBrowse link 13 63,526,486 63,959,390 RGD:6480464
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 JBrowse link 3 37,950,846 38,211,478 RGD:6480464
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:6480464
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:6480464
G Camk2b calcium/calmodulin-dependent protein kinase II beta JBrowse link 14 86,208,876 86,297,727 RGD:6480464
G Camk2g calcium/calmodulin-dependent protein kinase II gamma JBrowse link 15 3,936,721 3,995,740 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cd47 Cd47 molecule JBrowse link 11 53,511,485 53,575,754 RGD:6480464
G Cdh22 cadherin 22 JBrowse link 3 161,574,993 161,971,102 RGD:6480464
G Celf2 CUGBP, Elav-like family member 2 JBrowse link 17 75,259,269 75,660,154 RGD:6480464
G Clns1a chloride nucleotide-sensitive channel 1A JBrowse link 1 162,676,246 162,696,549 RGD:6480464
G Clstn2 calsyntenin 2 JBrowse link 8 105,322,577 106,036,821 RGD:6480464
G Cnbp CCHC-type zinc finger, nucleic acid binding protein JBrowse link 4 119,747,890 119,756,787 RGD:6480464
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:6480464
G Cntn2 contactin 2 JBrowse link 13 49,280,913 49,314,061 RGD:6480464
G Cox17 cytochrome c oxidase copper chaperone COX17 JBrowse link 11 64,962,663 64,968,437 RGD:6480464
G Cpd carboxypeptidase D JBrowse link 10 63,325,764 63,389,811 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Cxxc4 CXXC finger protein 4 JBrowse link 2 239,414,882 239,439,640 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:6480464
G Ddah1 dimethylarginine dimethylaminohydrolase 1 JBrowse link 2 251,634,368 251,766,009 RGD:6480464
G Dmac1 distal membrane arm assembly complex 1 JBrowse link 5 92,038,050 92,039,146 RGD:6480464
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link 6 28,205,375 28,346,052 RGD:6480464
G Dpp4 dipeptidylpeptidase 4 JBrowse link 3 48,291,055 48,372,672 RGD:6480464
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:6480464
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:6480464
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:6480464
G Fmnl1 formin-like 1 JBrowse link 10 91,253,757 91,281,422 RGD:6480464
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 JBrowse link 14 38,631,192 39,112,598 RGD:6480464
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 JBrowse link 10 27,973,694 28,193,072 RGD:6480464
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:6480464
G Gas2 growth arrest-specific 2 JBrowse link 1 107,234,389 107,363,624 RGD:6480464
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:6480464
G Gda guanine deaminase JBrowse link 1 238,982,542 239,057,663 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Glp1r glucagon-like peptide 1 receptor JBrowse link 20 9,586,075 9,626,228 RGD:6480464
G Gnao1 G protein subunit alpha o1 JBrowse link 19 11,513,201 11,669,578 RGD:6480464
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:6480464
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:6480464
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 JBrowse link X 127,561,843 127,829,763 RGD:6480464
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:6480464
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:6480464
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 JBrowse link 2 50,099,576 50,499,799 RGD:6480464
G Hook2 hook microtubule-tethering protein 2 JBrowse link 19 26,106,713 26,119,353 RGD:6480464
G Il1rapl1 interleukin 1 receptor accessory protein-like 1 JBrowse link X 55,439,388 57,004,865 RGD:6480464
G Kcnc2 potassium voltage-gated channel subfamily C member 2 JBrowse link 7 54,978,453 55,159,362 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 JBrowse link 3 41,019,898 41,181,070 RGD:6480464
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 JBrowse link 8 33,435,493 33,463,410 RGD:6480464
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 JBrowse link 11 35,011,007 35,262,362 RGD:6480464
G Kcnk1 potassium two pore domain channel subfamily K member 1 JBrowse link 19 58,823,836 58,862,926 RGD:6480464
G Kif1b kinesin family member 1B JBrowse link 5 165,994,803 166,133,497 RGD:6480464
G Kif2b kinesin family member 2B JBrowse link 10 79,095,588 79,097,807 RGD:6480464
G Kif5a kinesin family member 5A JBrowse link 7 70,515,832 70,552,897 RGD:6480464
G Klf6 Kruppel-like factor 6 JBrowse link 17 67,887,939 67,945,052 RGD:6480464
G Klhl24 kelch-like family member 24 JBrowse link 11 84,613,101 84,643,674 RGD:6480464
G Klk10 kallikrein related-peptidase 10 JBrowse link 1 99,718,275 99,722,743 RGD:6480464
G Large1 LARGE xylosyl- and glucuronyltransferase 1 JBrowse link 19 12,481,563 12,945,320 RGD:6480464
G Lipg lipase G, endothelial type JBrowse link 18 70,903,528 70,924,434 RGD:6480464
G Lman1 lectin, mannose-binding, 1 JBrowse link 18 61,683,377 61,707,344 RGD:6480464
G Lmo7 LIM domain 7 JBrowse link 15 86,242,911 86,458,512 RGD:6480464
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:6480464
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 4 10,995,241 12,472,423 RGD:6480464
G Map2 microtubule-associated protein 2 JBrowse link 9 73,204,753 73,462,965 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase JBrowse link 7 119,978,981 119,996,824 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpp2 membrane palmitoylated protein 2 JBrowse link 10 89,998,284 90,030,766 RGD:6480464
G Mvp major vault protein JBrowse link 1 198,420,813 198,448,612 RGD:6480464
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:6480464
G Nasp nuclear autoantigenic sperm protein JBrowse link 5 135,446,485 135,472,113 RGD:6480464
G Negr1 neuronal growth regulator 1 JBrowse link 2 262,914,240 263,650,441 RGD:6480464
G Nell2 neural EGFL like 2 JBrowse link 7 136,526,497 136,853,820 RGD:6480464
G Neurod1 neuronal differentiation 1 JBrowse link 3 66,414,314 66,417,617 RGD:6480464
G Nfix nuclear factor I X JBrowse link 19 25,818,640 25,914,777 RGD:6480464
G Nptxr neuronal pentraxin receptor JBrowse link 7 121,011,678 121,029,754 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 JBrowse link 19 34,408,275 34,761,003 RGD:6480464
G Nsun2 NOP2/Sun RNA methyltransferase 2 JBrowse link 1 36,295,650 36,319,906 RGD:6480464
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:6480464
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 139,890,537 140,262,503 RGD:6480464
G Pdap1 PDGFA associated protein 1 JBrowse link 12 11,240,775 11,251,002 RGD:6480464
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:6480464
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:6480464
G Pdia3 protein disulfide isomerase family A, member 3 JBrowse link 3 113,376,983 113,400,707 RGD:6480464
G Pdpk1 3-phosphoinositide dependent protein kinase-1 JBrowse link 10 13,446,373 13,525,248 RGD:6480464
G Pex2 peroxisomal biogenesis factor 2 JBrowse link 2 98,251,756 98,269,185 RGD:6480464
G Pgrmc1 progesterone receptor membrane component 1 JBrowse link X 123,205,869 123,213,880 RGD:6480464
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase JBrowse link 7 129,856,467 129,863,441 RGD:6480464
G Pou3f2 POU class 3 homeobox 2 JBrowse link 5 36,677,452 36,683,356 RGD:6480464
G Ppp1ca protein phosphatase 1 catalytic subunit alpha JBrowse link 1 219,439,953 219,443,570 RGD:6480464
G Ppp1r3a protein phosphatase 1, regulatory subunit 3A JBrowse link 4 41,171,486 41,212,116 RGD:6480464
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B JBrowse link 10 82,800,704 82,816,735 RGD:6480464
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha JBrowse link 14 100,311,224 100,360,879 RGD:6480464
G Prap1 proline-rich acidic protein 1 JBrowse link 1 212,558,257 212,562,053 RGD:6480464
G Prdx1 peroxiredoxin 1 JBrowse link 5 135,536,413 135,551,986 RGD:6480464
G Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 JBrowse link 5 7,622,668 7,941,715 RGD:6480464
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:6480464
G Prkg2 protein kinase cGMP-dependent 2 JBrowse link 14 12,217,121 12,313,616 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Pyy peptide YY (mapped) JBrowse link 10 90,047,989 90,049,155 RGD:6480464
G Rab14 RAB14, member RAS oncogene family JBrowse link 3 14,373,270 14,395,357 RGD:6480464
G Rab4b RAB4B, member RAS oncogene family JBrowse link 1 83,979,298 83,990,680 RGD:6480464
G Rcc1 regulator of chromosome condensation 1 JBrowse link 5 150,508,840 150,531,062 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rims1 regulating synaptic membrane exocytosis 1 JBrowse link 9 28,440,408 28,973,246 RGD:6480464
G Ring1 ring finger protein 1 JBrowse link 20 3,812,287 3,815,834 RGD:6480464
G Rph3a rabphilin 3A JBrowse link 12 41,073,296 41,149,799 RGD:6480464
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:6480464
G Serpini1 serpin family I member 1 JBrowse link 2 174,013,058 174,111,693 RGD:6480464
G Sgtb small glutamine rich tetratricopeptide repeat containing beta JBrowse link 2 34,185,938 34,222,428 RGD:6480464
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:6480464
G Sipa1l1 signal-induced proliferation-associated 1 like 1 JBrowse link 6 106,052,212 106,163,249 RGD:6480464
G Slc26a3 solute carrier family 26 member 3 JBrowse link 6 50,725,085 50,766,306 RGD:6480464
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
G Slc4a4 solute carrier family 4 member 4 JBrowse link 14 20,476,258 20,817,042 RGD:6480464
G Slc5a1 solute carrier family 5 member 1 JBrowse link 14 82,910,448 82,975,303 RGD:6480464
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:6480464
G Slc6a6 solute carrier family 6 member 6 JBrowse link 4 123,638,619 123,713,469 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6480464
G Stau2 staufen double-stranded RNA binding protein 2 JBrowse link 5 2,257,910 2,497,429 RGD:6480464
G Stk39 serine threonine kinase 39 JBrowse link 3 54,359,449 54,625,702 RGD:6480464
G Sv2b synaptic vesicle glycoprotein 2b JBrowse link 1 136,664,199 136,842,247 RGD:6480464
G Syn2 synapsin II JBrowse link 4 147,037,179 147,195,096 RGD:6480464
G Synj2 synaptojanin 2 JBrowse link 1 46,835,922 46,932,544 RGD:6480464
G Syp synaptophysin JBrowse link X 15,694,699 15,709,244 RGD:6480464
G Syt4 synaptotagmin 4 JBrowse link 18 24,172,580 24,181,989 RGD:6480464
G Tacr3 tachykinin receptor 3 JBrowse link 2 240,021,152 240,118,971 RGD:6480464
G Tcf12 transcription factor 12 JBrowse link 8 78,343,634 78,657,738 RGD:6480464
G Tcf4 transcription factor 4 JBrowse link 18 65,285,320 65,507,983 RGD:6480464
G Thbd thrombomodulin JBrowse link 3 142,748,673 142,752,325 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Trim13 tripartite motif-containing 13 JBrowse link 15 41,897,191 41,936,545 RGD:6480464
G Tshr thyroid stimulating hormone receptor JBrowse link 6 115,170,290 115,306,871 RGD:6480464
G Txn2 thioredoxin 2 JBrowse link 7 119,144,350 119,158,173 RGD:6480464
G Ube2q1 ubiquitin conjugating enzyme E2 Q1 JBrowse link 2 189,106,039 189,115,110 RGD:6480464
G Ucp3 uncoupling protein 3 JBrowse link 1 165,482,912 165,495,895 RGD:6480464
G Unc13b unc-13 homolog B JBrowse link 5 58,505,449 58,714,396 RGD:6480464
G Vamp1 vesicle-associated membrane protein 1 JBrowse link 4 157,726,941 157,733,644 RGD:6480464
G Vcpip1 valosin containing protein interacting protein 1 JBrowse link 5 9,231,180 9,257,821 RGD:6480464
G Vdac1 voltage-dependent anion channel 1 JBrowse link 10 37,724,915 37,752,827 RGD:6480464
G Vegfb vascular endothelial growth factor B JBrowse link 1 222,237,000 222,242,786 RGD:6480464
G Wdfy1 WD repeat and FYVE domain containing 1 JBrowse link 9 85,477,070 85,528,885 RGD:6480464
G Zfp24 zinc finger protein 24 JBrowse link 18 15,910,175 15,921,757 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        xenobiotic 18261
          venlafaxine 176
            venlafaxine hydrochloride 176
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                carbocyclic compound 17533
                                  benzenoid aromatic compound 17061
                                    benzenes 16782
                                      methoxybenzenes 821
                                        monomethoxybenzene 725
                                          venlafaxine 176
                                            venlafaxine hydrochloride 176
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.